STRINGSTRING
AKB38096.1 AKB38096.1 AKB38102.1 AKB38102.1 AKB38112.1 AKB38112.1 AKB38131.1 AKB38131.1 AKB38162.1 AKB38162.1 dbh-2 dbh-2 AKB38446.1 AKB38446.1 AKB38606.1 AKB38606.1 AKB38724.1 AKB38724.1 AKB38756.1 AKB38756.1 AKB38758.1 AKB38758.1 AKB38762.1 AKB38762.1 AKB38767.1 AKB38767.1 AKB38775.1 AKB38775.1 AKB38776.1 AKB38776.1 polB polB polC polC dnaG dnaG AKB34668.1 AKB34668.1 AKB34670.1 AKB34670.1 priL priL AKB34755.1 AKB34755.1 AKB35118.1 AKB35118.1 AKB35174.1 AKB35174.1 dacZ dacZ rpoL rpoL AKB35263.1 AKB35263.1 AKB35275.1 AKB35275.1 AKB35296.1 AKB35296.1 AKB35345.1 AKB35345.1 AKB35408.1 AKB35408.1 AKB35502.1 AKB35502.1 AKB35580.1 AKB35580.1 rpoH rpoH AKB35667.1 AKB35667.1 AKB35668.1 AKB35668.1 AKB35669.1 AKB35669.1 rpoA2 rpoA2 AKB35750.1 AKB35750.1 AKB35871.1 AKB35871.1 AKB35892.1 AKB35892.1 AKB35903.1 AKB35903.1 AKB36015.1 AKB36015.1 cofC cofC thiI thiI AKB36200.1 AKB36200.1 carS carS AKB36292.1 AKB36292.1 AKB36329.1 AKB36329.1 AKB36330.1 AKB36330.1 AKB36548.1 AKB36548.1 AKB36549.1 AKB36549.1 AKB36604.1 AKB36604.1 ribL ribL mobA mobA AKB36824.1 AKB36824.1 dbh dbh AKB37007.1 AKB37007.1 AKB37009.1 AKB37009.1 AKB37229.1 AKB37229.1 AKB37264.1 AKB37264.1 AKB37265.1 AKB37265.1 AKB37266.1 AKB37266.1 AKB37513.1 AKB37513.1 rpoP rpoP rpoD rpoD coaD coaD cca cca AKB37873.1 AKB37873.1 AKB37876.1 AKB37876.1 AKB37916.1 AKB37916.1 AKB37928.1 AKB37928.1 AKB38084.1 AKB38084.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB38096.1Mannose-6-phosphate isomerase, bifunctional enzyme. (446 aa)
AKB38102.1Galactose-1-phosphate uridylyltransferase. (361 aa)
AKB38112.1DNA-directed RNA polymerase subunit E'. (190 aa)
AKB38131.1Nicotinamide-nucleotide adenylyltransferase, NadM family. (173 aa)
AKB38162.1Mannose-1-phosphate guanylyltransferase (GDP); Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. (435 aa)
dbh-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (356 aa)
AKB38446.1Retron-type RNA-directed DNA polymerase. (286 aa)
AKB38606.1Nucleotidyltransferase domain protein. (82 aa)
AKB38724.1UTP--glucose-1-phosphate uridylyltransferase. (297 aa)
AKB38756.1Retron-type RNA-directed DNA polymerase. (239 aa)
AKB38758.1Retron-type RNA-directed DNA polymerase. (443 aa)
AKB38762.1Mannose-1-phosphate guanylyltransferase (GDP); Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. (455 aa)
AKB38767.1Glucose-1-phosphate cytidylyltransferase. (257 aa)
AKB38775.1Retron-type RNA-directed DNA polymerase. (457 aa)
AKB38776.1Retron-type RNA-directed DNA polymerase. (50 aa)
polBArchaeal DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (656 aa)
polCArchaeal DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1146 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (519 aa)
AKB34668.1Putative nucleotidyltransferase. (94 aa)
AKB34670.1Nucleotidyltransferase. (104 aa)
priLDNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (371 aa)
AKB34755.1Molybdenum cofactor biosynthesis protein MoaB. (179 aa)
AKB35118.1DNA-directed RNA polymerase subunit K. (37 aa)
AKB35174.1DNA primase small subunit; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (330 aa)
dacZHypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (294 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa)
AKB35263.1DNA polymerase X family. (600 aa)
AKB35275.1Hypothetical protein. (151 aa)
AKB35296.1Nucleotidyltransferase. (98 aa)
AKB35345.1tRNAHis-5'-guanylyltransferase. (188 aa)
AKB35408.1Archaeal DNA polymerase I. (935 aa)
AKB35502.1Retron-type RNA-directed DNA polymerase. (520 aa)
AKB35580.1Nucleotidyltransferase. (98 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
AKB35667.1DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family. (531 aa)
AKB35668.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa)
AKB35669.1DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (399 aa)
AKB35750.1Retron-type RNA-directed DNA polymerase. (520 aa)
AKB35871.1Retron-type RNA-directed DNA polymerase. (492 aa)
AKB35892.1Metallo-beta-lactamase family protein. (457 aa)
AKB35903.1Retron-type RNA-directed DNA polymerase. (492 aa)
AKB36015.1Nucleotidyltransferase. (116 aa)
cofC2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (208 aa)
thiItRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (412 aa)
AKB36200.1Hypothetical protein. (221 aa)
carSPhosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (175 aa)
AKB36292.1Hypothetical protein. (172 aa)
AKB36329.1Retron-type RNA-directed DNA polymerase. (191 aa)
AKB36330.1Retron-type RNA-directed DNA polymerase. (306 aa)
AKB36548.1Retron-type RNA-directed DNA polymerase. (173 aa)
AKB36549.1Retron-type RNA-directed DNA polymerase. (272 aa)
AKB36604.1Legionaminic acid cytidylyltransferase. (232 aa)
ribLFMN adenylyltransferase, type 3 archaeal; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (151 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (225 aa)
AKB36824.1Hypothetical protein. (410 aa)
dbhDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (369 aa)
AKB37007.1Mannose-6-phosphate isomerase, bifunctional enzyme. (446 aa)
AKB37009.1Nucleotidyltransferase. (76 aa)
AKB37229.1Metallo-beta-lactamase family protein. (481 aa)
AKB37264.1Retron-type RNA-directed DNA polymerase. (414 aa)
AKB37265.1Retron-type RNA-directed DNA polymerase. (50 aa)
AKB37266.1Retron-type RNA-directed DNA polymerase. (492 aa)
AKB37513.1Mannose-1-phosphate guanylyltransferase. (411 aa)
rpoPDNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (45 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa)
coaDPhosphopantetheine adenylyltransferase, type II eukaryotic; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (156 aa)
ccatRNA nucleotidyltransferase, archaeal type; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa)
AKB37873.1Glucose-1-phosphate thymidylyltransferase. (405 aa)
AKB37876.1Mannose-1-phosphate guanylyltransferase. (397 aa)
AKB37916.1Glucose-1-phosphate thymidylyltransferase. (236 aa)
AKB37928.1DNA polymerase, beta-like region. (313 aa)
AKB38084.1CRISPR-associated protein, Csh2 family. (326 aa)
Your Current Organism:
Methanosarcina siciliae
NCBI taxonomy Id: 1434118
Other names: M. siciliae C2J, Methanosarcina siciliae C2J
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