(96 nodes) Positive regulation of endopeptidase activity network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103374736	Coagulation factor IIIa. (287 aa)
	LOC103354964	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (237 aa)
	ENSSPAP00000000694	Asp_Arg_Hydrox domain-containing protein. (92 aa)
	ENSSPAP00000000890	PRELI/MSF1 domain-containing protein. (210 aa)
	ENSSPAP00000001077	Uncharacterized protein. (79 aa)
	LOC103369977	Uncharacterized protein. (197 aa)
	pdcd5	Programmed cell death 5. (125 aa)
	LOC103375115	Uncharacterized protein; Belongs to the peptidase C14A family. (497 aa)
	LOC103375119	Uncharacterized protein; Belongs to the peptidase C14A family. (295 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (582 aa)
	ENSSPAP00000002991	Proteasome activator subunit 3. (240 aa)
	tnfsf10	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (287 aa)
	ENSSPAP00000003871	Uncharacterized protein. (96 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (1108 aa)
	dap	Death-associated protein. (143 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (432 aa)
	LOC103369458	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (461 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	ENSSPAP00000018422	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
	ctsh	Cathepsin H; Belongs to the peptidase C1 family. (323 aa)
	TFAP4	BHLH domain-containing protein. (369 aa)
	LOC103354471	RPN13_C domain-containing protein. (413 aa)
	casp2	Uncharacterized protein; Belongs to the peptidase C14A family. (290 aa)
	LOC103354167	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (263 aa)
	vsir	V-set immunoregulatory receptor. (301 aa)
	fadd	Uncharacterized protein. (191 aa)
	psme1	Proteasome activator subunit 1. (250 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (464 aa)
	ENSSPAP00000028444	Uncharacterized protein. (104 aa)
	mbp	Myelin basic protein b. (137 aa)
	ENSSPAP00000028083	Uncharacterized protein. (221 aa)
	NCSTN	Nicastrin. (701 aa)
	LOC103376203	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (549 aa)
	LOC103355433	PRA1 family protein. (190 aa)
	LOC103357518	MALT paracaspase 3. (547 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (282 aa)
	LOC103371455	Homeobox protein Nkx-3.1-like. (192 aa)
	LOC103371952	Uncharacterized protein. (341 aa)
	LOC103376144	GRAM domain containing 4a. (617 aa)
	uaca	Uveal autoantigen with coiled-coil domains and ankyrin repeats b. (1388 aa)
	arl6ip5	PRA1 family protein. (191 aa)
	tfap4	Transcription factor AP-4 (activating enhancer binding protein 4). (339 aa)
	LOC103355982	Akirin 2. (182 aa)
	prelid1	PRELI domain containing 1a. (210 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	sox7	SRY-box transcription factor 7. (375 aa)
	LOC103365251	PRELI domain containing 1b. (235 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	LOC103367454	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family. (439 aa)
	malt1	MALT paracaspase 1. (831 aa)
	LOC103359156	Akirin 2. (209 aa)
	LOC103374289	Uncharacterized protein; Belongs to the peptidase C1 family. (336 aa)
	pdcd2	Programmed cell death 2. (366 aa)
	ENSSPAP00000017677	Nerve growth factor receptor a (TNFR superfamily, member 16). (289 aa)
	p2rx1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (421 aa)
	ENSSPAP00000016954	Uncharacterized protein. (763 aa)
	LOC103356807	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	prr7	Proline rich 7 (synaptic). (296 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	LOC103362330	NK3 homeobox 1. (192 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	hip1	Huntingtin interacting protein 1. (1031 aa)
	ENSSPAP00000013840	Asp-B-Hydro_N domain-containing protein. (353 aa)
	casp8ap2	Uncharacterized protein. (1838 aa)
	LOC103354574	GRAM domain-containing protein. (587 aa)
	USP50	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (376 aa)
	LOC103356718	Diablo, IAP-binding mitochondrial protein a. (234 aa)
	LOC103356717	Diablo, IAP-binding mitochondrial protein a. (261 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	ENSSPAP00000008247	CARD domain-containing protein. (112 aa)
	LOC103363939	Uncharacterized protein. (300 aa)
	LOC103356956	Tumor necrosis factor a (TNF superfamily, member 2). (244 aa)
