STRINGSTRING
exosc5 exosc5 arsk arsk rc3h2 rc3h2 exosc3 exosc3 mtpap mtpap patl2 patl2 ssb ssb ENSSPAP00000007455 ENSSPAP00000007455 dcp1a dcp1a ENSSPAP00000008883 ENSSPAP00000008883 cnot2 cnot2 LOC103363970 LOC103363970 LOC103363971 LOC103363971 exosc10 exosc10 LOC103366231 LOC103366231 samd4a samd4a cnot8 cnot8 mrto4 mrto4 upf3a upf3a ENSSPAP00000010665 ENSSPAP00000010665 ENSSPAP00000010685 ENSSPAP00000010685 ENSSPAP00000010739 ENSSPAP00000010739 magoh magoh pelo pelo ENSSPAP00000011494 ENSSPAP00000011494 smg7 smg7 zfp36l2 zfp36l2 DXO DXO LOC103355155 LOC103355155 upf3b upf3b LOC103375937 LOC103375937 zfp36l1 zfp36l1 ENSSPAP00000013853 ENSSPAP00000013853 mettl16 mettl16 LOC103375326 LOC103375326 UPF1 UPF1 lsm4 lsm4 LOC103366853 LOC103366853 rbm8a rbm8a zc3h12a zc3h12a NCBP1 NCBP1 supv3l1 supv3l1 skiv2l skiv2l polr2d polr2d tbp tbp mettl3 mettl3 LOC103361824 LOC103361824 LOC103366440 LOC103366440 smg5 smg5 ENSSPAP00000018995 ENSSPAP00000018995 nudt12 nudt12 LOC103366045 LOC103366045 exosc6 exosc6 swt1 swt1 smg1 smg1 cnot6 cnot6 LOC103367511 LOC103367511 nbas nbas mlh1 mlh1 samd4b samd4b ncbp2 ncbp2 rc3h1 rc3h1 cnot10 cnot10 pan3 pan3 noct noct ENSSPAP00000019704 ENSSPAP00000019704 smg9 smg9 pde12 pde12 RIDA RIDA lsm7 lsm7 polr2g polr2g LOC103358589 LOC103358589 smg6 smg6 LOC103360139 LOC103360139 CNOT9 CNOT9 xrn2 xrn2 LOC103374411 LOC103374411 exosc4 exosc4 edc4 edc4 etf1 etf1 lsm2 lsm2 casc3 casc3 exosc2 exosc2 cnot6l cnot6l ENSSPAP00000030471 ENSSPAP00000030471 smg8 smg8 PNPT1 PNPT1 atm atm eif4a3 eif4a3 ythdf2 ythdf2 LOC103372505 LOC103372505 ENSSPAP00000024273 ENSSPAP00000024273 ENSSPAP00000024293 ENSSPAP00000024293 lrrc27 lrrc27 snd1 snd1 dis3l2 dis3l2 ENSSPAP00000024373 ENSSPAP00000024373 cnot1 cnot1 CNOT7 CNOT7 LOC103367052 LOC103367052 LOC103367053 LOC103367053 LOC103371553 LOC103371553 ago2 ago2 pan2 pan2 pym1 pym1 edc3 edc3 pnrc2 pnrc2 lsm1 lsm1 zcchc7 zcchc7 exosc8 exosc8 LOC103363318 LOC103363318 helz2 helz2 ctif ctif cnot3 cnot3 LOC103368936 LOC103368936 exosc9 exosc9 exosc7 exosc7 dcps dcps patl1 patl1 ENSSPAP00000004195 ENSSPAP00000004195 cnot11 cnot11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
exosc5Exosome component 5. (220 aa)
arskTetratricopeptide repeat domain 37. (1582 aa)
rc3h2Ring finger and CCCH-type domains 2. (1156 aa)
exosc3Exosome component 3. (244 aa)
mtpapMitochondrial poly(A) polymerase. (576 aa)
patl2PAT1 homolog 2. (625 aa)
ssbSmall RNA binding exonuclease protection factor La. (384 aa)
ENSSPAP00000007455Uncharacterized protein. (144 aa)
dcp1aDecapping mRNA 1A. (506 aa)
ENSSPAP00000008883Uncharacterized protein. (58 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (451 aa)
LOC103363970Zgc:162730. (425 aa)
LOC103363971Zgc:114130. (434 aa)
exosc10Exosome component 10. (892 aa)
LOC103366231Poly(A)-specific ribonuclease (deadenylation nuclease). (682 aa)
samd4aSterile alpha motif domain containing 4A. (604 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (240 aa)
upf3aUPF3A regulator of nonsense mediated mRNA decay. (477 aa)
ENSSPAP00000010665Uncharacterized protein. (146 aa)
ENSSPAP00000010685Uncharacterized protein. (143 aa)
ENSSPAP00000010739Uncharacterized protein. (641 aa)
magohMago homolog, exon junction complex subunit. (147 aa)
peloProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
ENSSPAP00000011494Uncharacterized protein. (117 aa)
smg7SMG7 nonsense mediated mRNA decay factor. (1122 aa)
zfp36l2Zinc finger protein 36, C3H type-like 2. (430 aa)
DXODecapping exoribonuclease. (426 aa)
LOC103355155Uncharacterized protein. (562 aa)
upf3bUPF3B regulator of nonsense mediated mRNA decay. (457 aa)
LOC103375937Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (372 aa)
ENSSPAP00000013853Upf2 domain-containing protein. (252 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (556 aa)
LOC103375326Endo/exonuclease/phosphatase domain-containing protein. (367 aa)
UPF1UPF1 RNA helicase and ATPase. (1100 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (151 aa)
LOC103366853CCR4-NOT transcription complex, subunit 7. (248 aa)
rbm8aRNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (175 aa)
zc3h12aZinc finger CCCH-type containing 12A. (621 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
supv3l1SUV3-like helicase. (758 aa)
