(11 nodes) Mixed, incl. Zinc-binding ribosomal protein, and Translation protein SH3-like domain superfamily network (Methanosarcina siciliae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rps9	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family. (134 aa)
	rpl44e	LSU ribosomal protein L44e; Binds to the 23S rRNA. (92 aa)
	rpl21e	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
	rpl24e	LSU ribosomal protein L24e; Binds to the 23S rRNA. (62 aa)
	rps3ae	SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (203 aa)
	rpl37e	LSU ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (56 aa)
	rpl32e	LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (152 aa)
	rpl2	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
	rpl40e	LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
	rpl10	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (347 aa)
	rpl18a	LSU ribosomal protein L18Ae. (60 aa)

Your Current Organism:

Methanosarcina siciliae

NCBI taxonomy Id: 1434118
Other names: M. siciliae C2J, Methanosarcina siciliae C2J

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpl10	rpl18a	MSSAC_3809	MSSAC_3951	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L18Ae.	0.999
rpl10	rpl2	MSSAC_3809	MSSAC_3420	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl10	rpl21e	MSSAC_3809	MSSAC_1498	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.999
rpl10	rpl24e	MSSAC_3809	MSSAC_2087	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L24e; Binds to the 23S rRNA.	0.999
rpl10	rpl32e	MSSAC_3809	MSSAC_3406	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.	0.999
rpl10	rpl37e	MSSAC_3809	MSSAC_3242	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.	0.999
rpl10	rpl40e	MSSAC_3809	MSSAC_3706	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.	0.999
rpl10	rpl44e	MSSAC_3809	MSSAC_0582	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	LSU ribosomal protein L44e; Binds to the 23S rRNA.	0.999
rpl10	rps3ae	MSSAC_3809	MSSAC_2359	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.	0.999
rpl10	rps9	MSSAC_3809	MSSAC_0527	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family.	0.999
rpl18a	rpl10	MSSAC_3951	MSSAC_3809	LSU ribosomal protein L18Ae.	LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.999
rpl18a	rpl2	MSSAC_3951	MSSAC_3420	LSU ribosomal protein L18Ae.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl18a	rpl21e	MSSAC_3951	MSSAC_1498	LSU ribosomal protein L18Ae.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.999
rpl18a	rpl24e	MSSAC_3951	MSSAC_2087	LSU ribosomal protein L18Ae.	LSU ribosomal protein L24e; Binds to the 23S rRNA.	0.999
rpl18a	rpl32e	MSSAC_3951	MSSAC_3406	LSU ribosomal protein L18Ae.	LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.	0.999
rpl18a	rpl37e	MSSAC_3951	MSSAC_3242	LSU ribosomal protein L18Ae.	LSU ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.	0.999
rpl18a	rpl40e	MSSAC_3951	MSSAC_3706	LSU ribosomal protein L18Ae.	LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.	0.999
rpl18a	rpl44e	MSSAC_3951	MSSAC_0582	LSU ribosomal protein L18Ae.	LSU ribosomal protein L44e; Binds to the 23S rRNA.	0.999
rpl18a	rps3ae	MSSAC_3951	MSSAC_2359	LSU ribosomal protein L18Ae.	SSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.	0.999
rpl18a	rps9	MSSAC_3951	MSSAC_0527	LSU ribosomal protein L18Ae.	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family.	0.999