STRINGSTRING
APT87975.1 APT87975.1 gabD2 gabD2 APT87990.1 APT87990.1 amn amn APT88004.1 APT88004.1 APT88025.1 APT88025.1 APT88027.1 APT88027.1 APT88062.1 APT88062.1 APT88064.1 APT88064.1 fabG fabG APT88066.1 APT88066.1 APT88067.1 APT88067.1 APT88068.1 APT88068.1 APT88083.1 APT88083.1 APT88099.1 APT88099.1 APT88110.1 APT88110.1 pxpA pxpA leuA leuA APT88156.1 APT88156.1 APT88159.1 APT88159.1 sdhA sdhA APT88161.1 APT88161.1 APT88168.1 APT88168.1 APT88170.1 APT88170.1 APT88218.1 APT88218.1 guaB guaB APT88322.1 APT88322.1 guaA guaA APT88347.1 APT88347.1 APT88348.1 APT88348.1 folD folD APT88356.1 APT88356.1 APT88366.1 APT88366.1 upp upp APT88373.1 APT88373.1 APT88374.1 APT88374.1 APT88375.1 APT88375.1 APT88376.1 APT88376.1 APT88377.1 APT88377.1 APT88379.1 APT88379.1 APT88384.1 APT88384.1 APT88386.1 APT88386.1 purK purK purE purE fabG-2 fabG-2 APT88471.1 APT88471.1 APT88479.1 APT88479.1 APT88484.1 APT88484.1 thyA thyA APT88492.1 APT88492.1 purN purN purH purH APT88544.1 APT88544.1 APT88551.1 APT88551.1 purU purU prs prs glyA glyA aspA aspA APT88592.1 APT88592.1 APT88593.1 APT88593.1 APT88597.1 APT88597.1 APT88604.1 APT88604.1 APT88605.1 APT88605.1 APT88606.1 APT88606.1 APT88607.1 APT88607.1 selD selD APT88611.1 APT88611.1 glcB glcB APT88619.1 APT88619.1 kgd kgd APT88652.1 APT88652.1 APT88670.1 APT88670.1 APT88671.1 APT88671.1 APT88672.1 APT88672.1 APT88686.1 APT88686.1 APT88726.1 APT88726.1 apt apt APT88742.1 APT88742.1 APT88743.1 APT88743.1 pyrR pyrR pyrC pyrC carA carA carB carB APT88762.1 APT88762.1 gmk gmk ppc ppc APT88808.1 APT88808.1 acnA acnA pyrD pyrD fhs fhs APT88867.1 APT88867.1 APT88868.1 APT88868.1 APT88869.1 APT88869.1 APT88933.1 APT88933.1 APT88934.1 APT88934.1 APT88935.1 APT88935.1 leuD leuD leuC leuC APT88962.1 APT88962.1 leuB leuB ilvC ilvC APT88979.1 APT88979.1 ilvD ilvD APT89009.1 APT89009.1 APT89010.1 APT89010.1 thyX thyX APT89085.1 APT89085.1 mqo mqo APT89101.1 APT89101.1 APT89144.1 APT89144.1 APT89145.1 APT89145.1 APT89149.1 APT89149.1 APT89155.1 APT89155.1 APT89250.1 APT89250.1 pepA pepA APT89253.1 APT89253.1 APT89254.1 APT89254.1 gcvT gcvT gcvH gcvH lipB lipB lipA lipA APT89261.1 APT89261.1 APT89265.1 APT89265.1 APT89273.1 APT89273.1 glnE glnE APT89275.1 APT89275.1 APT89284.1 APT89284.1 APT89287.1 APT89287.1 APT89319.1 APT89319.1 APT89336.1 APT89336.1 mdh mdh APT89389.1 APT89389.1 APT89390.1 APT89390.1 APT89396.1 APT89396.1 APT89407.1 APT89407.1 APT89421.1 APT89421.1 APT89429.1 APT89429.1 acpS acpS APT89493.1 APT89493.1 purM purM purQ purQ APT89515.1 APT89515.1 APT89520.1 APT89520.1 purC purC APT89522.1 APT89522.1 purD purD APT89528.1 APT89528.1 APT89560.1 APT89560.1 tilS tilS APT89562.1 APT89562.1 APT89564.1 APT89564.1 APT89569.1 APT89569.1 APT89570.1 APT89570.1 APT89575.1 APT89575.1 ackA ackA APT89588.1 APT89588.1 APT89592.1 APT89592.1 purA purA pyrE pyrE APT89636.1 APT89636.1 pckG pckG APT89657.1 APT89657.1 APT89686.1 APT89686.1 ldh ldh APT89730.1 APT89730.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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APT87975.13-hydroxy-2-methylbutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (257 aa)
gabD2NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
APT87990.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (468 aa)
APT88004.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
APT88025.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
APT88027.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
APT88062.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
APT88064.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
fabG3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
APT88066.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
APT88067.1Peptidase M13; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
APT88068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
APT88083.1NADPH:quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
APT88099.1Formamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
APT88110.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
pxpAHypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (251 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (606 aa)
APT88156.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
APT88159.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
APT88161.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
APT88168.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3139 aa)
APT88170.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
APT88218.1Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (506 aa)
APT88322.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa)
APT88347.1Fumarate hydrolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
APT88348.1Involved in the tartrate degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
APT88356.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
APT88366.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (214 aa)
APT88373.1Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
APT88374.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
APT88375.1Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (308 aa)
APT88376.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
APT88377.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1137 aa)
APT88379.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
APT88384.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
APT88386.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (406 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa)
fabG-23-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
APT88471.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
APT88479.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (430 aa)
APT88484.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dihydrofolate reductase family. (196 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (269 aa)
APT88492.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (486 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
APT88544.13-hydroxyisobutyryl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
APT88551.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
APT88592.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