skiv2lSKI2 homolog, superkiller viralicidic activity 2-like. (1188 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
tbpTATA box binding protein. (309 aa)
mettl3Methyltransferase like 3; Belongs to the MT-A70-like family. (591 aa)
LOC103361824Sb:cb81. (397 aa)
LOC103366440NOT2_3_5 domain-containing protein. (536 aa)
smg5SMG5 nonsense mediated mRNA decay factor. (1128 aa)
ENSSPAP00000018995MIF4G domain-containing protein. (373 aa)
nudt12Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (459 aa)
LOC103366045CCR4-NOT transcription complex, subunit 3b. (929 aa)
exosc6Exosome component 6. (274 aa)
swt1SWT1 RNA endoribonuclease homolog. (968 aa)
smg1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3607 aa)
cnot6CCR4-NOT transcription complex, subunit 6a. (559 aa)
LOC103367511Uncharacterized protein. (1076 aa)
nbasNeuroblastoma amplified sequence. (1975 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (738 aa)
samd4bSterile alpha motif domain containing 4B. (671 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (175 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1136 aa)
cnot10CCR4-NOT transcription complex, subunit 10. (755 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (793 aa)
noctNocturnin. (465 aa)
ENSSPAP00000019704Decapping mRNA 2. (248 aa)
smg9SMG9 nonsense mediated mRNA decay factor. (508 aa)
pde12Phosphodiesterase 12. (591 aa)
RIDAReactive intermediate imine deaminase A homolog. (136 aa)
lsm7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (167 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (171 aa)
LOC103358589Uncharacterized protein. (491 aa)
smg6SMG6 nonsense mediated mRNA decay factor. (1647 aa)
LOC103360139Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (876 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (971 aa)
LOC103374411Si:dkey-206d17.12. (601 aa)
exosc4Exosome component 4. (264 aa)
edc4Enhancer of mRNA decapping 4. (1390 aa)
etf1Eukaryotic translation termination factor 1b. (443 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
casc3Casc3 exon junction complex subunit. (766 aa)
exosc2Exosome component 2. (293 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (553 aa)
ENSSPAP00000030471Uncharacterized protein. (111 aa)
smg8SMG8 nonsense mediated mRNA decay factor. (923 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (770 aa)
atmNon-specific serine/threonine protein kinase. (3048 aa)
eif4a3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (410 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (638 aa)
LOC103372505Tudor domain-containing protein. (183 aa)
ENSSPAP00000024273C2H2-type domain-containing protein. (151 aa)
ENSSPAP00000024293Uncharacterized protein. (148 aa)
lrrc27Uncharacterized protein. (428 aa)
snd1Staphylococcal nuclease and tudor domain containing 1. (641 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1052 aa)
ENSSPAP00000024373Uncharacterized protein. (701 aa)
cnot1CCR4-NOT transcription complex, subunit 1. (2333 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (249 aa)
LOC103367052Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
LOC103367053Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103371553Reactive intermediate imine deaminase A homolog. (135 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (875 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
pym1PYM homolog 1, exon junction complex associated factor. (214 aa)
edc3Enhancer of mRNA decapping 3. (474 aa)
pnrc2Proline-rich nuclear receptor coactivator 2. (159 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
zcchc7Zinc finger, CCHC domain containing 7. (663 aa)
exosc8Exosome component 8. (277 aa)
LOC103363318CCR4-NOT transcription complex subunit 9. (297 aa)
helz2C3H1-type domain-containing protein. (2910 aa)
ctifCBP80/20-dependent translation initiation factor. (584 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (891 aa)
LOC103368936Nanos homolog 2; Belongs to the nanos family. (155 aa)
exosc9Exosome component 9. (420 aa)
exosc7Exosome component 7. (291 aa)
dcpsDecapping enzyme, scavenger. (330 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (752 aa)
ENSSPAP00000004195LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
cnot11CCR4-NOT transcription complex, subunit 11. (445 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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