(17 nodes) Neuronal action potential network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC103372256	Si:ch211-247n2.1. (233 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2514 aa)
	LOC103359698	Potassium large conductance calcium-activated channel, subfamily M, beta member 2. (216 aa)
	LOC103376591	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1714 aa)
	LOC103363272	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (312 aa)
	LOC103368275	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1862 aa)
	LOC103364869	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (306 aa)
	GJD2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
	p2rx3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (373 aa)
	KCNMB4	Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (250 aa)
	p2rx1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (421 aa)
	LOC103354597	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
	LOC103368290	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1768 aa)
	ENSSPAP00000009303	Purinergic receptor P2X, ligand-gated ion channel, 3b. (345 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (578 aa)
	LOC103371728	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1846 aa)
	LOC103362208	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1889 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000009303	p2rx1	ENSSPAP00000009303	ENSSPAP00000017085	Purinergic receptor P2X, ligand-gated ion channel, 3b.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.895
ENSSPAP00000009303	p2rx7	ENSSPAP00000009303	ENSSPAP00000004918	Purinergic receptor P2X, ligand-gated ion channel, 3b.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.859
GJD2	LOC103363272	ENSSPAP00000021067	ENSSPAP00000001360	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.884
GJD2	LOC103364869	ENSSPAP00000021067	ENSSPAP00000000355	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.934
KCNMB4	LOC103354597	ENSSPAP00000018489	ENSSPAP00000013209	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
KCNMB4	LOC103359698	ENSSPAP00000018489	ENSSPAP00000003293	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Potassium large conductance calcium-activated channel, subfamily M, beta member 2.	0.842
KCNMB4	LOC103362208	ENSSPAP00000018489	ENSSPAP00000003973	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
KCNMB4	LOC103368275	ENSSPAP00000018489	ENSSPAP00000000565	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
KCNMB4	LOC103368290	ENSSPAP00000018489	ENSSPAP00000010392	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
KCNMB4	LOC103371728	ENSSPAP00000018489	ENSSPAP00000004651	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
KCNMB4	LOC103376591	ENSSPAP00000018489	ENSSPAP00000002438	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.501
LOC103354597	KCNMB4	ENSSPAP00000013209	ENSSPAP00000018489	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	0.501
LOC103359698	KCNMB4	ENSSPAP00000003293	ENSSPAP00000018489	Potassium large conductance calcium-activated channel, subfamily M, beta member 2.	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	0.842
LOC103359698	LOC103372256	ENSSPAP00000003293	ENSSPAP00000003832	Potassium large conductance calcium-activated channel, subfamily M, beta member 2.	Si:ch211-247n2.1.	0.831
LOC103362208	KCNMB4	ENSSPAP00000003973	ENSSPAP00000018489	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	0.501
LOC103363272	GJD2	ENSSPAP00000001360	ENSSPAP00000021067	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.884
LOC103363272	LOC103364869	ENSSPAP00000001360	ENSSPAP00000000355	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.884
LOC103364869	GJD2	ENSSPAP00000000355	ENSSPAP00000021067	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.934
LOC103364869	LOC103363272	ENSSPAP00000000355	ENSSPAP00000001360	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.884
LOC103368275	KCNMB4	ENSSPAP00000000565	ENSSPAP00000018489	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium calcium-activated channel subfamily M regulatory beta subunit 4.	0.501