(10 nodes) Smc5-Smc6 complex, and FYN-binding protein 1/2-like network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000004194	hSH3 domain-containing protein. (113 aa)
	smc5	Structural maintenance of chromosomes 5. (1075 aa)
	ENSSPAP00000012558	Uncharacterized protein. (230 aa)
	nsmce4a	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (351 aa)
	smc6	Si:dkey-119f1.1. (1088 aa)
	nsmce1	NSE1 homolog, SMC5-SMC6 complex component. (244 aa)
	LOC103369152	Calcyon neuron-specific vesicular protein. (180 aa)
	LOC103364213	Structural maintenance of chromosomes 6. (896 aa)
	LOC103361533	Necdin-like 2. (269 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004194	LOC103364213	ENSSPAP00000004194	ENSSPAP00000025294	hSH3 domain-containing protein.	Structural maintenance of chromosomes 6.	0.946
ENSSPAP00000004194	LOC103369152	ENSSPAP00000004194	ENSSPAP00000017814	hSH3 domain-containing protein.	Calcyon neuron-specific vesicular protein.	0.957
ENSSPAP00000004194	nsmce1	ENSSPAP00000004194	ENSSPAP00000017783	hSH3 domain-containing protein.	NSE1 homolog, SMC5-SMC6 complex component.	0.957
ENSSPAP00000004194	nsmce2	ENSSPAP00000004194	ENSSPAP00000029088	hSH3 domain-containing protein.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.974
ENSSPAP00000004194	nsmce4a	ENSSPAP00000004194	ENSSPAP00000014224	hSH3 domain-containing protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.976
ENSSPAP00000004194	smc5	ENSSPAP00000004194	ENSSPAP00000009826	hSH3 domain-containing protein.	Structural maintenance of chromosomes 5.	0.975
ENSSPAP00000004194	smc6	ENSSPAP00000004194	ENSSPAP00000015621	hSH3 domain-containing protein.	Si:dkey-119f1.1.	0.946
ENSSPAP00000012558	LOC103364213	ENSSPAP00000012558	ENSSPAP00000025294	Uncharacterized protein.	Structural maintenance of chromosomes 6.	0.946
ENSSPAP00000012558	LOC103369152	ENSSPAP00000012558	ENSSPAP00000017814	Uncharacterized protein.	Calcyon neuron-specific vesicular protein.	0.957
ENSSPAP00000012558	nsmce1	ENSSPAP00000012558	ENSSPAP00000017783	Uncharacterized protein.	NSE1 homolog, SMC5-SMC6 complex component.	0.957
ENSSPAP00000012558	nsmce2	ENSSPAP00000012558	ENSSPAP00000029088	Uncharacterized protein.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.974
ENSSPAP00000012558	nsmce4a	ENSSPAP00000012558	ENSSPAP00000014224	Uncharacterized protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.976
ENSSPAP00000012558	smc5	ENSSPAP00000012558	ENSSPAP00000009826	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.975
ENSSPAP00000012558	smc6	ENSSPAP00000012558	ENSSPAP00000015621	Uncharacterized protein.	Si:dkey-119f1.1.	0.946
LOC103361533	LOC103364213	ENSSPAP00000028077	ENSSPAP00000025294	Necdin-like 2.	Structural maintenance of chromosomes 6.	0.986
LOC103361533	LOC103369152	ENSSPAP00000028077	ENSSPAP00000017814	Necdin-like 2.	Calcyon neuron-specific vesicular protein.	0.957
LOC103361533	nsmce1	ENSSPAP00000028077	ENSSPAP00000017783	Necdin-like 2.	NSE1 homolog, SMC5-SMC6 complex component.	0.999
LOC103361533	nsmce2	ENSSPAP00000028077	ENSSPAP00000029088	Necdin-like 2.	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.	0.999
LOC103361533	nsmce4a	ENSSPAP00000028077	ENSSPAP00000014224	Necdin-like 2.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.999
LOC103361533	smc5	ENSSPAP00000028077	ENSSPAP00000009826	Necdin-like 2.	Structural maintenance of chromosomes 5.	0.999