APT88593.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
APT88597.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (287 aa)
APT88604.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
APT88605.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (903 aa)
APT88606.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
APT88607.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
selDSegregation protein B; Synthesizes selenophosphate from selenide and ATP. (334 aa)
APT88611.1Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (736 aa)
APT88619.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1262 aa)
APT88652.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
APT88670.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APT88671.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
APT88672.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
APT88686.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
APT88726.1acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (188 aa)
APT88742.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (506 aa)
APT88743.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
pyrRUracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (194 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (381 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1123 aa)
APT88762.1Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (265 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (195 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (922 aa)
APT88808.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
acnAAconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (938 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (552 aa)
APT88867.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
APT88868.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
APT88869.1Pyruvate formate lyase-activating protein; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (291 aa)
APT88933.1Pyrimidine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
APT88934.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (130 aa)
APT88935.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
APT88962.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (340 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
APT88979.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (616 aa)
APT89009.1Electron transfer flavoprotein subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
APT89010.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
thyXThymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (252 aa)
APT89085.1Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
APT89101.1Catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
APT89144.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (687 aa)
APT89145.1Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
APT89149.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
APT89155.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
APT89250.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
pepAAminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (533 aa)
APT89253.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
APT89254.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. (971 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (369 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
lipBLipoate--protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (314 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (366 aa)
APT89261.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
APT89265.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (478 aa)
APT89273.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
glnEGlutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] (1045 aa)
APT89275.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
APT89284.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (918 aa)
APT89287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
APT89319.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
APT89336.1Uracil-xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (324 aa)
APT89389.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
APT89390.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
APT89396.13-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
APT89407.1Derived by automated computational analysis using gene prediction method: Protein Homology. (876 aa)
APT89421.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
APT89429.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (132 aa)
APT89493.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
purMPhosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (235 aa)
APT89515.1Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
APT89520.13-carboxy-cis,cis-muconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (298 aa)
APT89522.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (447 aa)
APT89528.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (582 aa)
APT89560.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (194 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (338 aa)
APT89562.1D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
APT89564.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
APT89569.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
APT89570.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
APT89575.1Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (377 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
APT89588.1Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
APT89592.1Hypothetical protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (407 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa)
APT89636.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (606 aa)
APT89657.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
APT89686.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)
APT89730.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
Your Current Organism:
Corynebacterium frankenforstense
NCBI taxonomy Id: 1437875
Other names: C. frankenforstense DSM 45800, Corynebacterium frankenforstense DSM 45800, Corynebacterium sp. ST18
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