STRINGSTRING
mat mat AKB34813.1 AKB34813.1 cysS cysS AKB35336.1 AKB35336.1 AKB35337.1 AKB35337.1 AKB35419.1 AKB35419.1 AKB35449.1 AKB35449.1 AKB35450.1 AKB35450.1 AKB35474.1 AKB35474.1 AKB35653.1 AKB35653.1 thiI thiI AKB36117.1 AKB36117.1 AKB36118.1 AKB36118.1 AKB36340.1 AKB36340.1 iscS iscS metXA metXA AKB36479.1 AKB36479.1 AKB36484.1 AKB36484.1 iscS-2 iscS-2 AKB36742.1 AKB36742.1 AKB36760.1 AKB36760.1 AKB36761.1 AKB36761.1 AKB36868.1 AKB36868.1 AKB37031.1 AKB37031.1 AKB37412.1 AKB37412.1 AKB37727.1 AKB37727.1 AKB38683.1 AKB38683.1 AKB38684.1 AKB38684.1 AKB38955.1 AKB38955.1 AKB38956.1 AKB38956.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
matArchaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (398 aa)
AKB34813.1Cysteine desulfurase. (393 aa)
cysSCysteinyl-tRNA synthetase. (473 aa)
AKB35336.1Hypothetical protein. (240 aa)
AKB35337.1Homocysteine desulfhydrase. (384 aa)
AKB35419.1Putative iron binding protein from the HesB_IscA_SufA family. (105 aa)
AKB35449.1Iron-sulfur cluster assembly protein SufB. (320 aa)
AKB35450.1Iron-sulfur cluster assembly ATPase protein SufC. (235 aa)
AKB35474.1Archaeal S-adenosylmethionine synthetase. (410 aa)
AKB35653.1Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (411 aa)
thiItRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (412 aa)
AKB36117.1Cysteine synthase. (316 aa)
AKB36118.1Serine acetyltransferase; PaaD-like protein (DUF59) involved in Fe-S cluster assembly. (319 aa)
AKB36340.1Scaffold protein. (119 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (396 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (536 aa)
AKB36479.1O-succinylhomoserine sulfhydrylase. (441 aa)
AKB36484.1Scaffold protein. (161 aa)
iscS-2Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (394 aa)
AKB36742.1Serine O-acetyltransferase. (143 aa)
AKB36760.1Ferredoxin. (128 aa)
AKB36761.1Inosine-5'-monophosphate dehydrogenase. (500 aa)
AKB36868.1Putative protein-S-isoprenylcysteine methyltransferase. (200 aa)
AKB37031.1Serine O-acetyltransferase. (137 aa)
AKB37412.1Methionine gamma-lyase. (394 aa)
AKB37727.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (346 aa)
AKB38683.1Iron-sulfur cluster assembly ATPase protein SufC. (247 aa)
AKB38684.1Iron-sulfur cluster assembly protein SufB. (407 aa)
AKB38955.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (347 aa)
AKB38956.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (344 aa)
Your Current Organism:
Methanosarcina siciliae
NCBI taxonomy Id: 1434118
Other names: M. siciliae C2J, Methanosarcina siciliae C2J
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