STRINGSTRING
EIF4ENIF1 EIF4ENIF1 ythdf2 ythdf2 lsm2 lsm2 edc4 edc4 CNOT9 CNOT9 LOC103360139 LOC103360139 polr2g polr2g LOC103354577 LOC103354577 LOC103361861 LOC103361861 ENSSPAP00000019704 ENSSPAP00000019704 pan3 pan3 rc3h1 rc3h1 LOC103366440 LOC103366440 caprin1 caprin1 LOC103360126 LOC103360126 polr2d polr2d tnrc6a tnrc6a LOC103364512 LOC103364512 LOC103364453 LOC103364453 LOC103360817 LOC103360817 LOC103354115 LOC103354115 zc3h12a zc3h12a ENSSPAP00000015968 ENSSPAP00000015968 LOC103366853 LOC103366853 mex3b mex3b trim71 trim71 lsm4 lsm4 UPF1 UPF1 LOC103375326 LOC103375326 BTBD1 BTBD1 LOC103375937 LOC103375937 LOC103355155 LOC103355155 LOC103370183 LOC103370183 c9orf72 c9orf72 LOC103357815 LOC103357815 ENSSPAP00000011494 ENSSPAP00000011494 ajuba ajuba LOC103360073 LOC103360073 nanos3 nanos3 cnot8 cnot8 samd4a samd4a LOC103353462 LOC103353462 LOC103374096 LOC103374096 cnot2 cnot2 ENSSPAP00000008883 ENSSPAP00000008883 LOC103358936 LOC103358936 dcp1a dcp1a rc3h2 rc3h2 patl2 patl2 ENSSPAP00000006210 ENSSPAP00000006210 LOC103363883 LOC103363883 LOC103368395 LOC103368395 igf2bp3 igf2bp3 LOC103368936 LOC103368936 cnot3 cnot3 YTHDF1 YTHDF1 LOC103363318 LOC103363318 dcps dcps patl1 patl1 ENSSPAP00000004195 ENSSPAP00000004195 kiaa0355 kiaa0355 lsm14a lsm14a LOC103356046 LOC103356046 LOC103368876 LOC103368876 LOC103373921 LOC103373921 LOC103366045 LOC103366045 ythdf3 ythdf3 LOC103366028 LOC103366028 psma6 psma6 lsm3 lsm3 LOC103374481 LOC103374481 LOC103364873 LOC103364873 psmc2 psmc2 LOC103367511 LOC103367511 noct noct LOC103365993 LOC103365993 ddx6 ddx6 AGO4 AGO4 wtip wtip LOC103363773 LOC103363773 hax1 hax1 samd4b samd4b aicda aicda dis3l2 dis3l2 LOC103365891 LOC103365891 LOC103374411 LOC103374411 ybx1 ybx1 lsm1 lsm1 pnrc2 pnrc2 edc3 edc3 LOC103376164 LOC103376164 pan2 pan2 LOC103368117 LOC103368117 ago2 ago2 sqstm1 sqstm1 LOC103367053 LOC103367053 LOC103356992 LOC103356992 LOC103367052 LOC103367052 CNOT7 CNOT7 cnot1 cnot1 LOC103360971 LOC103360971 psma2 psma2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (960 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (638 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
edc4Enhancer of mRNA decapping 4. (1390 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
LOC103360139Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (876 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (171 aa)
LOC103354577YTH N(6)-methyladenosine RNA binding protein 1. (623 aa)
LOC103361861Trinucleotide repeat containing adaptor 6C1. (1839 aa)
ENSSPAP00000019704Decapping mRNA 2. (248 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (793 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1136 aa)
LOC103366440NOT2_3_5 domain-containing protein. (536 aa)
caprin1Cell cycle associated protein 1b. (714 aa)
LOC103360126Uncharacterized protein; Belongs to the DEAD box helicase family. (489 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
tnrc6aTrinucleotide repeat containing adaptor 6A. (1791 aa)
LOC103364512Trinucleotide repeat containing adaptor 6C2. (1892 aa)
LOC103364453Proteasome subunit alpha type. (261 aa)
LOC103360817Argonaute RISC component 4. (252 aa)
LOC103354115Lin-28 homolog A. (202 aa)
zc3h12aZinc finger CCCH-type containing 12A. (621 aa)
ENSSPAP00000015968RING-type domain-containing protein. (522 aa)
LOC103366853CCR4-NOT transcription complex, subunit 7. (248 aa)
mex3bMex-3 RNA binding family member B. (542 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (831 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa)
UPF1UPF1 RNA helicase and ATPase. (1100 aa)
LOC103375326Endo/exonuclease/phosphatase domain-containing protein. (367 aa)
BTBD1BTB domain containing 1. (488 aa)
LOC103375937Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
LOC103355155Uncharacterized protein. (562 aa)