	psme2	Proteasome activator subunit 2. (245 aa)
	pycard	PYD and CARD domain containing. (201 aa)
	hip1r	Huntingtin interacting protein 1 related b. (1050 aa)
	card9	CARD domain-containing protein. (180 aa)
	LOC103370918	Apoptosis inducing factor mitochondrion associated 1. (651 aa)
	LOC103371515	Uncharacterized protein. (492 aa)
	efna1	Ephrin-A1b; Belongs to the ephrin family. (234 aa)
	ENSSPAP00000021681	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	lgmn	Legumain. (436 aa)
	efna3	Ephrin-A3a; Belongs to the ephrin family. (223 aa)
	ENSSPAP00000029263	Uncharacterized protein. (118 aa)
	LOC103353832	RAD21 cohesin complex component a. (632 aa)
	LOC103357552	Zgc:153993. (205 aa)
	ccn1	Cellular communication network factor 1. (380 aa)
	LOC103355278	Establishment of sister chromatid cohesion N-acetyltransferase 2. (664 aa)
	LOC103365208	MALT paracaspase 2. (797 aa)
	LOC103356890	Mitochondrial E3 ubiquitin protein ligase 1a. (353 aa)
	LOC103376010	P53-induced death domain protein 1. (884 aa)
	cyfip2	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
	LOC103360880	Uncharacterized protein. (330 aa)
	ENSSPAP00000020133	Rad21_Rec8_N domain-containing protein. (154 aa)
	RAD21	RAD21 cohesin complex component. (624 aa)
	LOC103358766	Ephrin-A1a; Belongs to the ephrin family. (227 aa)
	LOC103356008	Adhesion regulating molecule 1. (413 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000002991	LOC103354471	ENSSPAP00000002991	ENSSPAP00000019123	Proteasome activator subunit 3.	RPN13_C domain-containing protein.	0.774
ENSSPAP00000002991	LOC103356008	ENSSPAP00000002991	ENSSPAP00000000271	Proteasome activator subunit 3.	Adhesion regulating molecule 1.	0.774
ENSSPAP00000002991	p2rx1	ENSSPAP00000002991	ENSSPAP00000017085	Proteasome activator subunit 3.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.459
ENSSPAP00000002991	psmd14	ENSSPAP00000002991	ENSSPAP00000007064	Proteasome activator subunit 3.	Proteasome 26S subunit, non-ATPase 14.	0.945
ENSSPAP00000002991	psme1	ENSSPAP00000002991	ENSSPAP00000028609	Proteasome activator subunit 3.	Proteasome activator subunit 1.	0.935
ENSSPAP00000002991	psme2	ENSSPAP00000002991	ENSSPAP00000007090	Proteasome activator subunit 3.	Proteasome activator subunit 2.	0.918
ENSSPAP00000008247	LOC103354167	ENSSPAP00000008247	ENSSPAP00000019491	CARD domain-containing protein.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.876
ENSSPAP00000008247	LOC103356717	ENSSPAP00000008247	ENSSPAP00000008660	CARD domain-containing protein.	Diablo, IAP-binding mitochondrial protein a.	0.483
ENSSPAP00000008247	LOC103356718	ENSSPAP00000008247	ENSSPAP00000008702	CARD domain-containing protein.	Diablo, IAP-binding mitochondrial protein a.	0.483
ENSSPAP00000008247	LOC103357518	ENSSPAP00000008247	ENSSPAP00000027348	CARD domain-containing protein.	MALT paracaspase 3.	0.684
ENSSPAP00000008247	LOC103357552	ENSSPAP00000008247	ENSSPAP00000028974	CARD domain-containing protein.	Zgc:153993.	0.540
ENSSPAP00000008247	LOC103360880	ENSSPAP00000008247	ENSSPAP00000019898	CARD domain-containing protein.	Uncharacterized protein.	0.930
ENSSPAP00000008247	LOC103365208	ENSSPAP00000008247	ENSSPAP00000020752	CARD domain-containing protein.	MALT paracaspase 2.	0.684
ENSSPAP00000008247	LOC103369458	ENSSPAP00000008247	ENSSPAP00000006903	CARD domain-containing protein.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.674
ENSSPAP00000008247	LOC103369977	ENSSPAP00000008247	ENSSPAP00000001359	CARD domain-containing protein.	Uncharacterized protein.	0.508
ENSSPAP00000008247	LOC103371515	ENSSPAP00000008247	ENSSPAP00000029713	CARD domain-containing protein.	Uncharacterized protein.	0.653
ENSSPAP00000008247	LOC103376010	ENSSPAP00000008247	ENSSPAP00000019506	CARD domain-containing protein.	P53-induced death domain protein 1.	0.653
ENSSPAP00000008247	bax	ENSSPAP00000008247	ENSSPAP00000015004	CARD domain-containing protein.	BCL2 associated X, apoptosis regulator a.	0.544
ENSSPAP00000008247	card9	ENSSPAP00000008247	ENSSPAP00000030416	CARD domain-containing protein.	CARD domain-containing protein.	0.872
ENSSPAP00000008247	casp2	ENSSPAP00000008247	ENSSPAP00000019445	CARD domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.674