(32 nodes) Positive regulation of insulin secretion network (Stegastes partitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	psmd9	Proteasome 26S subunit, non-ATPase 9. (213 aa)
	rfx6	Regulatory factor X, 6. (855 aa)
	LOC103371683	Si:dkey-211g8.9. (269 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (333 aa)
	LOC103366615	Motilin_assoc domain-containing protein. (106 aa)
	ENSSPAP00000001250	Guanylate cyclase domain-containing protein. (118 aa)
	ENSSPAP00000011040	Nuclear receptor subfamily 1, group H, member 5. (378 aa)
	tm7sf3	Transmembrane 7 superfamily member 3. (556 aa)
	sri	Uncharacterized protein. (185 aa)
	mpc2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (126 aa)
	adcy8	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (913 aa)
	sirt6	Sirtuin 6. (349 aa)
	capn10	Calpain 10; Belongs to the peptidase C2 family. (666 aa)
	ENSSPAP00000029940	annotation not available (118 aa)
	mcu	Mitochondrial calcium uniporter. (303 aa)
	LOC103360989	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1155 aa)
	LOC103365257	MCU domain-containing protein. (315 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (767 aa)
	c2cd2l	C2cd2 like. (692 aa)
	ENSSPAP00000021317	RabBD domain-containing protein. (130 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (257 aa)
	ENSSPAP00000018582	Rab_eff_C domain-containing protein. (966 aa)
	ENSSPAP00000018576	RabBD domain-containing protein. (111 aa)
	nr0b2	Nuclear receptor subfamily 0, group B, member 2a. (255 aa)
	aacs	Acetoacetyl-CoA synthetase. (676 aa)
	trh	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (270 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	LOC103358468	Mitochondrial calcium uniporter. (377 aa)
	LOC103354601	Grancalcin. (249 aa)
	ENSSPAP00000012421	Nas2_N domain-containing protein. (86 aa)
	ENSSPAP00000012050	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (323 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000001250	ENSSPAP00000012050	ENSSPAP00000001250	ENSSPAP00000012050	Guanylate cyclase domain-containing protein.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.947
ENSSPAP00000001250	adcy8	ENSSPAP00000001250	ENSSPAP00000005445	Guanylate cyclase domain-containing protein.	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.943
ENSSPAP00000011040	nr0b2	ENSSPAP00000011040	ENSSPAP00000017340	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 0, group B, member 2a.	0.727
ENSSPAP00000012050	ENSSPAP00000001250	ENSSPAP00000012050	ENSSPAP00000001250	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase domain-containing protein.	0.947
ENSSPAP00000012050	ENSSPAP00000029940	ENSSPAP00000012050	ENSSPAP00000029940	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	annotation not available	0.947
ENSSPAP00000018576	ENSSPAP00000018582	ENSSPAP00000018576	ENSSPAP00000018582	RabBD domain-containing protein.	Rab_eff_C domain-containing protein.	0.893
ENSSPAP00000018582	ENSSPAP00000018576	ENSSPAP00000018582	ENSSPAP00000018576	Rab_eff_C domain-containing protein.	RabBD domain-containing protein.	0.893
ENSSPAP00000018582	ENSSPAP00000021317	ENSSPAP00000018582	ENSSPAP00000021317	Rab_eff_C domain-containing protein.	RabBD domain-containing protein.	0.877
ENSSPAP00000021317	ENSSPAP00000018582	ENSSPAP00000021317	ENSSPAP00000018582	RabBD domain-containing protein.	Rab_eff_C domain-containing protein.	0.877
ENSSPAP00000029940	ENSSPAP00000012050	ENSSPAP00000029940	ENSSPAP00000012050	annotation not available	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.947
ENSSPAP00000029940	adcy8	ENSSPAP00000029940	ENSSPAP00000005445	annotation not available	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.943
LOC103354601	capn10	ENSSPAP00000013307	ENSSPAP00000031006	Grancalcin.	Calpain 10; Belongs to the peptidase C2 family.	0.588
LOC103366615	trh	ENSSPAP00000001389	ENSSPAP00000015644	Motilin_assoc domain-containing protein.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.778
aacs	sirt6	ENSSPAP00000016763	ENSSPAP00000004471	Acetoacetyl-CoA synthetase.	Sirtuin 6.	0.537
adcy8	ENSSPAP00000001250	ENSSPAP00000005445	ENSSPAP00000001250	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanylate cyclase domain-containing protein.	0.943
adcy8	ENSSPAP00000029940	ENSSPAP00000005445	ENSSPAP00000029940	Adenylate cyclase 8 (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	annotation not available	0.943
capn10	LOC103354601	ENSSPAP00000031006	ENSSPAP00000013307	Calpain 10; Belongs to the peptidase C2 family.	Grancalcin.	0.588
capn10	sri	ENSSPAP00000031006	ENSSPAP00000008487	Calpain 10; Belongs to the peptidase C2 family.	Uncharacterized protein.	0.588
nr0b2	ENSSPAP00000011040	ENSSPAP00000017340	ENSSPAP00000011040	Nuclear receptor subfamily 0, group B, member 2a.	Nuclear receptor subfamily 1, group H, member 5.	0.727
nr0b2	nr1h4	ENSSPAP00000017340	ENSSPAP00000013809	Nuclear receptor subfamily 0, group B, member 2a.	Nuclear receptor subfamily 1, group H, member 4.	0.727