(148 nodes) Negative regulation of cell migration network (Stegastes partitus)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	podn	Podocan. (593 aa)
	ENSSPAP00000019344	GTP binding protein 4. (383 aa)
	ripor2	RHO family interacting cell polarization regulator 2. (1076 aa)
	ENSSPAP00000000108	Claudin 5b. (107 aa)
	LOC103353922	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (477 aa)
	ENSSPAP00000000647	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	tnn	Tenascin N. (1121 aa)
	LOC103372191	Uncharacterized protein. (1298 aa)
	LOC103357131	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	rabgef1	Uncharacterized protein. (512 aa)
	ADORA3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (328 aa)
	tbxa2r	Thromboxane A2 receptor. (373 aa)
	adipor1	Adiponectin receptor 1a. (376 aa)
	LOC103354432	Abhydrolase domain containing 6b. (339 aa)
	LOC103368337	G_PROTEIN_RECEP_F1_2 domain-containing protein. (270 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (292 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (135 aa)
	afdn	Afadin, adherens junction formation factor a. (1596 aa)
	LOC103358838	Zinc finger, MYND-type containing 8. (1012 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	LOC103371712	SLIT-ROBO Rho GTPase activating protein 1a. (1106 aa)
	LOC103352803	Uncharacterized protein. (377 aa)
	LOC103354448	Peptidase S72 domain-containing protein. (910 aa)
	myocd	SAP domain-containing protein. (788 aa)
	LOC103372831	Elastin microfibril interfacer 1b. (1212 aa)
	mcc	Usher syndrome 1C binding protein 1. (701 aa)
	LOC103359992	BMERB domain-containing protein. (187 aa)
	LOC103356110	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (537 aa)
	bmp10	Bone morphogenetic protein 10. (468 aa)
	LOC103361652	Bone morphogenetic protein 10, like. (459 aa)
	LOC103365535	Uncharacterized protein. (1748 aa)
	vash2	Vasohibin 2. (289 aa)
	LOC103363373	Si:dkey-175m17.7. (872 aa)
	nf1	Neurofibromin 1b. (2780 aa)
	mecp2	Methyl CpG binding protein 2. (974 aa)
	LOC103358915	Si:ch211-191a24.4. (289 aa)
	LOC103367270	VPS9 domain-containing protein. (1015 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1457 aa)
	CCN3	Cellular communication network factor 3. (378 aa)
	ENSSPAP00000007705	Uncharacterized protein. (491 aa)
	llgl2	LLGL scribble cell polarity complex component 2. (1004 aa)
	LOC103368126	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (379 aa)
	RAP2A	RAP2A, member of RAS oncogene family. (183 aa)
	LOC103371151	Insulin like growth factor binding protein 3. (295 aa)
	arid2	AT rich interactive domain 2 (ARID, RFX-like). (1688 aa)
	rap2c	RAP2C, member of RAS oncogene family. (183 aa)
	LOC103364465	Zgc:194281. (213 aa)
	miip	Uncharacterized protein. (266 aa)
	LOC103371819	Insulin-like growth factor binding protein 5a. (264 aa)
	gpr18	G protein-coupled receptor 18. (353 aa)
	LOC103372290	Uncharacterized protein. (259 aa)
	scai	Suppressor of cancer cell invasion. (565 aa)
	GTPBP4	OBG-type G domain-containing protein. (209 aa)
	ENSSPAP00000010975	F-BAR domain-containing protein. (204 aa)
	ENSSPAP00000010999	F-BAR domain-containing protein. (299 aa)
	nisch	PX domain-containing protein. (521 aa)
	LOC103371850	Prostaglandin E receptor 4 (subtype EP4) b. (477 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (388 aa)
	LOC103360700	Guanine nucleotide binding protein (G protein), alpha 13b. (414 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2028 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (613 aa)
	LOC103375252	Uncharacterized protein. (859 aa)
	VASH1	Vasohibin 1. (335 aa)
	LOC103357827	RAB guanine nucleotide exchange factor (GEF) 1, like. (507 aa)
	LOC103369070	Protein tyrosine phosphatase receptor type Z1b. (1284 aa)
