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AHC50747.1 AHC50747.1 leuD leuD leuC leuC AHC51006.1 AHC51006.1 lysY lysY lysZ lysZ AHC51114.1 AHC51114.1 lysJ lysJ lysK lysK AHC51277.1 AHC51277.1 AHC51433.1 AHC51433.1 AHC51503.1 AHC51503.1 AHC51574.1 AHC51574.1 AHC51668.1 AHC51668.1 AHC51669.1 AHC51669.1 AHC51684.1 AHC51684.1 AHC51741.1 AHC51741.1 ilvC ilvC AHC51778.1 AHC51778.1 AHC51836.1 AHC51836.1 ilvD ilvD AHC52304.1 AHC52304.1 AHC52343.1 AHC52343.1 AHC52380.1 AHC52380.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHC50747.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (161 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa)
AHC51006.1Catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate and the decarboxylation of 3-methylmalate to 2-oxobutyrate and of D-malate to pyruvate; involved in leucine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
lysYN-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (350 aa)
lysZAcetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (261 aa)
AHC51114.1alpha-aminoadipate--lysW ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
lysJAcetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (387 aa)
lysKAcetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (346 aa)
AHC51277.1Trans-homoaconitate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (386 aa)
AHC51433.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (558 aa)
AHC51503.1Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)
AHC51574.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
AHC51668.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AHC51669.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (446 aa)
AHC51684.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
AHC51741.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
AHC51778.1Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
AHC51836.130S ribosomal protein S6 modification protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (561 aa)
AHC52304.1Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
AHC52343.1Alpha-isopropylmalate/homocitrate synthase family transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (523 aa)
AHC52380.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
Your Current Organism:
Sulfolobus acidocaldarius SUSAZ
NCBI taxonomy Id: 1435377
Other names: S. acidocaldarius SUSAZ
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