54 items (Stegastes partitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103365693	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (496 aa)
	LOC103368476	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (166 aa)
	LOC103374198	Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
	LOC103371785	Uncharacterized protein. (226 aa)
	LOC103368433	Colony stimulating factor 1b (macrophage). (270 aa)
	ENSSPAP00000005875	Uncharacterized protein. (453 aa)
	ENSSPAP00000005831	Low density lipoprotein receptor-related protein 6. (923 aa)
	LOC103356680	CTCK domain-containing protein. (208 aa)
	ENSSPAP00000005369	Uncharacterized protein. (446 aa)
	fem1b	Fem-1 homolog b (C. elegans). (627 aa)
	ENSSPAP00000004345	Fibrinogen C-terminal domain-containing protein. (290 aa)
	LOC103354448	Peptidase S72 domain-containing protein. (910 aa)
	sostdc1	Sclerostin domain containing 1a. (250 aa)
	LOC103362330	NK3 homeobox 1. (192 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	LOC103375280	Transforming growth factor beta; Belongs to the TGF-beta family. (333 aa)
	LOC103371819	Insulin-like growth factor binding protein 5a. (264 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	LOC103371455	Homeobox protein Nkx-3.1-like. (192 aa)
	cul3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	NKX2-3	NK2 homeobox 3. (312 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
	LOC103365298	Aryl hydrocarbon receptor nuclear translocator. (693 aa)
	ENSSPAP00000025192	EGF-like domain-containing protein. (359 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (382 aa)
	ENSSPAP00000024086	BH4_2 domain-containing protein. (205 aa)
	LOC103374965	Zmp:0000000846. (2380 aa)
	ENSSPAP00000023641	Transforming growth factor, alpha. (218 aa)
	fgl1	Fibrinogen C-terminal domain-containing protein. (318 aa)
	tgfb2	Transforming growth factor, beta 2. (144 aa)
	ENSSPAP00000001228	Uncharacterized protein. (546 aa)
	nav3	Neuron navigator 3. (2448 aa)
	LOC103364251	Insulin-like growth factor binding protein 5a. (267 aa)
	selenoh	Uncharacterized protein. (114 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	LOC103363570	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	ar	Uncharacterized protein. (685 aa)
	cebpb	CCAAT enhancer binding protein beta. (299 aa)
	ENSSPAP00000018210	EGF-like domain-containing protein. (95 aa)
	nkx2-3	NK2 homeobox 3. (356 aa)
	LOC103373135	Peptidase S72 domain-containing protein. (881 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (768 aa)
	arnt2	Aryl-hydrocarbon receptor nuclear translocator 2. (715 aa)
	wnt2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	mki67	Marker of proliferation Ki-67. (1945 aa)
	LOC103371033	Dystroglycan 1. (891 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC103373263	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	hnf1b	HNF1 homeobox Ba. (585 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
	LOC103356464	Tenascin C. (1729 aa)
	LOC103373366	Androgen receptor. (758 aa)
	LOC103375110	Uncharacterized protein. (347 aa)
	ENSSPAP00000001331	Uncharacterized protein. (887 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	cul3	ENSSPAP00000019914	ENSSPAP00000026553	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.898
CUL3	fem1b	ENSSPAP00000019914	ENSSPAP00000005058	Cullin 3; Belongs to the cullin family.	Fem-1 homolog b (C. elegans).	0.531
CUL3	nav3	ENSSPAP00000019914	ENSSPAP00000000869	Cullin 3; Belongs to the cullin family.	Neuron navigator 3.	0.414
ENSSPAP00000001228	LOC103354448	ENSSPAP00000001228	ENSSPAP00000003995	Uncharacterized protein.	Peptidase S72 domain-containing protein.	0.730
ENSSPAP00000001228	LOC103371033	ENSSPAP00000001228	ENSSPAP00000031011	Uncharacterized protein.	Dystroglycan 1.	0.730
ENSSPAP00000001228	LOC103373135	ENSSPAP00000001228	ENSSPAP00000017723	Uncharacterized protein.	Peptidase S72 domain-containing protein.	0.729
ENSSPAP00000001331	LOC103354448	ENSSPAP00000001331	ENSSPAP00000003995	Uncharacterized protein.	Peptidase S72 domain-containing protein.	0.730
ENSSPAP00000001331	LOC103371033	ENSSPAP00000001331	ENSSPAP00000031011	Uncharacterized protein.	Dystroglycan 1.	0.730
ENSSPAP00000001331	LOC103373135	ENSSPAP00000001331	ENSSPAP00000017723	Uncharacterized protein.	Peptidase S72 domain-containing protein.	0.729
ENSSPAP00000005369	ENSSPAP00000023641	ENSSPAP00000005369	ENSSPAP00000023641	Uncharacterized protein.	Transforming growth factor, alpha.	0.508
ENSSPAP00000005369	LOC103368476	ENSSPAP00000005369	ENSSPAP00000009514	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.468
ENSSPAP00000005369	wnt2	ENSSPAP00000005369	ENSSPAP00000011745	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.870
ENSSPAP00000005831	ENSSPAP00000023641	ENSSPAP00000005831	ENSSPAP00000023641	Low density lipoprotein receptor-related protein 6.	Transforming growth factor, alpha.	0.508
ENSSPAP00000005831	LOC103368476	ENSSPAP00000005831	ENSSPAP00000009514	Low density lipoprotein receptor-related protein 6.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.468
ENSSPAP00000005831	wnt2	ENSSPAP00000005831	ENSSPAP00000011745	Low density lipoprotein receptor-related protein 6.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.870
ENSSPAP00000005875	ENSSPAP00000023641	ENSSPAP00000005875	ENSSPAP00000023641	Uncharacterized protein.	Transforming growth factor, alpha.	0.508
ENSSPAP00000005875	LOC103368476	ENSSPAP00000005875	ENSSPAP00000009514	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.468
ENSSPAP00000005875	wnt2	ENSSPAP00000005875	ENSSPAP00000011745	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.870
ENSSPAP00000023641	ENSSPAP00000005369	ENSSPAP00000023641	ENSSPAP00000005369	Transforming growth factor, alpha.	Uncharacterized protein.	0.508
ENSSPAP00000023641	ENSSPAP00000005831	ENSSPAP00000023641	ENSSPAP00000005831	Transforming growth factor, alpha.	Low density lipoprotein receptor-related protein 6.	0.508