STRINGSTRING
AHC50534.1 AHC50534.1 AHC50547.1 AHC50547.1 nep1 nep1 AHC50600.1 AHC50600.1 AHC50702.1 AHC50702.1 AHC50721.1 AHC50721.1 AHC50783.1 AHC50783.1 AHC50930.1 AHC50930.1 tfe tfe AHC51053.1 AHC51053.1 radA radA AHC51094.1 AHC51094.1 AHC51098.1 AHC51098.1 AHC51100.1 AHC51100.1 rps8e rps8e AHC51123.1 AHC51123.1 fen fen AHC51139.1 AHC51139.1 lig lig AHC51161.1 AHC51161.1 AHC51162.1 AHC51162.1 endA endA AHC51235.1 AHC51235.1 AHC51237.1 AHC51237.1 AHC51244.1 AHC51244.1 AHC51261.1 AHC51261.1 AHC51295.1 AHC51295.1 AHC51311.1 AHC51311.1 AHC51341.1 AHC51341.1 AHC51369.1 AHC51369.1 AHC51385.1 AHC51385.1 AHC51412.1 AHC51412.1 AHC51423.1 AHC51423.1 AHC51426.1 AHC51426.1 AHC52494.1 AHC52494.1 AHC51439.1 AHC51439.1 AHC51552.1 AHC51552.1 top6A top6A AHC51594.1 AHC51594.1 tbp tbp AHC51607.1 AHC51607.1 flpA flpA AHC51614.1 AHC51614.1 pdxS pdxS AHC51820.1 AHC51820.1 AHC51866.1 AHC51866.1 AHC51965.1 AHC51965.1 AHC52055.1 AHC52055.1 AHC52165.1 AHC52165.1 AHC52217.1 AHC52217.1 AHC52221.1 AHC52221.1 AHC52252.1 AHC52252.1 AHC52319.1 AHC52319.1 AHC52369.1 AHC52369.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHC50534.1Cell division control protein Cdc6; Involved in regulation of DNA replication. (386 aa)
AHC50547.1Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
nep116S rRNA methyltransferase; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (219 aa)
AHC50600.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AHC50702.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
AHC50721.1Acetylpolyamine aminohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AHC50783.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (746 aa)
AHC50930.1Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (189 aa)
tfeTranscription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (179 aa)
AHC51053.1tRNA-splicing endonuclease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (321 aa)
AHC51094.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AHC51098.1Cell division control protein Cdc6; Involved in regulation of DNA replication. (397 aa)
AHC51100.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
rps8e30S ribosomal protein S8; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AHC51123.150S ribosomal protein L40; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (56 aa)
fenEndonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] (302 aa)
AHC51139.1RNA procession exonuclease-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (598 aa)
AHC51161.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AHC51162.1tRNA pseudouridine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
endAtRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (181 aa)
AHC51235.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
AHC51237.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
AHC51244.1Cell division control protein Cdc6; Involved in regulation of DNA replication. (418 aa)
AHC51261.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AHC51295.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AHC51311.1Single-stranded DNA-binding protein; In Sulfolobus solfataricus this protein plays a role in promoter opening and RNA polymerase recruitment under specific conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
AHC51341.1Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AHC51369.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
AHC51385.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
AHC51412.1fatty-acid-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
AHC51423.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
AHC51426.1fatty-acid-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
AHC52494.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (589 aa)
AHC51439.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
AHC51552.1Ribosome biogenesis protein Nop10; Derived by automated computational analysis using gene prediction method: Protein Homology. (56 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (386 aa)
AHC51594.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
tbpTATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (166 aa)
AHC51607.1H/ACA RNA-protein complex protein Gar1; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
flpASAM-dependent methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (231 aa)
AHC51614.1C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; Functions along with aFIB and aL7a; guides 2'-O-methylation of ribose to specific sites in RNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
pdxSPyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (336 aa)
AHC51820.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AHC51866.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AHC51965.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
AHC52055.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
AHC52165.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
AHC52217.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
AHC52221.1fatty-acid-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
AHC52252.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
AHC52319.1Pirin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pirin family. (293 aa)
AHC52369.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
Your Current Organism:
Sulfolobus acidocaldarius SUSAZ
NCBI taxonomy Id: 1435377
Other names: S. acidocaldarius SUSAZ
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