(12 nodes) Small ribosomal subunit network (Methanosarcina siciliae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rps4	SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (218 aa)
	rps28e	SSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa)
	rps19p	SSU ribosomal protein S15e (S19p); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
	rps3	SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (308 aa)
	top6B	DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (621 aa)
	rps10	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
	rps7	SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa)
	rps12	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
	rps2	SSU ribosomal protein SAe (S2p); Belongs to the universal ribosomal protein uS2 family. (247 aa)
	rps9	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family. (134 aa)
	rps14	SSU ribosomal protein S29e (S14p); Binds 16S rRNA, required for the assembly of 30S particles. (50 aa)
	rps5	SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy. (209 aa)

Your Current Organism:

Methanosarcina siciliae

NCBI taxonomy Id: 1434118
Other names: M. siciliae C2J, Methanosarcina siciliae C2J

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rps10	rps12	MSSAC_1087	MSSAC_1083	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.999
rps10	rps14	MSSAC_1087	MSSAC_3409	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S29e (S14p); Binds 16S rRNA, required for the assembly of 30S particles.	0.999
rps10	rps19p	MSSAC_1087	MSSAC_3419	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S15e (S19p); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rps10	rps2	MSSAC_1087	MSSAC_0529	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein SAe (S2p); Belongs to the universal ribosomal protein uS2 family.	0.999
rps10	rps28e	MSSAC_1087	MSSAC_2088	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.	0.999
rps10	rps3	MSSAC_1087	MSSAC_3417	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.	0.999
rps10	rps4	MSSAC_1087	MSSAC_3104	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rps10	rps5	MSSAC_1087	MSSAC_3403	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy.	0.999
rps10	rps7	MSSAC_1087	MSSAC_1084	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.999
rps10	rps9	MSSAC_1087	MSSAC_0527	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family.	0.999
rps12	rps10	MSSAC_1083	MSSAC_1087	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S20e (S10p); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999
rps12	rps14	MSSAC_1083	MSSAC_3409	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S29e (S14p); Binds 16S rRNA, required for the assembly of 30S particles.	0.999
rps12	rps19p	MSSAC_1083	MSSAC_3419	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S15e (S19p); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rps12	rps2	MSSAC_1083	MSSAC_0529	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein SAe (S2p); Belongs to the universal ribosomal protein uS2 family.	0.999
rps12	rps28e	MSSAC_1083	MSSAC_2088	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.	0.999
rps12	rps3	MSSAC_1083	MSSAC_3417	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.	0.999
rps12	rps4	MSSAC_1083	MSSAC_3104	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S9e (S4p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rps12	rps5	MSSAC_1083	MSSAC_3403	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy.	0.999
rps12	rps7	MSSAC_1083	MSSAC_1084	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.999
rps12	rps9	MSSAC_1083	MSSAC_0527	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	SSU ribosomal protein S16e (S9p); Belongs to the universal ribosomal protein uS9 family.	0.999