STRINGSTRING
LOC103362358 LOC103362358 LOC103363373 LOC103363373 nf1 nf1 mecp2 mecp2 LOC103358913 LOC103358913 LOC103358915 LOC103358915 LOC103355037 LOC103355037 LOC103366454 LOC103366454 ENSSPAP00000007333 ENSSPAP00000007333 LOC103366706 LOC103366706 LOC103360654 LOC103360654 sirt1 sirt1 angpt2 angpt2 LOC103374663 LOC103374663 LOC103370644 LOC103370644 LOC103374198 LOC103374198 LOC103359516 LOC103359516 ENSSPAP00000009713 ENSSPAP00000009713 LOC103371190 LOC103371190 LOC103365633 LOC103365633 reck reck LOC103374411 LOC103374411 mst1r mst1r fgf4 fgf4 LOC103362006 LOC103362006 vegfa vegfa efna1 efna1 bmpr2 bmpr2 mmrn2 mmrn2 LOC103373263 LOC103373263 sp1 sp1 LOC103370974 LOC103370974 LOC103368234 LOC103368234 LOC103368235 LOC103368235 bmper bmper LOC103359878 LOC103359878 LOC103365994 LOC103365994 ENSSPAP00000031321 ENSSPAP00000031321 sash1 sash1 fgf2 fgf2 plcg2 plcg2 vash2 vash2 ARSB ARSB LOC103368571 LOC103368571 met met LOC103361652 LOC103361652 bmp10 bmp10 LOC103368399 LOC103368399 TGFBR2 TGFBR2 mcc mcc LOC103356681 LOC103356681 gpi gpi LOC103360542 LOC103360542 mtor mtor itgb1bp1 itgb1bp1 LOC103368896 LOC103368896 ENSSPAP00000003415 ENSSPAP00000003415 glipr2 glipr2 tbxa2r tbxa2r rreb1 rreb1 igf2 igf2 LOC103365438 LOC103365438 GATA2 GATA2 LOC103372209 LOC103372209 ENSSPAP00000001400 ENSSPAP00000001400 plcg1 plcg1 LOC103372191 LOC103372191 ATP5F1A ATP5F1A LOC103354964 LOC103354964 ARF6 ARF6 tgfbr2 tgfbr2 LOC103358766 LOC103358766 LOC103369128 LOC103369128 fgf1 fgf1 zc3h12a zc3h12a LOC103359141 LOC103359141 meox2 meox2 fgf16 fgf16 LOC103358541 LOC103358541 LOC103364060 LOC103364060 LOC103374289 LOC103374289 ctsh ctsh ptk2b ptk2b ENSSPAP00000019170 ENSSPAP00000019170 ENSSPAP00000019452 ENSSPAP00000019452 LOC103357988 LOC103357988 cib1 cib1 RIN2 RIN2 LOC103376433 LOC103376433 nrp1 nrp1 tgfb2 tgfb2 lgmn lgmn capn7 capn7 dusp10 dusp10 LOC103359300 LOC103359300 tsta3 tsta3 ENSSPAP00000023532 ENSSPAP00000023532 LOC103363690 LOC103363690 pdgfb pdgfb LOC103362533 LOC103362533 LOC103371395 LOC103371395 bsg bsg LOC103372548 LOC103372548 ptprg ptprg LOC103370848 LOC103370848 map2k5 map2k5 LOC103364206 LOC103364206 fgf7 fgf7 LOC103360420 LOC103360420 card10 card10 arsi arsi nfe2l2 nfe2l2 VASH1 VASH1 pik3cg pik3cg LOC103369070 LOC103369070 ptpn23 ptpn23 LOC103354591 LOC103354591 LOC103359554 LOC103359554 LOC103375280 LOC103375280 angpt1 angpt1 LOC103356766 LOC103356766 LOC103363473 LOC103363473 ENSSPAP00000014533 ENSSPAP00000014533 aamp aamp LOC103363938 LOC103363938 agt agt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103362358RAB25, member RAS oncogene family b. (208 aa)
LOC103363373Si:dkey-175m17.7. (872 aa)
nf1Neurofibromin 1b. (2780 aa)
mecp2Methyl CpG binding protein 2. (974 aa)
LOC1033589131-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
LOC103358915Si:ch211-191a24.4. (289 aa)
LOC103355037ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (518 aa)
LOC103366454acidPPc domain-containing protein. (313 aa)
ENSSPAP00000007333Uncharacterized protein. (69 aa)
LOC103366706Glutamine synthetase. (371 aa)
LOC103360654SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (204 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (695 aa)
angpt2Angiopoietin 2a. (493 aa)
LOC103374663TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
LOC103370644CD40 molecule, TNF receptor superfamily member 5. (300 aa)
LOC103374198Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
LOC103359516BCAS3 microtubule associated cell migration factor. (711 aa)
ENSSPAP00000009713Arylsulfatase family, member J. (589 aa)
LOC103371190Angiopoietin 4. (524 aa)
LOC103365633Phospholipid phosphatase 3. (307 aa)
reckReversion-inducing-cysteine-rich protein with kazal motifs. (959 aa)
LOC103374411Si:dkey-206d17.12. (601 aa)
mst1rMacrophage stimulating 1 receptor b. (1369 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
LOC103362006Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1081 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (212 aa)
efna1Ephrin-A1b; Belongs to the ephrin family. (234 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
mmrn2EMI domain-containing protein. (1066 aa)
LOC103373263Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
sp1Sp1 transcription factor. (710 aa)
LOC103370974JunE proto-oncogene, AP-1 transcription factor subunit. (340 aa)
LOC103368234Uncharacterized protein. (364 aa)
LOC103368235Uncharacterized protein. (352 aa)
bmperBMP binding endothelial regulator. (726 aa)
LOC103359878GATA binding protein 2a. (459 aa)
LOC103365994Glucose-6-phosphate isomerase; Belongs to the GPI family. (502 aa)
ENSSPAP00000031321Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (305 aa)
sash1SAM and SH3 domain containing 1a. (1227 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
