STRINGSTRING
KJD32746.1 KJD32746.1 KJD36891.1 KJD36891.1 gcvP gcvP KJD36539.1 KJD36539.1 asd asd kbl kbl KJD36633.1 KJD36633.1 KJD36830.1 KJD36830.1 KJD36177.1 KJD36177.1 thrB thrB KJD36178.1 KJD36178.1 gcvT gcvT KJD36237.1 KJD36237.1 KJD36263.1 KJD36263.1 glyA glyA gpmI gpmI KJD31915.1 KJD31915.1 KJD35905.1 KJD35905.1 KJD35414.1 KJD35414.1 ilvA ilvA gcvH gcvH KJD35282.1 KJD35282.1 KJD35283.1 KJD35283.1 KJD34219.1 KJD34219.1 trpB trpB trpA trpA serC serC KJD32762.1 KJD32762.1 KJD32738.1 KJD32738.1 KJD32743.1 KJD32743.1 KJD32755.1 KJD32755.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KJD32746.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
KJD36891.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (949 aa)
KJD36539.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (329 aa)
kbl2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)
KJD36633.1Malonic semialdehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
KJD36830.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
KJD36177.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa)
KJD36178.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (360 aa)
KJD36237.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
KJD36263.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa)
KJD31915.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (117 aa)
KJD35905.1Phosphatidylserine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (233 aa)
KJD35414.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1133 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (420 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
KJD35282.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (440 aa)
KJD35283.1X-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
KJD34219.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (473 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (254 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa)
KJD32762.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
KJD32738.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (113 aa)
KJD32743.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
KJD32755.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
Your Current Organism:
Tamlana sedimentorum
NCBI taxonomy Id: 1435349
Other names: JCM 19808, KMM 9545, NRIC 0921, T. sedimentorum, Tamlana sedimentorum Romanenko et al. 2014 emend. Hahnke et al. 2016, Tamlana sp. KMM 9545
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