(46 nodes) Interconversion of nucleotide di- and triphosphates, and Uridine-diphosphatase activity network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103359905	Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. (429 aa)
	entpd2	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family. (502 aa)
	hddc3	HD domain containing 3. (179 aa)
	tpk1	Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (252 aa)
	ak7	Adenylate kinase 7b. (652 aa)
	glrx2	Glutaredoxin 2. (172 aa)
	LOC103373425	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (734 aa)
	lgals3bp	SRCR domain-containing protein. (592 aa)
	cant1	Calcium activated nucleotidase 1a. (406 aa)
	ENSSPAP00000007545	Uncharacterized protein; Belongs to the adenylate kinase family. (205 aa)
	LOC103362858	Nucleoside diphosphate kinase. (152 aa)
	LOC103369008	Adenosine kinase a. (379 aa)
	ntpcr	Nucleoside-triphosphatase, cancer-related. (195 aa)
	ENSSPAP00000011439	Uncharacterized protein. (55 aa)
	lrguk	Leucine-rich repeats and guanylate kinase domain containing. (537 aa)
	LOC103369566	Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (427 aa)
	LOC103374909	Nucleoside diphosphate kinase. (153 aa)
	ENSSPAP00000013148	Uncharacterized protein; Belongs to the adenylate kinase family. (222 aa)
	entpd5	Ectonucleoside triphosphate diphosphohydrolase 5a; Belongs to the GDA1/CD39 NTPase family. (408 aa)
	nme3	Nucleoside diphosphate kinase. (169 aa)
	LOC103353421	Calcium activated nucleotidase 1b. (417 aa)
	LOC103364515	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
	ak9	Adenylate kinase 9. (1421 aa)
	ak6	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
	MANEAL	Mannosidase endo-alpha like. (256 aa)
	ENSSPAP00000016668	Uncharacterized protein. (184 aa)
	nme7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (374 aa)
	LOC103354127	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (588 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	LOC103364603	Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. (505 aa)
	nme5	NME/NM23 family member 5; Belongs to the NDK family. (230 aa)
	ak4	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (229 aa)
	LOC103363629	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa)
	entpd1	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (497 aa)
	ak8	Adenylate kinase 8; Belongs to the adenylate kinase family. (394 aa)
	nudt2	Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (149 aa)
	glrx	Glutaredoxin (thioltransferase). (106 aa)
	ak5	Adenylate kinase 5; Belongs to the adenylate kinase family. (303 aa)
	LOC103371613	Ribonucleotide reductase M2 b. (288 aa)
	ENTPD7	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (598 aa)
	ak1	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (193 aa)
	entpd4	Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (618 aa)
	entpd3	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (589 aa)
	thtpa	Thiamine triphosphatase. (248 aa)
	ak2	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (249 aa)
	LOC103371580	NDK domain-containing protein; Belongs to the NDK family. (149 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000007545	ENSSPAP00000011439	ENSSPAP00000007545	ENSSPAP00000011439	Uncharacterized protein; Belongs to the adenylate kinase family.	Uncharacterized protein.	0.565
ENSSPAP00000007545	ENSSPAP00000016668	ENSSPAP00000007545	ENSSPAP00000016668	Uncharacterized protein; Belongs to the adenylate kinase family.	Uncharacterized protein.	0.699
ENSSPAP00000007545	ENTPD7	ENSSPAP00000007545	ENSSPAP00000026569	Uncharacterized protein; Belongs to the adenylate kinase family.	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family.	0.539
ENSSPAP00000007545	LOC103353421	ENSSPAP00000007545	ENSSPAP00000014162	Uncharacterized protein; Belongs to the adenylate kinase family.	Calcium activated nucleotidase 1b.	0.529
ENSSPAP00000007545	LOC103354127	ENSSPAP00000007545	ENSSPAP00000017119	Uncharacterized protein; Belongs to the adenylate kinase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.677
ENSSPAP00000007545	LOC103359905	ENSSPAP00000007545	ENSSPAP00000000859	Uncharacterized protein; Belongs to the adenylate kinase family.	Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family.	0.543
ENSSPAP00000007545	LOC103362858	ENSSPAP00000007545	ENSSPAP00000008626	Uncharacterized protein; Belongs to the adenylate kinase family.	Nucleoside diphosphate kinase.	0.813
ENSSPAP00000007545	LOC103363629	ENSSPAP00000007545	ENSSPAP00000021327	Uncharacterized protein; Belongs to the adenylate kinase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.677
ENSSPAP00000007545	LOC103364515	ENSSPAP00000007545	ENSSPAP00000014588	Uncharacterized protein; Belongs to the adenylate kinase family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.835
ENSSPAP00000007545	LOC103364603	ENSSPAP00000007545	ENSSPAP00000017493	Uncharacterized protein; Belongs to the adenylate kinase family.	Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family.	0.669
ENSSPAP00000007545	LOC103369008	ENSSPAP00000007545	ENSSPAP00000008832	Uncharacterized protein; Belongs to the adenylate kinase family.	Adenosine kinase a.	0.745
ENSSPAP00000007545	LOC103369566	ENSSPAP00000007545	ENSSPAP00000012288	Uncharacterized protein; Belongs to the adenylate kinase family.	Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family.	0.524
ENSSPAP00000007545	LOC103371580	ENSSPAP00000007545	ENSSPAP00000030678	Uncharacterized protein; Belongs to the adenylate kinase family.	NDK domain-containing protein; Belongs to the NDK family.	0.764
ENSSPAP00000007545	LOC103371613	ENSSPAP00000007545	ENSSPAP00000026040	Uncharacterized protein; Belongs to the adenylate kinase family.	Ribonucleotide reductase M2 b.	0.804
ENSSPAP00000007545	LOC103373425	ENSSPAP00000007545	ENSSPAP00000005343	Uncharacterized protein; Belongs to the adenylate kinase family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.832
ENSSPAP00000007545	LOC103374909	ENSSPAP00000007545	ENSSPAP00000012626	Uncharacterized protein; Belongs to the adenylate kinase family.	Nucleoside diphosphate kinase.	0.829
ENSSPAP00000007545	MANEAL	ENSSPAP00000007545	ENSSPAP00000016658	Uncharacterized protein; Belongs to the adenylate kinase family.	Mannosidase endo-alpha like.	0.699
ENSSPAP00000007545	ak1	ENSSPAP00000007545	ENSSPAP00000027107	Uncharacterized protein; Belongs to the adenylate kinase family.	Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.	0.814
ENSSPAP00000007545	ak2	ENSSPAP00000007545	ENSSPAP00000030599	Uncharacterized protein; Belongs to the adenylate kinase family.	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	0.877
ENSSPAP00000007545	ak4	ENSSPAP00000007545	ENSSPAP00000020145	Uncharacterized protein; Belongs to the adenylate kinase family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.857