(11 nodes) Mixed, incl. Mre11 complex, and DNA damage induced protein phosphorylation network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000003155	FHA domain-containing protein. (75 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2496 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
	bard1	BRCA1 associated RING domain 1. (814 aa)
	ENSSPAP00000006942	ANK_REP_REGION domain-containing protein. (352 aa)
	topbp1	DNA topoisomerase II binding protein 1. (1518 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1382 aa)
	atm	Non-specific serine/threonine protein kinase. (3048 aa)
	mdc1	Uncharacterized protein. (2005 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1561 aa)
	ENSSPAP00000030409	Uncharacterized protein. (174 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000003155	ENSSPAP00000006942	ENSSPAP00000003155	ENSSPAP00000006942	FHA domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.998
ENSSPAP00000003155	ENSSPAP00000030409	ENSSPAP00000003155	ENSSPAP00000030409	FHA domain-containing protein.	Uncharacterized protein.	0.885
ENSSPAP00000003155	atm	ENSSPAP00000003155	ENSSPAP00000022487	FHA domain-containing protein.	Non-specific serine/threonine protein kinase.	0.996
ENSSPAP00000003155	atr	ENSSPAP00000003155	ENSSPAP00000003683	FHA domain-containing protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.979
ENSSPAP00000003155	bard1	ENSSPAP00000003155	ENSSPAP00000005852	FHA domain-containing protein.	BRCA1 associated RING domain 1.	0.989
ENSSPAP00000003155	mdc1	ENSSPAP00000003155	ENSSPAP00000022912	FHA domain-containing protein.	Uncharacterized protein.	0.969
ENSSPAP00000003155	mre11	ENSSPAP00000003155	ENSSPAP00000003869	FHA domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.999
ENSSPAP00000003155	rad50	ENSSPAP00000003155	ENSSPAP00000015783	FHA domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.999
ENSSPAP00000003155	topbp1	ENSSPAP00000003155	ENSSPAP00000011447	FHA domain-containing protein.	DNA topoisomerase II binding protein 1.	0.932
ENSSPAP00000003155	tp53bp1	ENSSPAP00000003155	ENSSPAP00000030210	FHA domain-containing protein.	Tumor protein p53 binding protein, 1.	0.903
ENSSPAP00000006942	ENSSPAP00000003155	ENSSPAP00000006942	ENSSPAP00000003155	ANK_REP_REGION domain-containing protein.	FHA domain-containing protein.	0.998
ENSSPAP00000006942	ENSSPAP00000030409	ENSSPAP00000006942	ENSSPAP00000030409	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.735
ENSSPAP00000006942	atm	ENSSPAP00000006942	ENSSPAP00000022487	ANK_REP_REGION domain-containing protein.	Non-specific serine/threonine protein kinase.	0.994
ENSSPAP00000006942	atr	ENSSPAP00000006942	ENSSPAP00000003683	ANK_REP_REGION domain-containing protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.998
ENSSPAP00000006942	bard1	ENSSPAP00000006942	ENSSPAP00000005852	ANK_REP_REGION domain-containing protein.	BRCA1 associated RING domain 1.	0.999
ENSSPAP00000006942	mdc1	ENSSPAP00000006942	ENSSPAP00000022912	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.955
ENSSPAP00000006942	mre11	ENSSPAP00000006942	ENSSPAP00000003869	ANK_REP_REGION domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.993
ENSSPAP00000006942	rad50	ENSSPAP00000006942	ENSSPAP00000015783	ANK_REP_REGION domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.992
ENSSPAP00000006942	topbp1	ENSSPAP00000006942	ENSSPAP00000011447	ANK_REP_REGION domain-containing protein.	DNA topoisomerase II binding protein 1.	0.438
ENSSPAP00000006942	tp53bp1	ENSSPAP00000006942	ENSSPAP00000030210	ANK_REP_REGION domain-containing protein.	Tumor protein p53 binding protein, 1.	0.973