(56 nodes) Mixed, incl. ERAD pathway, and Domain present in ubiquitin-regulatory proteins network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pex6	Peroxisomal biogenesis factor 6. (1038 aa)
	yod1	YOD1 deubiquitinase. (324 aa)
	ENSSPAP00000000794	Ubiquitin-like domain-containing protein. (77 aa)
	fignl1	Fidgetin-like 1; Belongs to the AAA ATPase family. (647 aa)
	amfr	Autocrine motility factor receptor b. (622 aa)
	ubl7	Ubiquitin-like 7b (bone marrow stromal cell-derived). (379 aa)
	ENSSPAP00000002357	Si:dkey-195m11.8. (193 aa)
	UBB	Ubiquitin B. (258 aa)
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	LOC103361054	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (246 aa)
	LOC103361078	Uncharacterized protein. (172 aa)
	ube4a	Ubiquitination factor E4A (UFD2 homolog, yeast). (1077 aa)
	rnf145	Ring finger protein 145b. (770 aa)
	ENSSPAP00000007940	UBX domain-containing protein. (138 aa)
	ENSSPAP00000007955	Uncharacterized protein. (77 aa)
	erlin1	ER lipid raft associated 1. (338 aa)
	aspscr1	ASPSCR1 tether for SLC2A4, UBX domain containing. (613 aa)
	LOC103369541	Zmp:0000000662. (814 aa)
	FIGNL2	Fidgetin like 2. (684 aa)
	LOC103356237	UBA domain-containing protein. (102 aa)
	ube2g2	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (217 aa)
	ubxn7	UBX domain protein 7. (539 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (748 aa)
	chfr	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (642 aa)
	ubxn2a	UBX domain protein 2A. (250 aa)
	nsfl1c	NSFL1 (p97) cofactor (p47). (373 aa)
	LOC103354599	AAA domain-containing protein. (755 aa)
	ube4b	Ubiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1380 aa)
	syvn1	Synovial apoptosis inhibitor 1, synoviolin. (643 aa)
	LOC103374193	UBX domain protein 1. (305 aa)
	SPATA5	Spermatogenesis associated 5. (707 aa)
	rnf185	Ring finger protein 185. (193 aa)
	os9	OS9 endoplasmic reticulum lectin. (676 aa)
	RNF5	Ring finger protein 5. (213 aa)
	ENSSPAP00000017495	SEP domain-containing protein. (243 aa)
	ENSSPAP00000018269	Uncharacterized protein. (777 aa)
	zfand4	Zinc finger, AN1-type domain 4. (733 aa)
	LOC103353588	Si:dkey-24p1.6. (1022 aa)
	ubxn6	UBX domain protein 6. (439 aa)
	LOC103354173	Cytochrome c oxidase assembly factor 7. (230 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (310 aa)
	nploc4	NPL4 homolog, ubiquitin recognition factor. (614 aa)
	ubqln4	Ubiquilin 4. (599 aa)
	pex1	Peroxisomal biogenesis factor 1. (1239 aa)
	dele1	Uncharacterized protein. (529 aa)
	LOC103357444	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ENSSPAP00000023324	Uncharacterized protein. (64 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (258 aa)
	faf2	Fas associated factor family member 2. (445 aa)
	plaa	Phospholipase A2-activating protein. (798 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (674 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (748 aa)
	LOC103374416	Zgc:136908; Belongs to the AAA ATPase family. (807 aa)
	erlec1	Endoplasmic reticulum lectin 1. (484 aa)
	svip	Si:ch73-147o17.1. (89 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000000794	ENSSPAP00000002357	ENSSPAP00000000794	ENSSPAP00000002357	Ubiquitin-like domain-containing protein.	Si:dkey-195m11.8.	0.578
ENSSPAP00000000794	ENSSPAP00000023324	ENSSPAP00000000794	ENSSPAP00000023324	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.608
ENSSPAP00000000794	FIGNL2	ENSSPAP00000000794	ENSSPAP00000010429	Ubiquitin-like domain-containing protein.	Fidgetin like 2.	0.578
ENSSPAP00000000794	LOC103354599	ENSSPAP00000000794	ENSSPAP00000013260	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.578
ENSSPAP00000000794	LOC103356237	ENSSPAP00000000794	ENSSPAP00000011403	Ubiquitin-like domain-containing protein.	UBA domain-containing protein.	0.637
ENSSPAP00000000794	LOC103357444	ENSSPAP00000000794	ENSSPAP00000022672	Ubiquitin-like domain-containing protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.829
ENSSPAP00000000794	LOC103369541	ENSSPAP00000000794	ENSSPAP00000010354	Ubiquitin-like domain-containing protein.	Zmp:0000000662.	0.608
ENSSPAP00000000794	LOC103374193	ENSSPAP00000000794	ENSSPAP00000014110	Ubiquitin-like domain-containing protein.	UBX domain protein 1.	0.637
ENSSPAP00000000794	LOC103374416	ENSSPAP00000000794	ENSSPAP00000027948	Ubiquitin-like domain-containing protein.	Zgc:136908; Belongs to the AAA ATPase family.	0.829
ENSSPAP00000000794	RNF5	ENSSPAP00000000794	ENSSPAP00000017281	Ubiquitin-like domain-containing protein.	Ring finger protein 5.	0.712
ENSSPAP00000000794	SPATA5	ENSSPAP00000000794	ENSSPAP00000015129	Ubiquitin-like domain-containing protein.	Spermatogenesis associated 5.	0.829
ENSSPAP00000000794	UBB	ENSSPAP00000000794	ENSSPAP00000003565	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.992
ENSSPAP00000000794	amfr	ENSSPAP00000000794	ENSSPAP00000001584	Ubiquitin-like domain-containing protein.	Autocrine motility factor receptor b.	0.842
ENSSPAP00000000794	chfr	ENSSPAP00000000794	ENSSPAP00000012435	Ubiquitin-like domain-containing protein.	Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase.	0.608
ENSSPAP00000000794	fignl1	ENSSPAP00000000794	ENSSPAP00000000832	Ubiquitin-like domain-containing protein.	Fidgetin-like 1; Belongs to the AAA ATPase family.	0.578
ENSSPAP00000000794	nploc4	ENSSPAP00000000794	ENSSPAP00000020866	Ubiquitin-like domain-containing protein.	NPL4 homolog, ubiquitin recognition factor.	0.945
ENSSPAP00000000794	pex1	ENSSPAP00000000794	ENSSPAP00000021705	Ubiquitin-like domain-containing protein.	Peroxisomal biogenesis factor 1.	0.734
ENSSPAP00000000794	pex6	ENSSPAP00000000794	ENSSPAP00000000114	Ubiquitin-like domain-containing protein.	Peroxisomal biogenesis factor 6.	0.734
ENSSPAP00000000794	plaa	ENSSPAP00000000794	ENSSPAP00000025115	Ubiquitin-like domain-containing protein.	Phospholipase A2-activating protein.	0.859
ENSSPAP00000000794	rnf145	ENSSPAP00000000794	ENSSPAP00000006011	Ubiquitin-like domain-containing protein.	Ring finger protein 145b.	0.608