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AHC50556.1 AHC50556.1 AHC50570.1 AHC50570.1 ppcA ppcA AHC50587.1 AHC50587.1 AHC50633.1 AHC50633.1 tpiA tpiA AHC50643.1 AHC50643.1 AHC50654.1 AHC50654.1 AHC50667.1 AHC50667.1 AHC50690.1 AHC50690.1 AHC50691.1 AHC50691.1 AHC50716.1 AHC50716.1 AHC50717.1 AHC50717.1 AHC50732.1 AHC50732.1 AHC50733.1 AHC50733.1 AHC50734.1 AHC50734.1 AHC50747.1 AHC50747.1 AHC50750.1 AHC50750.1 AHC50762.1 AHC50762.1 AHC50763.1 AHC50763.1 AHC50764.1 AHC50764.1 AHC50804.1 AHC50804.1 AHC50818.1 AHC50818.1 AHC50823.1 AHC50823.1 AHC50824.1 AHC50824.1 AHC50826.1 AHC50826.1 AHC50827.1 AHC50827.1 AHC50832.1 AHC50832.1 AHC50836.1 AHC50836.1 gcvH gcvH gcvH-2 gcvH-2 AHC50904.1 AHC50904.1 fbp fbp AHC51089.1 AHC51089.1 AHC51107.1 AHC51107.1 AHC51154.1 AHC51154.1 apgM apgM AHC51228.1 AHC51228.1 AHC51252.1 AHC51252.1 AHC51263.1 AHC51263.1 AHC51264.1 AHC51264.1 AHC51299.1 AHC51299.1 AHC51314.1 AHC51314.1 sdhC sdhC AHC51316.1 AHC51316.1 sdhA sdhA AHC51375.1 AHC51375.1 AHC51382.1 AHC51382.1 gdh gdh AHC51390.1 AHC51390.1 AHC51391.1 AHC51391.1 AHC51392.1 AHC51392.1 AHC51410.1 AHC51410.1 AHC51416.1 AHC51416.1 AHC51422.1 AHC51422.1 AHC51430.1 AHC51430.1 AHC51431.1 AHC51431.1 AHC51448.1 AHC51448.1 AHC51454.1 AHC51454.1 AHC51475.1 AHC51475.1 AHC51503.1 AHC51503.1 AHC51547.1 AHC51547.1 AHC51548.1 AHC51548.1 prs prs AHC51573.1 AHC51573.1 pgk pgk gap gap glyA glyA AHC51626.1 AHC51626.1 AHC51630.1 AHC51630.1 eno eno AHC51642.1 AHC51642.1 gcvPA gcvPA AHC51644.1 AHC51644.1 gcvH-3 gcvH-3 AHC51673.1 AHC51673.1 AHC51838.1 AHC51838.1 AHC51845.1 AHC51845.1 AHC51858.1 AHC51858.1 AHC51931.1 AHC51931.1 AHC51958.1 AHC51958.1 AHC52089.1 AHC52089.1 AHC52160.1 AHC52160.1 AHC52162.1 AHC52162.1 AHC52163.1 AHC52163.1 AHC52164.1 AHC52164.1 AHC52172.1 AHC52172.1 AHC52200.1 AHC52200.1 AHC52201.1 AHC52201.1 AHC52219.1 AHC52219.1 AHC52249.1 AHC52249.1 AHC52258.1 AHC52258.1 AHC52259.1 AHC52259.1 AHC52261.1 AHC52261.1 AHC52275.1 AHC52275.1 AHC52276.1 AHC52276.1 AHC52277.1 AHC52277.1 AHC52278.1 AHC52278.1 AHC52293.1 AHC52293.1 AHC52294.1 AHC52294.1 AHC52295.1 AHC52295.1 AHC52310.1 AHC52310.1 AHC52320.1 AHC52320.1 AHC52328.1 AHC52328.1 AHC52329.1 AHC52329.1 AHC52375.1 AHC52375.1 AHC52380.1 AHC52380.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHC50556.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
AHC50570.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (511 aa)
AHC50587.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AHC50633.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa)
AHC50643.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
AHC50654.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (414 aa)
AHC50667.1Phosphomannose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AHC50690.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AHC50691.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AHC50716.12-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AHC50717.12-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
AHC50732.12-keto-3-deoxy gluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AHC50733.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AHC50734.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
AHC50747.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
AHC50750.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (306 aa)
AHC50762.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
AHC50763.1Biotin carboxyl carrier protein of propionyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
AHC50764.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
AHC50804.13-hydroxypropionyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)
AHC50818.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (976 aa)
AHC50823.1Disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AHC50824.1Heterodisulfide reductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AHC50826.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
AHC50827.1Heterodisulfide reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
AHC50832.1Heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AHC50836.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (444 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (146 aa)
gcvH-2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (149 aa)
AHC50904.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
fbpFructose-1 6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (385 aa)
AHC51089.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AHC51107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AHC51154.1D-arabino 3-hexulose 6-phosphate aldehyde lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (413 aa)
AHC51228.1Mandelate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AHC51252.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AHC51263.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AHC51264.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AHC51299.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AHC51314.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
sdhCDisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AHC51316.1Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
AHC51375.1MaoC family dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
AHC51382.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
gdhAlcohol dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. (364 aa)
AHC51390.1Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AHC51391.1Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AHC51392.1(4Fe-4S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
AHC51410.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (663 aa)
AHC51416.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AHC51422.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A; it can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AHC51430.1Crotonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AHC51431.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (662 aa)
AHC51448.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AHC51454.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AHC51475.13-hydroxypropionyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
AHC51503.1Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)
AHC51547.1succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AHC51548.1succinyl-CoA synthetase subunit alpha; Catalyzes the only substrate-level phosphorylation in the TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (291 aa)
AHC51573.1Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (415 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (433 aa)
AHC51626.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AHC51630.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (416 aa)
AHC51642.1Glycine dehydrogenase subunit 2; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
gcvPAGlycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (447 aa)
AHC51644.1Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
gcvH-3Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (138 aa)
AHC51673.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
AHC51838.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AHC51845.1Crotonase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
AHC51858.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (441 aa)
AHC51931.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
AHC51958.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
AHC52089.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
AHC52160.14-hydroxybutyryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
AHC52162.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
AHC52163.1fatty-acid-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
AHC52164.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
AHC52172.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
AHC52200.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (824 aa)
AHC52201.1Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AHC52219.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A; it can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AHC52249.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
AHC52258.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AHC52259.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
AHC52261.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
AHC52275.1Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
AHC52276.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AHC52277.1Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AHC52278.12-ketoisovalerate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AHC52293.1Carbon monoxide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AHC52294.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
AHC52295.1Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (748 aa)
AHC52310.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A; it can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
AHC52320.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)
AHC52328.12-oxoacid:ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
AHC52329.12-oxoacid ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AHC52375.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AHC52380.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
Your Current Organism:
Sulfolobus acidocaldarius SUSAZ
NCBI taxonomy Id: 1435377
Other names: S. acidocaldarius SUSAZ
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