plcg2Phosphoinositide phospholipase C. (1088 aa)
vash2Vasohibin 2. (289 aa)
ARSBArylsulfatase B. (518 aa)
LOC103368571Glutamine synthetase. (373 aa)
metMET proto-oncogene, receptor tyrosine kinase. (1417 aa)
LOC103361652Bone morphogenetic protein 10, like. (459 aa)
bmp10Bone morphogenetic protein 10. (468 aa)
LOC103368399SH3-domain binding protein 1. (730 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
mccUsher syndrome 1C binding protein 1. (701 aa)
LOC103356681Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
gpiGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
LOC103360542ADAM metallopeptidase domain 17a. (876 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2514 aa)
itgb1bp1Integrin beta 1 binding protein 1. (198 aa)
LOC103368896Protein tyrosine kinase 2. (916 aa)
ENSSPAP00000003415Focal_AT domain-containing protein. (115 aa)
glipr2GLI pathogenesis-related 2, like; Belongs to the CRISP family. (156 aa)
tbxa2rThromboxane A2 receptor. (373 aa)
rreb1Ras responsive element binding protein 1a. (1730 aa)
igf2Insulin-like growth factor 2b. (215 aa)
LOC103365438Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1105 aa)
GATA2GATA binding protein 2. (455 aa)
LOC103372209Ras and Rab interactor 2. (1110 aa)
ENSSPAP00000001400Uncharacterized protein. (1302 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1313 aa)
LOC103372191Uncharacterized protein. (1298 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
LOC103354964Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (237 aa)
ARF6ADP ribosylation factor 6. (123 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (583 aa)
LOC103358766Ephrin-A1a; Belongs to the ephrin family. (227 aa)
LOC103369128Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1005 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
zc3h12aZinc finger CCCH-type containing 12A. (621 aa)
LOC103359141Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
meox2Mesenchyme homeobox 2a. (315 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC103358541Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (520 aa)
LOC103364060Angiopoietin 2b. (504 aa)
LOC103374289Uncharacterized protein; Belongs to the peptidase C1 family. (336 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (323 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (974 aa)
ENSSPAP00000019170Apolipoprotein Ea. (259 aa)
ENSSPAP00000019452Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (282 aa)
LOC103357988ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
RIN2Ras and Rab interactor 2. (962 aa)
LOC103376433RAB25, member RAS oncogene family a. (211 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (917 aa)
tgfb2Transforming growth factor, beta 2. (144 aa)
lgmnLegumain. (436 aa)
capn7Calpain 7; Belongs to the peptidase C2 family. (819 aa)
dusp10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
LOC103359300Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
tsta3Tissue specific transplantation antigen P35B. (326 aa)
ENSSPAP00000023532Macrophage stimulating 1 receptor b. (259 aa)
LOC103363690Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (202 aa)
pdgfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa)
LOC103362533Junction plakoglobin a. (729 aa)
LOC103371395ADAM metallopeptidase domain 17b. (836 aa)
bsgBasigin. (273 aa)
LOC103372548Sulfatase domain-containing protein. (771 aa)
ptprgCarbonic anhydrase XVI b. (1404 aa)
LOC103370848Si:dkey-174i8.1. (523 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
LOC103364206SAM and SH3 domain containing 1b. (950 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
LOC103360420Macrophage stimulating 1 receptor a. (1375 aa)
card10Uncharacterized protein. (1030 aa)
arsiArylsulfatase family, member Ia. (569 aa)
nfe2l2Nuclear factor, erythroid 2-like 2a. (613 aa)
VASH1Vasohibin 1. (335 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1123 aa)
LOC103369070Protein tyrosine phosphatase receptor type Z1b. (1284 aa)
ptpn23Protein tyrosine phosphatase, non-receptor type 23, a. (1960 aa)
LOC103354591ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
LOC103359554Uncharacterized protein. (750 aa)
LOC103375280Transforming growth factor beta; Belongs to the TGF-beta family. (333 aa)
angpt1Angiopoietin 1. (519 aa)
LOC103356766Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
LOC103363473Regulator of cell cycle. (126 aa)
ENSSPAP00000014533Uncharacterized protein. (111 aa)
aampAngio-associated, migratory cell protein. (418 aa)
LOC103363938Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
agtAngiotensinogen; Belongs to the serpin family. (463 aa)
Your Current Organism:
Stegastes partitus
NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish
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