(19 nodes) Negative regulation of protein processing network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (397 aa)
	LOC103367721	SERPIN domain-containing protein; Belongs to the serpin family. (420 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	ENSSPAP00000011743	Uncharacterized protein. (154 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (388 aa)
	glg1	Golgi glycoprotein 1b. (1086 aa)
	chac1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (196 aa)
	tmem98	Transmembrane protein 98. (224 aa)
	LOC103363136	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (208 aa)
	ENSSPAP00000029941	Growth arrest-specific 1b. (261 aa)
	ENSSPAP00000027952	Growth arrest-specific 1a. (251 aa)
	ENSSPAP00000027058	Uncharacterized protein. (257 aa)
	ENSSPAP00000024918	Uncharacterized protein. (247 aa)
	LOC103370376	Uncharacterized protein. (430 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2421 aa)
	ENSSPAP00000014599	Uncharacterized protein. (245 aa)
	LOC103355759	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
	LOC103370194	SERPIN domain-containing protein; Belongs to the serpin family. (462 aa)
	bcl2l12	Si:ch73-248e21.1. (359 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000014599	LOC103367721	ENSSPAP00000014599	ENSSPAP00000004702	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.420
ENSSPAP00000014599	LOC103370194	ENSSPAP00000014599	ENSSPAP00000013154	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.420
ENSSPAP00000014599	serpine1	ENSSPAP00000014599	ENSSPAP00000011270	Uncharacterized protein.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.434
ENSSPAP00000014599	serpine2	ENSSPAP00000014599	ENSSPAP00000004751	Uncharacterized protein.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.	0.434
ENSSPAP00000027058	ENSSPAP00000027952	ENSSPAP00000027058	ENSSPAP00000027952	Uncharacterized protein.	Growth arrest-specific 1a.	0.904
ENSSPAP00000027058	ENSSPAP00000029941	ENSSPAP00000027058	ENSSPAP00000029941	Uncharacterized protein.	Growth arrest-specific 1b.	0.903
ENSSPAP00000027952	ENSSPAP00000027058	ENSSPAP00000027952	ENSSPAP00000027058	Growth arrest-specific 1a.	Uncharacterized protein.	0.904
ENSSPAP00000027952	ENSSPAP00000029941	ENSSPAP00000027952	ENSSPAP00000029941	Growth arrest-specific 1a.	Growth arrest-specific 1b.	0.901
ENSSPAP00000029941	ENSSPAP00000027058	ENSSPAP00000029941	ENSSPAP00000027058	Growth arrest-specific 1b.	Uncharacterized protein.	0.903
ENSSPAP00000029941	ENSSPAP00000027952	ENSSPAP00000029941	ENSSPAP00000027952	Growth arrest-specific 1b.	Growth arrest-specific 1a.	0.901
LOC103355759	LOC103367721	ENSSPAP00000014086	ENSSPAP00000004702	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.420
LOC103355759	LOC103370194	ENSSPAP00000014086	ENSSPAP00000013154	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.420
LOC103355759	serpine1	ENSSPAP00000014086	ENSSPAP00000011270	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.434
LOC103355759	serpine2	ENSSPAP00000014086	ENSSPAP00000004751	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.	0.434
LOC103363136	chac1	ENSSPAP00000030967	ENSSPAP00000010178	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.899
LOC103367721	ENSSPAP00000014599	ENSSPAP00000004702	ENSSPAP00000014599	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.420
LOC103367721	LOC103355759	ENSSPAP00000004702	ENSSPAP00000014086	SERPIN domain-containing protein; Belongs to the serpin family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.420
LOC103367721	ctsz	ENSSPAP00000004702	ENSSPAP00000002603	SERPIN domain-containing protein; Belongs to the serpin family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.420
LOC103370194	ENSSPAP00000014599	ENSSPAP00000013154	ENSSPAP00000014599	SERPIN domain-containing protein; Belongs to the serpin family.	Uncharacterized protein.	0.420
LOC103370194	LOC103355759	ENSSPAP00000013154	ENSSPAP00000014086	SERPIN domain-containing protein; Belongs to the serpin family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.420