(41 nodes) Embryonic limb morphogenesis network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103374781	T-box transcription factor 3b. (569 aa)
	ENSSPAP00000006435	Uncharacterized protein. (139 aa)
	ENSSPAP00000006426	Homeobox domain-containing protein. (164 aa)
	LOC103361651	Mothers against decapentaplegic homolog. (503 aa)
	LOC103358884	Mothers against decapentaplegic homolog. (651 aa)
	LOC103356681	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	frem3	Fras1 related extracellular matrix 3. (3142 aa)
	SMAD4	Mothers against decapentaplegic homolog. (528 aa)
	sall4	Spalt-like transcription factor 4. (1081 aa)
	ift140	Intraflagellar transport 140 homolog (Chlamydomonas). (1420 aa)
	LOC103361279	Lymphoid enhancer-binding factor 1. (364 aa)
	LOC103374507	Mothers against decapentaplegic homolog. (472 aa)
	sp9	Sp9 transcription factor. (439 aa)
	WDPCP	WD repeat containing planar cell polarity effector. (634 aa)
	ENSSPAP00000007333	Uncharacterized protein. (69 aa)
	LOC103355596	Homeobox protein engrailed-like. (293 aa)
	tbx4	T-box transcription factor 4. (568 aa)
	LOC103355069	Sterile alpha motif and leucine zipper containing kinase AZK. (298 aa)
	LOC103372265	Protein kinase domain-containing protein. (578 aa)
	LOC103363427	FRAS1 related extracellular matrix 2b. (3114 aa)
	tbx3	T-box transcription factor 3a. (715 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	fbxw4	F-box and WD repeat domain containing 4. (390 aa)
	LOC103372019	Fraser extracellular matrix complex subunit 1. (3109 aa)
	msx1	Muscle segment homeobox 1a. (283 aa)
	LOC103366952	Sp8 transcription factor b. (452 aa)
	tbx5	Uncharacterized protein. (529 aa)
	GREM1	Gremlin; Belongs to the DAN family. (172 aa)
	LOC103371952	Uncharacterized protein. (341 aa)
	wdr19	WD repeat domain 19. (1341 aa)
	ENSSPAP00000027952	Growth arrest-specific 1a. (251 aa)
	ENSSPAP00000028083	Uncharacterized protein. (221 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	ift52	Intraflagellar transport 52 homolog (Chlamydomonas). (439 aa)
	rpgrip1l	RPGRIP1 like. (1249 aa)
	hoxc10	Homeobox C10a. (379 aa)
	mks1	MKS transition zone complex subunit 1. (563 aa)
	LOC103360321	Homeobox protein engrailed-like. (283 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000006426	ENSSPAP00000006435	ENSSPAP00000006426	ENSSPAP00000006435	Homeobox domain-containing protein.	Uncharacterized protein.	0.815
ENSSPAP00000006426	LOC103355596	ENSSPAP00000006426	ENSSPAP00000007436	Homeobox domain-containing protein.	Homeobox protein engrailed-like.	0.531
ENSSPAP00000006426	LOC103360321	ENSSPAP00000006426	ENSSPAP00000031009	Homeobox domain-containing protein.	Homeobox protein engrailed-like.	0.531
ENSSPAP00000006435	ENSSPAP00000006426	ENSSPAP00000006435	ENSSPAP00000006426	Uncharacterized protein.	Homeobox domain-containing protein.	0.815
ENSSPAP00000006435	LOC103355596	ENSSPAP00000006435	ENSSPAP00000007436	Uncharacterized protein.	Homeobox protein engrailed-like.	0.531
ENSSPAP00000006435	LOC103360321	ENSSPAP00000006435	ENSSPAP00000031009	Uncharacterized protein.	Homeobox protein engrailed-like.	0.531
ENSSPAP00000028083	bax	ENSSPAP00000028083	ENSSPAP00000015004	Uncharacterized protein.	BCL2 associated X, apoptosis regulator a.	0.993
LOC103355069	LOC103358884	ENSSPAP00000009055	ENSSPAP00000005222	Sterile alpha motif and leucine zipper containing kinase AZK.	Mothers against decapentaplegic homolog.	0.456
LOC103355069	LOC103361651	ENSSPAP00000009055	ENSSPAP00000005949	Sterile alpha motif and leucine zipper containing kinase AZK.	Mothers against decapentaplegic homolog.	0.456
LOC103355069	LOC103372265	ENSSPAP00000009055	ENSSPAP00000009546	Sterile alpha motif and leucine zipper containing kinase AZK.	Protein kinase domain-containing protein.	0.899
LOC103355069	LOC103374507	ENSSPAP00000009055	ENSSPAP00000001838	Sterile alpha motif and leucine zipper containing kinase AZK.	Mothers against decapentaplegic homolog.	0.456
LOC103355069	SMAD4	ENSSPAP00000009055	ENSSPAP00000003348	Sterile alpha motif and leucine zipper containing kinase AZK.	Mothers against decapentaplegic homolog.	0.456
LOC103355069	med1	ENSSPAP00000009055	ENSSPAP00000028174	Sterile alpha motif and leucine zipper containing kinase AZK.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.410
LOC103355596	ENSSPAP00000006426	ENSSPAP00000007436	ENSSPAP00000006426	Homeobox protein engrailed-like.	Homeobox domain-containing protein.	0.531
LOC103355596	ENSSPAP00000006435	ENSSPAP00000007436	ENSSPAP00000006435	Homeobox protein engrailed-like.	Uncharacterized protein.	0.531
LOC103358884	LOC103355069	ENSSPAP00000005222	ENSSPAP00000009055	Mothers against decapentaplegic homolog.	Sterile alpha motif and leucine zipper containing kinase AZK.	0.456
LOC103358884	LOC103361279	ENSSPAP00000005222	ENSSPAP00000002070	Mothers against decapentaplegic homolog.	Lymphoid enhancer-binding factor 1.	0.954
LOC103358884	LOC103361651	ENSSPAP00000005222	ENSSPAP00000005949	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.818
LOC103358884	LOC103372265	ENSSPAP00000005222	ENSSPAP00000009546	Mothers against decapentaplegic homolog.	Protein kinase domain-containing protein.	0.456
LOC103358884	SMAD4	ENSSPAP00000005222	ENSSPAP00000003348	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.819