(59 nodes) Phenol-containing compound metabolic process network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hdc	Histidine decarboxylase. (676 aa)
	ENSSPAP00000007986	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	TYR	Tyrosinase. (547 aa)
	prkn	RBR-type E3 ubiquitin transferase. (341 aa)
	dct	Dopachrome tautomerase. (516 aa)
	ENSSPAP00000005643	Ring finger protein 180. (513 aa)
	tyrp1	Tyrosinase related protein 1. (521 aa)
	LOC103356648	Tyrosine hydroxylase 2. (471 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	LOC103363832	Dual oxidase. (1497 aa)
	rnf180	Ring finger protein 180. (514 aa)
	th	Tyrosine hydroxylase. (486 aa)
	tph2	Tryptophan hydroxylase 2 (tryptophan 5-monooxygenase). (490 aa)
	dbh	Dopamine beta-hydroxylase (dopamine beta-monooxygenase). (569 aa)
	sncaip	Synuclein, alpha interacting protein. (709 aa)
	ENSSPAP00000028424	Thyroglobulin type-1 domain-containing protein. (98 aa)
	ENSSPAP00000028461	COesterase domain-containing protein. (775 aa)
	comt	Catechol-O-methyltransferase b. (265 aa)
	LOC103376235	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (271 aa)
	DIO3	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (268 aa)
	nox5	NADPH oxidase, EF-hand calcium binding domain 5. (729 aa)
	LOC103376271	Type II iodothyronine deiodinase-like. (271 aa)
	LOC103372675	Cbp/p300-interacting transactivator 1-like. (153 aa)
	TPH1	Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a. (480 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	maob	Amine oxidase. (491 aa)
	ENSSPAP00000022667	Uncharacterized protein. (459 aa)
	LOC103356961	Oculocutaneous albinism II. (744 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (153 aa)
	LOC103362426	Endothelin receptor type Ab. (313 aa)
	pmel	Premelanosome protein b. (598 aa)
	CPQ	Carboxypeptidase Q. (488 aa)
	ENSSPAP00000028059	Dopa decarboxylase. (257 aa)
	fah	Fumarylacetoacetase. (418 aa)
	IYD	Iodotyrosine deiodinase. (292 aa)
	LOC103360796	GTP_cyclohydroI domain-containing protein. (246 aa)
	LOC103368817	D-dopachrome tautomerase. (118 aa)
	moxd1	Monooxygenase, DBH-like 1, like. (526 aa)
	tyr	Tyrosinase. (540 aa)
	trpc1	Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (762 aa)
	LOC103372127	Transmembrane O-methyltransferase. (259 aa)
	btbd9	BTB (POZ) domain containing 9. (612 aa)
	ENSSPAP00000025154	Uncharacterized protein. (121 aa)
	LOC103373802	GTP cyclohydrolase 2. (226 aa)
	crym	Crystallin, mu. (315 aa)
	LOC103353170	Tyrosinase-related protein 1b. (533 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (138 aa)
	ENSSPAP00000024086	BH4_2 domain-containing protein. (205 aa)
	PNMT	Phenylethanolamine N-methyltransferase. (355 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (381 aa)
	LOC103362967	Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa)
	dao	D-amino-acid oxidase, tandem duplicate 2. (346 aa)
	ENSSPAP00000014923	Uncharacterized protein. (227 aa)
	LOC103362984	Sulfotransferase; Belongs to the sulfotransferase 1 family. (268 aa)
	ENSSPAP00000014452	Uncharacterized protein. (85 aa)
	gch1	GTP cyclohydrolase 1. (320 aa)
	SLC16A2	Solute carrier family 16 member 2. (564 aa)
	LOC103374795	Amine oxidase. (527 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPQ	ENSSPAP00000028424	ENSSPAP00000017255	ENSSPAP00000028424	Carboxypeptidase Q.	Thyroglobulin type-1 domain-containing protein.	0.555
CPQ	ENSSPAP00000028461	ENSSPAP00000017255	ENSSPAP00000028461	Carboxypeptidase Q.	COesterase domain-containing protein.	0.562
ENSSPAP00000007986	ENSSPAP00000022667	ENSSPAP00000007986	ENSSPAP00000022667	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.600
ENSSPAP00000007986	LOC103353170	ENSSPAP00000007986	ENSSPAP00000024502	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase-related protein 1b.	0.511
ENSSPAP00000007986	LOC103356961	ENSSPAP00000007986	ENSSPAP00000022153	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Oculocutaneous albinism II.	0.631
ENSSPAP00000007986	TYR	ENSSPAP00000007986	ENSSPAP00000007976	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase.	0.668
ENSSPAP00000007986	dct	ENSSPAP00000007986	ENSSPAP00000007547	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Dopachrome tautomerase.	0.551
ENSSPAP00000007986	tyr	ENSSPAP00000007986	ENSSPAP00000027394	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase.	0.657
ENSSPAP00000007986	tyrp1	ENSSPAP00000007986	ENSSPAP00000005241	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	Tyrosinase related protein 1.	0.644
ENSSPAP00000022667	ENSSPAP00000007986	ENSSPAP00000022667	ENSSPAP00000007986	Uncharacterized protein.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	0.600
ENSSPAP00000022667	ENSSPAP00000028059	ENSSPAP00000022667	ENSSPAP00000028059	Uncharacterized protein.	Dopa decarboxylase.	0.822
ENSSPAP00000022667	LOC103353170	ENSSPAP00000022667	ENSSPAP00000024502	Uncharacterized protein.	Tyrosinase-related protein 1b.	0.586
ENSSPAP00000022667	LOC103356648	ENSSPAP00000022667	ENSSPAP00000004703	Uncharacterized protein.	Tyrosine hydroxylase 2.	0.901
ENSSPAP00000022667	LOC103356961	ENSSPAP00000022667	ENSSPAP00000022153	Uncharacterized protein.	Oculocutaneous albinism II.	0.579
ENSSPAP00000022667	TYR	ENSSPAP00000022667	ENSSPAP00000007976	Uncharacterized protein.	Tyrosinase.	0.924
ENSSPAP00000022667	hdc	ENSSPAP00000022667	ENSSPAP00000011214	Uncharacterized protein.	Histidine decarboxylase.	0.822
ENSSPAP00000022667	th	ENSSPAP00000022667	ENSSPAP00000002050	Uncharacterized protein.	Tyrosine hydroxylase.	0.901
ENSSPAP00000022667	tyr	ENSSPAP00000022667	ENSSPAP00000027394	Uncharacterized protein.	Tyrosinase.	0.903
ENSSPAP00000022667	tyrp1	ENSSPAP00000022667	ENSSPAP00000005241	Uncharacterized protein.	Tyrosinase related protein 1.	0.585
ENSSPAP00000024086	prkn	ENSSPAP00000024086	ENSSPAP00000007653	BH4_2 domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.711