(74 nodes) Positive regulation of cell-substrate adhesion network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	disc1	DISC1 scaffold protein. (848 aa)
	LOC103353988	LIM domain-containing protein. (405 aa)
	COL26A1	Collagen type XXVI alpha 1 chain. (440 aa)
	LOC103358424	Si:dkeyp-75h12.2. (685 aa)
	ENSSPAP00000012073	Si:ch211-173a9.6. (498 aa)
	LOC103355137	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (419 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (1000 aa)
	LOC103371890	Uncharacterized protein. (1226 aa)
	LOC103359554	Uncharacterized protein. (750 aa)
	ENSSPAP00000013124	Uncharacterized protein. (272 aa)
	LOC103363469	Coiled-coil domain containing 80. (838 aa)
	LOC103362295	Vitronectin b. (446 aa)
	LOC103372345	Elastin microfibril interfacer 1a. (1037 aa)
	fermt1	Fermitin family member 1. (611 aa)
	LOC103358541	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (520 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	LOC103356837	Uncharacterized protein. (191 aa)
	myoc	Myocilin. (482 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (189 aa)
	RIN2	Ras and Rab interactor 2. (962 aa)
	LOC103376046	Vitronectin a. (515 aa)
	spock2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (419 aa)
	ENSSPAP00000021010	Uncharacterized protein. (280 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (917 aa)
	ccn1	Cellular communication network factor 1. (380 aa)
	LOC103373710	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (138 aa)
	LOC103372064	Cell division cycle 42. (191 aa)
	ENSSPAP00000022040	Chemokine (C-C motif) ligand 25b. (99 aa)
	tsta3	Tissue specific transplantation antigen P35B. (326 aa)
	CDC42	Cell division cycle 42. (191 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	pdgfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa)
	LOC103368079	Uncharacterized protein. (703 aa)
	plekha2	Si:ch211-204d2.4. (412 aa)
	apoa4	Uncharacterized protein. (235 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	LOC103356278	Protein S100; Belongs to the S-100 family. (100 aa)
	LOC103371676	MARVEL domain-containing protein. (268 aa)
	rreb1	Ras responsive element binding protein 1a. (1730 aa)
	lrrc45	Leucine rich repeat containing 45. (597 aa)
	LOC103372209	Ras and Rab interactor 2. (1110 aa)
	LOC103359902	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (169 aa)
	vwc2	Von Willebrand factor C domain containing 2. (312 aa)
	LOC103366577	Fibronectin type-III domain-containing protein. (520 aa)
	LOC103365419	Uncharacterized protein. (315 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (396 aa)
	LOC103365935	Fibronectin 1a. (2478 aa)
	LOC103370997	Uncharacterized protein. (731 aa)
	LOC103362081	TSC complex subunit 1b. (1282 aa)
	ENSSPAP00000030434	Uncharacterized protein. (92 aa)
	dab2	DAB adaptor protein 2. (787 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (212 aa)
	ENSSPAP00000028883	Chondroitin sulfate proteoglycan 5b. (362 aa)
	ENSSPAP00000028200	Si:dkeyp-66d1.7. (294 aa)
	tesk2	Testis associated actin remodelling kinase 2. (531 aa)
	LOC103364230	Chondroitin sulfate proteoglycan 5a. (518 aa)
	ECM2	Extracellular matrix protein 2. (612 aa)
	CRK	CRK proto-oncogene, adaptor protein. (315 aa)
	rsu1	Ras suppressor protein 1. (277 aa)
	LOC103362533	Junction plakoglobin a. (729 aa)
	cass4	Cas scaffold protein family member 4. (811 aa)
	ENSSPAP00000004069	Si:ch211-194g2.4. (165 aa)
	LOC103372831	Elastin microfibril interfacer 1b. (1212 aa)
	c1qbp	Complement component 1, q subcomponent binding protein. (286 aa)
	LOC103354479	Uncharacterized protein. (452 aa)
	agr2	Anterior gradient 2. (195 aa)
	ENSSPAP00000006201	Si:dkey-32e6.6. (325 aa)
	LOC103368958	Neuron-derived neurotrophic factor, like. (575 aa)
	LOC103365967	Olfactomedin-like domain-containing protein. (460 aa)
	LOC103352838	LIM domain-containing protein. (343 aa)
	LOC103368433	Colony stimulating factor 1b (macrophage). (270 aa)
	ILK	Integrin linked kinase. (454 aa)
	egfl6	EGF-like-domain, multiple 6. (518 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	CRK	ENSSPAP00000022477	ENSSPAP00000025617	Cell division cycle 42.	CRK proto-oncogene, adaptor protein.	0.523
CDC42	ENSSPAP00000030434	ENSSPAP00000022477	ENSSPAP00000030434	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	ILK	ENSSPAP00000022477	ENSSPAP00000008836	Cell division cycle 42.	Integrin linked kinase.	0.474
CDC42	LOC103354479	ENSSPAP00000022477	ENSSPAP00000005584	Cell division cycle 42.	Uncharacterized protein.	0.474
CDC42	LOC103356837	ENSSPAP00000022477	ENSSPAP00000018484	Cell division cycle 42.	Uncharacterized protein.	0.817
CDC42	LOC103358424	ENSSPAP00000022477	ENSSPAP00000011978	Cell division cycle 42.	Si:dkeyp-75h12.2.	0.457
CDC42	LOC103359554	ENSSPAP00000022477	ENSSPAP00000013044	Cell division cycle 42.	Uncharacterized protein.	0.446
CDC42	LOC103362081	ENSSPAP00000022477	ENSSPAP00000030532	Cell division cycle 42.	TSC complex subunit 1b.	0.553
CDC42	LOC103362533	ENSSPAP00000022477	ENSSPAP00000024322	Cell division cycle 42.	Junction plakoglobin a.	0.446
CDC42	LOC103365419	ENSSPAP00000022477	ENSSPAP00000000316	Cell division cycle 42.	Uncharacterized protein.	0.523
CDC42	LOC103368079	ENSSPAP00000022477	ENSSPAP00000023820	Cell division cycle 42.	Uncharacterized protein.	0.553
CDC42	LOC103373710	ENSSPAP00000022477	ENSSPAP00000021289	Cell division cycle 42.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.613
CDC42	arl2	ENSSPAP00000022477	ENSSPAP00000022922	Cell division cycle 42.	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.	0.432
CDC42	c1qbp	ENSSPAP00000022477	ENSSPAP00000004822	Cell division cycle 42.	Complement component 1, q subcomponent binding protein.	0.430
CDC42	cass4	ENSSPAP00000022477	ENSSPAP00000004029	Cell division cycle 42.	Cas scaffold protein family member 4.	0.464
CDC42	cib1	ENSSPAP00000022477	ENSSPAP00000019839	Cell division cycle 42.	Calcium and integrin binding 1 (calmyrin).	0.417
CDC42	crkl	ENSSPAP00000022477	ENSSPAP00000019143	Cell division cycle 42.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.523
CDC42	fermt1	ENSSPAP00000022477	ENSSPAP00000015400	Cell division cycle 42.	Fermitin family member 1.	0.482
CDC42	lrrc45	ENSSPAP00000022477	ENSSPAP00000001641	Cell division cycle 42.	Leucine rich repeat containing 45.	0.659
CDC42	tesk2	ENSSPAP00000022477	ENSSPAP00000027953	Cell division cycle 42.	Testis associated actin remodelling kinase 2.	0.457