LOC103370183RRM domain-containing protein. (79 aa)
c9orf72Zgc:100846. (462 aa)
LOC103357815Zgc:153119. (306 aa)
ENSSPAP00000011494Uncharacterized protein. (117 aa)
ajubaAjuba LIM protein. (730 aa)
LOC103360073Insulin-like growth factor 2 mRNA binding protein 1. (592 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (216 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
samd4aSterile alpha motif domain containing 4A. (604 aa)
LOC103353462DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (597 aa)
LOC103374096WT1 interacting protein. (679 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (451 aa)
ENSSPAP00000008883Uncharacterized protein. (58 aa)
LOC103358936Proteasome subunit alpha type. (246 aa)
dcp1aDecapping mRNA 1A. (506 aa)
rc3h2Ring finger and CCCH-type domains 2. (1156 aa)
patl2PAT1 homolog 2. (625 aa)
ENSSPAP00000006210Uncharacterized protein. (109 aa)
LOC103363883RNA binding protein, mRNA processing factor. (165 aa)
LOC103368395TNRC6-PABC_bdg domain-containing protein. (2144 aa)
igf2bp3Insulin-like growth factor 2 mRNA binding protein 3. (554 aa)
LOC103368936Nanos homolog 2; Belongs to the nanos family. (155 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (891 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (618 aa)
LOC103363318CCR4-NOT transcription complex subunit 9. (297 aa)
dcpsDecapping enzyme, scavenger. (330 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (752 aa)
ENSSPAP00000004195LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
kiaa0355Si:ch211-79l17.1. (1116 aa)
lsm14aLSM14A mRNA processing body assembly factor b. (453 aa)
LOC103356046Mov10 RISC complex RNA helicase a. (999 aa)
LOC103368876Proteasome subunit alpha type. (261 aa)
LOC103373921DEAD (Asp-Glu-Ala-Asp) box helicase 61; Belongs to the DEAD box helicase family. (484 aa)
LOC103366045CCR4-NOT transcription complex, subunit 3b. (929 aa)
ythdf3YTH N(6)-methyladenosine RNA binding protein 3. (606 aa)
LOC103366028DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (604 aa)
psma6Proteasome subunit alpha type. (246 aa)
lsm3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
LOC103374481Insulin-like growth factor 2 mRNA binding protein 2a. (534 aa)
LOC103364873Proteasome subunit alpha type. (246 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
LOC103367511Uncharacterized protein. (1076 aa)
noctNocturnin. (465 aa)
LOC103365993LSM14A mRNA processing body assembly factor a. (438 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
AGO4Argonaute RISC component 4. (442 aa)
wtipUncharacterized protein. (616 aa)
LOC103363773CCHC-type zinc finger, nucleic acid binding protein b. (138 aa)
hax1HCLS1 associated protein X-1. (306 aa)
samd4bSterile alpha motif domain containing 4B. (671 aa)
aicdaActivation-induced cytidine deaminase. (316 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1052 aa)
LOC103365891DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (755 aa)
LOC103374411Si:dkey-206d17.12. (601 aa)
ybx1Y box binding protein 1. (324 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
pnrc2Proline-rich nuclear receptor coactivator 2. (159 aa)
edc3Enhancer of mRNA decapping 3. (474 aa)
LOC103376164BTB (POZ) domain containing 2b. (575 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
LOC103368117Si:dkey-46g23.1. (2066 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (875 aa)
sqstm1Sequestosome 1. (415 aa)
LOC103367053Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103356992Cell cycle associated protein 1a. (630 aa)
LOC103367052Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (249 aa)
cnot1CCR4-NOT transcription complex, subunit 1. (2333 aa)
LOC103360971Moloney leukemia virus 10b, tandem duplicate 1. (999 aa)
psma2Proteasome subunit alpha type. (234 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.