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| | BISA_2298 | IstB-like ATP-binding protein. (57 aa) |
| | BISA_0052 | ATP-dependent DNA helicase RecQ. (644 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (696 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa) |
| | BISA_0102 | Putative virion core protein (lumpy skin disease virus). (408 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | BISA_0178 | Exopolyphosphatase. (405 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (239 aa) |
| | rplQ | 50S ribosomal protein L17. (165 aa) |
| | rpsK | 30S ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa) |
| | rpmJ | 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (150 aa) |
| | rpmD | Rpmd. (61 aa) |
| | rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (242 aa) |
| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (123 aa) |
| | BISA_0295 | Ribosomal protein S8. (43 aa) |
| | rpsZ | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (190 aa) |
| | rplX | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (111 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa) |
| | rpmC | 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (83 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (266 aa) |
| | rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (213 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | rpsI | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (163 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (149 aa) |
| | rpmG | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | BISA_0349 | Forkhead-associated protein. (486 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (127 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (173 aa) |
| | rpmB | 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (64 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (223 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (82 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa) |
| | BISA_0465 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (481 aa) |
| | BISA_0474 | Dipeptidase. (562 aa) |
| | BISA_0491 | FMN-binding domain-containing protein. (180 aa) |
| | BISA_0528 | Dipeptidase. (533 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (996 aa) |
| | BISA_0551 | Hypothetical protein. (142 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa) |
| | BISA_0560 | Tadc. (216 aa) |
| | BISA_0561 | Flp pilus assembly protein. (211 aa) |
| | BISA_0562 | Type II/IV secretion system protein. (332 aa) |
| | BISA_0611 | ADP-ribosylglycohydrolase. (354 aa) |
| | BISA_0625 | Hypothetical protein; Belongs to the SOS response-associated peptidase family. (231 aa) |
| | BISA_0633 | Hypothetical protein. (1174 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa) |
| | rplY | Ribosomal 5S rRNA E-loop-binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (207 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (196 aa) |
| | BISA_0862 | Hypothetical protein. (359 aa) |
| | BISA_0887 | Superfamily ii RNA helicase. (858 aa) |
| | rpsB | SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (276 aa) |
| | BISA_0977 | Protein kinase. (674 aa) |
| | gyrB | DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (722 aa) |
| | recF | Recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (398 aa) |
| | rpmH | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
| | BISA_1030 | ATPase for chromosome partitioning. (322 aa) |
| | BISA_1031 | Chromosome partitioning protein ParB; Belongs to the ParB family. (436 aa) |
| | BISA_1060 | L-ribulose-5-phosphate 4-epimerase. (230 aa) |
| | rpmF | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (64 aa) |
| | rpsP | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (154 aa) |
| | BISA_1108 | ABC transporter, substrate-binding protein. (422 aa) |
| | rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | BISA_1158 | Primosome assembly protein PriA. (760 aa) |
| | BISA_2299 | IstB-like ATP-binding protein. (163 aa) |
| | BISA_1166 | DNA-binding protein HB1; Belongs to the bacterial histone-like protein family. (93 aa) |
| | BISA_1191 | Hypothetical protein. (480 aa) |
| | BISA_1202 | Superfamily ii helicase. (857 aa) |
| | BISA_1203 | AAA ATPase. (309 aa) |
| | BISA_1204 | ATPase related to the helicase subunit of the Holliday junction resolvase. (150 aa) |
| | BISA_1234 | Putative tetratricopeptide repeat-containing domain protein. (1141 aa) |
| | BISA_1278 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (578 aa) |
| | BISA_1324 | 30S ribosomal protein S1. (491 aa) |
| | BISA_1357 | Hypothetical protein. (469 aa) |
| | BISA_1392 | ATP-dependent DNA helicase RecQ. (574 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1216 aa) |
| | rpmI | 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa) |
| | BISA_1491 | Sporulation initiation inhibitor protein Soj. (299 aa) |
| | hpf | Ribosome-associated factor Y; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (220 aa) |
| | BISA_1549 | Serine-threonine protein kinase. (761 aa) |
| | BISA_1603 | Zinc finger protein. (265 aa) |
| | BISA_1604 | Chromosome partitioning protein parB; Belongs to the ParB family. (515 aa) |
| | BISA_1655 | Putative tetratricopeptide repeat-containing domain protein. (712 aa) |
| | BISA_1715 | Sugar ABC transporter substrate-binding protein. (453 aa) |
| | BISA_1769 | Hypothetical protein; Belongs to the ParB family. (483 aa) |
| | BISA_1862 | DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (362 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (70 aa) |
| | BISA_1963 | Family 1 extracellular solute-binding protein. (424 aa) |
| | BISA_1993 | Rep replicase. (403 aa) |
| | BISA_2102 | Tetratricopeptide TPR_2 repeat protein. (1114 aa) |
| | BISA_2105 | Putative periplasmic binding (signal peptide) ABC transporter protein. (417 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa) |
| | obg | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (560 aa) |
| | BISA_2148 | ABC transporter ATP-binding protein. (438 aa) |
| | BISA_2182 | MalE-type ABC sugar transport system periplasmic component. (429 aa) |
| | BISA_2187 | Silent information regulator protein Sir2. (251 aa) |
| | BISA_2201 | Lipopolysaccharide kinase (Kdo/WaaP) family protein. (469 aa) |
| | BISA_2222 | Topoisomerase III. (716 aa) |
| | BISA_2293 | IstB-like ATP-binding protein. (261 aa) |