	ptpn23	Protein tyrosine phosphatase, non-receptor type 23, a. (1960 aa)
	LOC103361204	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
	LOC103361214	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (193 aa)
	LOC103360740	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	LOC103359554	Uncharacterized protein. (750 aa)
	LOC103363473	Regulator of cell cycle. (126 aa)
	LOC103372345	Elastin microfibril interfacer 1a. (1037 aa)
	LOC103370743	Family with sequence similarity 102 member Aa. (369 aa)
	LOC103370742	C-X-C motif chemokine. (110 aa)
	ENSSPAP00000013938	Matrix metallopeptidase 28. (219 aa)
	ENSSPAP00000013955	Uncharacterized protein. (168 aa)
	limch1	LIM and calponin homology domains 1b. (1372 aa)
	LOC103363483	Mothers against decapentaplegic homolog. (476 aa)
	srgap1	SLIT-ROBO Rho GTPase activating protein 1b. (995 aa)
	LOC103366815	Family with sequence similarity 102 member Bb. (378 aa)
	LOC103367871	Interleukin 19 like. (170 aa)
	LOC103362328	Stanniocalcin 1. (278 aa)
	srgap2	SLIT-ROBO Rho GTPase activating protein 2. (746 aa)
	fam102a	Family with sequence similarity 102 member Ab. (399 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	dcn	Decorin; May affect the rate of fibrils formation. (362 aa)
	LOC103366385	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (183 aa)
	LOC103357348	Protein kinase C binding protein 1, like. (1158 aa)
	LOC103353029	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (194 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1262 aa)
	meox2	Mesenchyme homeobox 2a. (315 aa)
	ENSSPAP00000016905	Neurite extension and migration factor b. (1290 aa)
	ENSSPAP00000017677	Nerve growth factor receptor a (TNFR superfamily, member 16). (289 aa)
	LOC103373135	Peptidase S72 domain-containing protein. (881 aa)
	gna12	G protein subunit alpha 12. (385 aa)
	ENSSPAP00000018210	EGF-like domain-containing protein. (95 aa)
	ptprk	Protein tyrosine phosphatase receptor type K. (1443 aa)
	LOC103373648	PIPK domain-containing protein. (383 aa)
	ENSSPAP00000019170	Apolipoprotein Ea. (259 aa)
	pip5kl1	Phosphatidylinositol-4-phosphate 5-kinase-like 1. (468 aa)
	LOC103371033	Dystroglycan 1. (891 aa)
	LOC103357623	Family with sequence similarity 102 member Ba. (370 aa)
	adipor2	Adiponectin receptor 2. (377 aa)
	LOC103368235	Uncharacterized protein. (352 aa)
	LOC103368234	Uncharacterized protein. (364 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC103373263	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	mmrn2	EMI domain-containing protein. (1066 aa)
	ptprt	Protein tyrosine phosphatase receptor type T. (1420 aa)
	c5	Uncharacterized protein. (1563 aa)
	LOC103359796	Uncharacterized protein. (160 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	ENSSPAP00000028945	BMERB domain-containing protein. (158 aa)
	churc1	Churchill domain containing 1. (112 aa)
	SINHCAF	SIN3-HDAC complex associated factor. (311 aa)
	ENSSPAP00000027748	MBD domain-containing protein. (314 aa)
	LOC103364251	Insulin-like growth factor binding protein 5a. (267 aa)
	LOC103370878	SIN3-HDAC complex associated factor, like. (225 aa)
	ptger4	Prostaglandin E receptor 4. (477 aa)
	LOC103371952	Uncharacterized protein. (341 aa)
	inppl1	Inositol polyphosphate phosphatase-like 1a. (1262 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (339 aa)
	ENSSPAP00000026515	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (523 aa)
	card10	Uncharacterized protein. (1030 aa)
	LOC103357016	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (523 aa)
	GREM1	Gremlin; Belongs to the DAN family. (172 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
	LOC103360254	Uncharacterized protein. (1112 aa)
