(23 nodes) Desmosome network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103359554	Uncharacterized protein. (750 aa)
	PKP1	Plakophilin 1. (722 aa)
	PKP3	Plakophilin 3a. (830 aa)
	pkp2	Plakophilin 2. (788 aa)
	LOC103354309	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1048 aa)
	vcl	Vinculin b. (1066 aa)
	LOC103362533	Junction plakoglobin a. (729 aa)
	klhl24	Kelch-like family member 24a. (600 aa)
	jam3	Junctional adhesion molecule 3a. (333 aa)
	LOC103357892	Junctional adhesion molecule 3b. (302 aa)
	LOC103357339	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (2043 aa)
	ENSSPAP00000015585	CA domain-containing protein. (179 aa)
	LOC103357338	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1314 aa)
	KAZN	Kazrin, periplakin interacting protein a. (725 aa)
	LOC103360703	Si:ch211-256e16.3. (618 aa)
	klhl6	Kelch-like family member 6. (608 aa)
	ENSSPAP00000009102	Kazrin, periplakin interacting protein b. (728 aa)
	LOC103369010	Vinculin a. (1126 aa)
	LOC103371146	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1111 aa)
	LOC103371145	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (851 aa)
	ENSSPAP00000007206	POF1B actin binding protein. (427 aa)
	LOC103355899	Plakophilin 1b. (729 aa)
	pnn	Pinin, desmosome associated protein. (678 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000015585	LOC103355899	ENSSPAP00000015585	ENSSPAP00000002378	CA domain-containing protein.	Plakophilin 1b.	0.684
ENSSPAP00000015585	LOC103359554	ENSSPAP00000015585	ENSSPAP00000013044	CA domain-containing protein.	Uncharacterized protein.	0.689
ENSSPAP00000015585	LOC103362533	ENSSPAP00000015585	ENSSPAP00000024322	CA domain-containing protein.	Junction plakoglobin a.	0.689
ENSSPAP00000015585	LOC103369010	ENSSPAP00000015585	ENSSPAP00000009037	CA domain-containing protein.	Vinculin a.	0.513
ENSSPAP00000015585	LOC103371145	ENSSPAP00000015585	ENSSPAP00000007883	CA domain-containing protein.	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.856
ENSSPAP00000015585	PKP1	ENSSPAP00000015585	ENSSPAP00000031367	CA domain-containing protein.	Plakophilin 1.	0.684
ENSSPAP00000015585	PKP3	ENSSPAP00000015585	ENSSPAP00000030433	CA domain-containing protein.	Plakophilin 3a.	0.748
ENSSPAP00000015585	pkp2	ENSSPAP00000015585	ENSSPAP00000026228	CA domain-containing protein.	Plakophilin 2.	0.743
ENSSPAP00000015585	vcl	ENSSPAP00000015585	ENSSPAP00000025648	CA domain-containing protein.	Vinculin b.	0.513
LOC103354309	LOC103355899	ENSSPAP00000026071	ENSSPAP00000002378	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 1b.	0.684
LOC103354309	LOC103359554	ENSSPAP00000026071	ENSSPAP00000013044	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein.	0.689
LOC103354309	LOC103362533	ENSSPAP00000026071	ENSSPAP00000024322	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Junction plakoglobin a.	0.689
LOC103354309	LOC103369010	ENSSPAP00000026071	ENSSPAP00000009037	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Vinculin a.	0.513
LOC103354309	LOC103371145	ENSSPAP00000026071	ENSSPAP00000007883	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.860
LOC103354309	PKP1	ENSSPAP00000026071	ENSSPAP00000031367	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 1.	0.684
LOC103354309	PKP3	ENSSPAP00000026071	ENSSPAP00000030433	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 3a.	0.748
LOC103354309	pkp2	ENSSPAP00000026071	ENSSPAP00000026228	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 2.	0.743
LOC103354309	vcl	ENSSPAP00000026071	ENSSPAP00000025648	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Vinculin b.	0.513
LOC103355899	ENSSPAP00000015585	ENSSPAP00000002378	ENSSPAP00000015585	Plakophilin 1b.	CA domain-containing protein.	0.684
LOC103355899	LOC103354309	ENSSPAP00000002378	ENSSPAP00000026071	Plakophilin 1b.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.684