(8 nodes) HOPS complex network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stx17	Syntaxin 17; Belongs to the syntaxin family. (296 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	vps39	VPS39 subunit of HOPS complex. (875 aa)
	ENSSPAP00000007329	Vacuolar protein sorting 16 homolog. (689 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (835 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
	LOC103364969	Hook microtubule-tethering protein 2. (709 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000007329	stx17	ENSSPAP00000007329	ENSSPAP00000031443	Vacuolar protein sorting 16 homolog.	Syntaxin 17; Belongs to the syntaxin family.	0.932
ENSSPAP00000007329	vps11	ENSSPAP00000007329	ENSSPAP00000001644	Vacuolar protein sorting 16 homolog.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.999
ENSSPAP00000007329	vps18	ENSSPAP00000007329	ENSSPAP00000010317	Vacuolar protein sorting 16 homolog.	VPS18 core subunit of CORVET and HOPS complexes.	0.999
ENSSPAP00000007329	vps33a	ENSSPAP00000007329	ENSSPAP00000003072	Vacuolar protein sorting 16 homolog.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.999
ENSSPAP00000007329	vps39	ENSSPAP00000007329	ENSSPAP00000003049	Vacuolar protein sorting 16 homolog.	VPS39 subunit of HOPS complex.	0.999
ENSSPAP00000007329	vps41	ENSSPAP00000007329	ENSSPAP00000005410	Vacuolar protein sorting 16 homolog.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.999
stx17	ENSSPAP00000007329	ENSSPAP00000031443	ENSSPAP00000007329	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting 16 homolog.	0.932
stx17	vps11	ENSSPAP00000031443	ENSSPAP00000001644	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.891
stx17	vps18	ENSSPAP00000031443	ENSSPAP00000010317	Syntaxin 17; Belongs to the syntaxin family.	VPS18 core subunit of CORVET and HOPS complexes.	0.907
stx17	vps33a	ENSSPAP00000031443	ENSSPAP00000003072	Syntaxin 17; Belongs to the syntaxin family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.857
stx17	vps39	ENSSPAP00000031443	ENSSPAP00000003049	Syntaxin 17; Belongs to the syntaxin family.	VPS39 subunit of HOPS complex.	0.976
stx17	vps41	ENSSPAP00000031443	ENSSPAP00000005410	Syntaxin 17; Belongs to the syntaxin family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.965
vps11	ENSSPAP00000007329	ENSSPAP00000001644	ENSSPAP00000007329	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting 16 homolog.	0.999
vps11	stx17	ENSSPAP00000001644	ENSSPAP00000031443	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Syntaxin 17; Belongs to the syntaxin family.	0.891
vps11	vps18	ENSSPAP00000001644	ENSSPAP00000010317	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS18 core subunit of CORVET and HOPS complexes.	0.999
vps11	vps33a	ENSSPAP00000001644	ENSSPAP00000003072	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.	0.996
vps11	vps39	ENSSPAP00000001644	ENSSPAP00000003049	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS39 subunit of HOPS complex.	0.999
vps11	vps41	ENSSPAP00000001644	ENSSPAP00000005410	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.999
vps18	ENSSPAP00000007329	ENSSPAP00000010317	ENSSPAP00000007329	VPS18 core subunit of CORVET and HOPS complexes.	Vacuolar protein sorting 16 homolog.	0.999
vps18	stx17	ENSSPAP00000010317	ENSSPAP00000031443	VPS18 core subunit of CORVET and HOPS complexes.	Syntaxin 17; Belongs to the syntaxin family.	0.907