	ENSSPAP00000025535	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (185 aa)
	ENSSPAP00000025192	EGF-like domain-containing protein. (359 aa)
	ptprg	Carbonic anhydrase XVI b. (1404 aa)
	LOC103373808	PDZ domain-containing protein. (143 aa)
	abhd6	Abhydrolase domain containing 6. (337 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (167 aa)
	ENSSPAP00000024385	Tumor necrosis factor, alpha-induced protein 6. (229 aa)
	LOC103362533	Junction plakoglobin a. (729 aa)
	ENSSPAP00000024086	BH4_2 domain-containing protein. (205 aa)
	ENSSPAP00000023760	Uncharacterized protein. (205 aa)
	cldn19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	BMERB1	BMERB domain containing 1. (199 aa)
	ENSSPAP00000022040	Chemokine (C-C motif) ligand 25b. (99 aa)
	dusp10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	flcn	Folliculin. (559 aa)
	LOC103370362	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (248 aa)
	WDR63	WD repeat domain 63. (798 aa)
	LOC103375505	SLIT-ROBO Rho GTPase activating protein 3. (1031 aa)
	cldn5	Claudin 5. (215 aa)
	ENSSPAP00000020574	Uncharacterized protein. (176 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADORA1	LOC103352803	ENSSPAP00000026715	ENSSPAP00000003915	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.630
ADORA1	LOC103360700	ENSSPAP00000026715	ENSSPAP00000011311	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.630
ADORA1	gna12	ENSSPAP00000026715	ENSSPAP00000017907	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 12.	0.630
ADORA3	LOC103352803	ENSSPAP00000002612	ENSSPAP00000003915	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.630
ADORA3	LOC103360700	ENSSPAP00000002612	ENSSPAP00000011311	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.630
ADORA3	gna12	ENSSPAP00000002612	ENSSPAP00000017907	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein subunit alpha 12.	0.630
ENSSPAP00000000108	LOC103357131	ENSSPAP00000000108	ENSSPAP00000001121	Claudin 5b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.503
ENSSPAP00000000108	LOC103361204	ENSSPAP00000000108	ENSSPAP00000012546	Claudin 5b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.638
ENSSPAP00000000108	LOC103361214	ENSSPAP00000000108	ENSSPAP00000012577	Claudin 5b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.638
ENSSPAP00000000108	cldn19	ENSSPAP00000000108	ENSSPAP00000023402	Claudin 5b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.766
ENSSPAP00000000108	cldn5	ENSSPAP00000000108	ENSSPAP00000020839	Claudin 5b.	Claudin 5.	0.503
ENSSPAP00000000108	mmrn2	ENSSPAP00000000108	ENSSPAP00000030224	Claudin 5b.	EMI domain-containing protein.	0.407
ENSSPAP00000000647	LOC103352803	ENSSPAP00000000647	ENSSPAP00000003915	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.841
ENSSPAP00000000647	LOC103360700	ENSSPAP00000000647	ENSSPAP00000011311	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.841
ENSSPAP00000000647	gna12	ENSSPAP00000000647	ENSSPAP00000017907	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 12.	0.841
ENSSPAP00000010975	ENSSPAP00000010999	ENSSPAP00000010975	ENSSPAP00000010999	F-BAR domain-containing protein.	F-BAR domain-containing protein.	0.910
ENSSPAP00000010975	LOC103375505	ENSSPAP00000010975	ENSSPAP00000020978	F-BAR domain-containing protein.	SLIT-ROBO Rho GTPase activating protein 3.	0.863
ENSSPAP00000010975	RAP2A	ENSSPAP00000010975	ENSSPAP00000008466	F-BAR domain-containing protein.	RAP2A, member of RAS oncogene family.	0.400
ENSSPAP00000010975	RAP2B	ENSSPAP00000010975	ENSSPAP00000003594	F-BAR domain-containing protein.	RAP2B, member of RAS oncogene family.	0.400
ENSSPAP00000010975	rap2c	ENSSPAP00000010975	ENSSPAP00000009067	F-BAR domain-containing protein.	RAP2C, member of RAS oncogene family.	0.400