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AHC50692.1 AHC50692.1 AHC50693.1 AHC50693.1 aroB aroB aroE aroE aroC aroC aroK aroK AHC50698.1 AHC50698.1 aroD aroD AHC50941.1 AHC50941.1 AHC51088.1 AHC51088.1 trpB trpB trpA trpA trpD trpD trpF trpF trpE trpE AHC51682.1 AHC51682.1 trpC trpC AHC51684.1 AHC51684.1 AHC51790.1 AHC51790.1 aroE-2 aroE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHC50692.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AHC50693.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (353 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (263 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (391 aa)
aroKShikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AHC50698.13-phosphoshikimate 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (216 aa)
AHC50941.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AHC51088.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (424 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (241 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (199 aa)
trpEAnthranilate synthase subunit I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrat [...] (432 aa)
AHC51682.1Anthranilate synthase subunit II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
trpCIndole-3-glycerol-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (248 aa)
AHC51684.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AHC51790.1Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
aroE-2AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
Your Current Organism:
Sulfolobus acidocaldarius SUSAZ
NCBI taxonomy Id: 1435377
Other names: S. acidocaldarius SUSAZ
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