(32 nodes) Mixed, incl. Cation efflux family, and DTXR-type HTH domain network (Methanosarcina siciliae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKB34740.1	Hypothetical protein. (90 aa)
	AKB34741.1	Hypothetical protein. (121 aa)
	AKB34742.1	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase. (650 aa)
	AKB34925.1	Hypothetical protein. (114 aa)
	AKB34926.1	Cobalt-zinc-cadmium resistance protein. (106 aa)
	AKB34927.1	Cobalt-zinc-cadmium resistance protein. (71 aa)
	AKB34928.1	Cobalt-zinc-cadmium resistance protein. (77 aa)
	AKB35068.1	Cobalt-zinc-cadmium resistance protein. (296 aa)
	AKB35070.1	Hypothetical protein. (511 aa)
	AKB35141.1	Cobalt-zinc-cadmium resistance protein. (323 aa)
	AKB35570.1	Transcriptional regulator, FUR family. (78 aa)
	AKB36576.1	Nickel responsive regulator NikR; Transcriptional regulator. (140 aa)
	AKB37173.1	Cobalt-zinc-cadmium resistance protein. (336 aa)
	AKB37641.1	Iron-dependent repressor IdeR/DtxR. (160 aa)
	AKB37646.1	Hypothetical protein. (103 aa)
	AKB37647.1	Hypothetical protein. (151 aa)
	AKB37648.1	Ferrous iron transport protein B. (665 aa)
	AKB37649.1	Ferrous iron transport protein A. (84 aa)
	AKB37650.1	Ferrous iron transport protein A. (82 aa)
	AKB37697.1	Hypothetical protein. (144 aa)
	AKB37698.1	Cobalt-zinc-cadmium resistance protein CzcD. (119 aa)
	AKB38054.1	Transcriptional regulator, FUR family. (137 aa)
	AKB38145.1	Metal-dependent hydrolase. (43 aa)
	mntP	Hypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family. (186 aa)
	AKB38574.1	Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (140 aa)
	AKB38621.1	Ferrous iron transport protein B. (659 aa)
	AKB38622.1	Iron-dependent repressor IdeR/DtxR. (224 aa)
	AKB38933.1	Putative permease. (485 aa)
	AKB38934.1	Putative zinc-dependent repressor ZntR, DtxR superfamily. (168 aa)
	AKB38935.1	Zinc ABC transporter, periplasmic-binding protein ZnuA. (327 aa)
	AKB38936.1	Zinc ABC transporter, ATP-binding protein ZnuC. (254 aa)
	AKB38937.1	Zinc ABC transporter, inner membrane permease protein ZnuB. (274 aa)

Your Current Organism:

Methanosarcina siciliae

NCBI taxonomy Id: 1434118
Other names: M. siciliae C2J, Methanosarcina siciliae C2J

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKB34740.1	AKB34741.1	MSSAC_0150	MSSAC_0151	Hypothetical protein.	Hypothetical protein.	0.773
AKB34740.1	AKB34742.1	MSSAC_0150	MSSAC_0152	Hypothetical protein.	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.	0.568
AKB34741.1	AKB34740.1	MSSAC_0151	MSSAC_0150	Hypothetical protein.	Hypothetical protein.	0.773
AKB34741.1	AKB34742.1	MSSAC_0151	MSSAC_0152	Hypothetical protein.	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.	0.568
AKB34742.1	AKB34740.1	MSSAC_0152	MSSAC_0150	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.	Hypothetical protein.	0.568
AKB34742.1	AKB34741.1	MSSAC_0152	MSSAC_0151	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.	Hypothetical protein.	0.568
AKB34742.1	AKB37698.1	MSSAC_0152	MSSAC_3108	Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.	Cobalt-zinc-cadmium resistance protein CzcD.	0.473
AKB34925.1	AKB34926.1	MSSAC_0335	MSSAC_0336	Hypothetical protein.	Cobalt-zinc-cadmium resistance protein.	0.598
AKB34925.1	AKB34927.1	MSSAC_0335	MSSAC_0337	Hypothetical protein.	Cobalt-zinc-cadmium resistance protein.	0.605
AKB34925.1	AKB34928.1	MSSAC_0335	MSSAC_0338	Hypothetical protein.	Cobalt-zinc-cadmium resistance protein.	0.592
AKB34926.1	AKB34925.1	MSSAC_0336	MSSAC_0335	Cobalt-zinc-cadmium resistance protein.	Hypothetical protein.	0.598
AKB34926.1	AKB34927.1	MSSAC_0336	MSSAC_0337	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.942
AKB34926.1	AKB34928.1	MSSAC_0336	MSSAC_0338	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.942
AKB34926.1	AKB35068.1	MSSAC_0336	MSSAC_0478	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.455
AKB34926.1	AKB35141.1	MSSAC_0336	MSSAC_0551	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.546
AKB34926.1	AKB37173.1	MSSAC_0336	MSSAC_2583	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.545
AKB34927.1	AKB34925.1	MSSAC_0337	MSSAC_0335	Cobalt-zinc-cadmium resistance protein.	Hypothetical protein.	0.605
AKB34927.1	AKB34926.1	MSSAC_0337	MSSAC_0336	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.942
AKB34927.1	AKB34928.1	MSSAC_0337	MSSAC_0338	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.942
AKB34927.1	AKB35068.1	MSSAC_0337	MSSAC_0478	Cobalt-zinc-cadmium resistance protein.	Cobalt-zinc-cadmium resistance protein.	0.471