28 items (Sulfolobus acidocaldarius SUSAZ) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ppcA	Phosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (511 aa)
	AHC50716.1	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
	AHC50717.1	2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
	leuD	3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (161 aa)
	leuC	3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa)
	AHC51006.1	Catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate and the decarboxylation of 3-methylmalate to 2-oxobutyrate and of D-malate to pyruvate; involved in leucine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
	AHC51121.1	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
	AHC51277.1	Trans-homoaconitate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa)
	AHC51390.1	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
	AHC51391.1	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
	AHC51392.1	(4Fe-4S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
	pckG	Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (604 aa)
	AHC51433.1	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (558 aa)
	AHC51574.1	2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
	AHC51673.1	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
	ilvC	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
	AHC51778.1	Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
	AHC51858.1	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (441 aa)
	ilvD	Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (561 aa)
	AHC51936.1	Benzoylformate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (483 aa)
	AHC52275.1	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
	AHC52276.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
	AHC52277.1	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	AHC52278.1	2-ketoisovalerate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
	AHC52304.1	Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
	AHC52328.1	2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
	AHC52329.1	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
	AHC52343.1	Alpha-isopropylmalate/homocitrate synthase family transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (523 aa)

Your Current Organism:

Sulfolobus acidocaldarius SUSAZ

NCBI taxonomy Id: 1435377
Other names: S. acidocaldarius SUSAZ

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHC50716.1	AHC50717.1	SUSAZ_01050	SUSAZ_01055	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AHC50716.1	AHC51277.1	SUSAZ_01050	SUSAZ_04310	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trans-homoaconitate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.914
AHC50716.1	AHC51390.1	SUSAZ_01050	SUSAZ_05070	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.605
AHC50716.1	AHC51391.1	SUSAZ_01050	SUSAZ_05075	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944
AHC50716.1	AHC51392.1	SUSAZ_01050	SUSAZ_05080	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	(4Fe-4S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.886
AHC50716.1	AHC51433.1	SUSAZ_01050	SUSAZ_05320	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.	0.914
AHC50716.1	AHC51574.1	SUSAZ_01050	SUSAZ_06230	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AHC50716.1	AHC51673.1	SUSAZ_01050	SUSAZ_06780	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.	0.916
AHC50716.1	AHC51778.1	SUSAZ_01050	SUSAZ_07375	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AHC50716.1	AHC51858.1	SUSAZ_01050	SUSAZ_07800	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.	0.928
AHC50716.1	AHC52275.1	SUSAZ_01050	SUSAZ_10555	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.964
AHC50716.1	AHC52276.1	SUSAZ_01050	SUSAZ_10560	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.886
AHC50716.1	AHC52277.1	SUSAZ_01050	SUSAZ_10565	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.954
AHC50716.1	AHC52278.1	SUSAZ_01050	SUSAZ_10570	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-ketoisovalerate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.629
AHC50716.1	AHC52304.1	SUSAZ_01050	SUSAZ_10715	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AHC50716.1	AHC52328.1	SUSAZ_01050	SUSAZ_10840	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AHC50716.1	AHC52329.1	SUSAZ_01050	SUSAZ_10845	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
AHC50716.1	AHC52343.1	SUSAZ_01050	SUSAZ_10950	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-isopropylmalate/homocitrate synthase family transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.914
AHC50716.1	leuC	SUSAZ_01050	SUSAZ_01285	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.820
AHC50716.1	leuD	SUSAZ_01050	SUSAZ_01280	2-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.	0.813