(30 nodes) Sarcoplasmic reticulum membrane network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103365013	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1036 aa)
	LOC103368261	Ryanodine receptor 1a (skeletal). (4896 aa)
	ENSSPAP00000026177	Uncharacterized protein. (913 aa)
	srl	Sarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (508 aa)
	ENSSPAP00000025091	Uncharacterized protein. (83 aa)
	ENSSPAP00000024801	Uncharacterized protein. (1008 aa)
	LOC103368738	Ryanodine receptor 1b (skeletal). (3789 aa)
	tmem109	Uncharacterized protein. (286 aa)
	ryr3	Ryanodine receptor 3. (4831 aa)
	LOC103354614	Peptidylprolyl isomerase. (139 aa)
	ryr2	Ryanodine receptor 2b (cardiac). (4778 aa)
	LOC103372010	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (442 aa)
	atp2a3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (990 aa)
	LOC103362349	Protein kinase domain-containing protein. (563 aa)
	atp2a1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (998 aa)
	cherp	Calcium homeostasis endoplasmic reticulum protein. (923 aa)
	ENSSPAP00000013840	Asp-B-Hydro_N domain-containing protein. (353 aa)
	pln	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (53 aa)
	fkbp1a	Peptidylprolyl isomerase. (108 aa)
	LOC103354588	BTB domain-containing protein. (606 aa)
	fkbp1b	Peptidylprolyl isomerase. (108 aa)
	LOC103371843	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (995 aa)
	atp2a2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1035 aa)
	reep5	Receptor expression-enhancing protein. (189 aa)
	ENSSPAP00000008856	Uncharacterized protein. (44 aa)
	klhl41	Kelch-like family member 41a. (598 aa)
	LOC103358909	PID domain-containing protein. (745 aa)
	ENSSPAP00000004815	Uncharacterized protein. (1032 aa)
	tmem38a	Transmembrane protein 38A. (291 aa)
	LOC103374527	Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (544 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004815	ENSSPAP00000024801	ENSSPAP00000004815	ENSSPAP00000024801	Uncharacterized protein.	Uncharacterized protein.	0.464
ENSSPAP00000004815	ENSSPAP00000026177	ENSSPAP00000004815	ENSSPAP00000026177	Uncharacterized protein.	Uncharacterized protein.	0.464
ENSSPAP00000004815	LOC103368261	ENSSPAP00000004815	ENSSPAP00000030873	Uncharacterized protein.	Ryanodine receptor 1a (skeletal).	0.464
ENSSPAP00000004815	LOC103368738	ENSSPAP00000004815	ENSSPAP00000024677	Uncharacterized protein.	Ryanodine receptor 1b (skeletal).	0.464
ENSSPAP00000004815	ryr2	ENSSPAP00000004815	ENSSPAP00000019473	Uncharacterized protein.	Ryanodine receptor 2b (cardiac).	0.464
ENSSPAP00000004815	ryr3	ENSSPAP00000004815	ENSSPAP00000020928	Uncharacterized protein.	Ryanodine receptor 3.	0.464
ENSSPAP00000008856	ENSSPAP00000024801	ENSSPAP00000008856	ENSSPAP00000024801	Uncharacterized protein.	Uncharacterized protein.	0.755
ENSSPAP00000008856	ENSSPAP00000026177	ENSSPAP00000008856	ENSSPAP00000026177	Uncharacterized protein.	Uncharacterized protein.	0.755
ENSSPAP00000008856	LOC103368261	ENSSPAP00000008856	ENSSPAP00000030873	Uncharacterized protein.	Ryanodine receptor 1a (skeletal).	0.755
ENSSPAP00000008856	LOC103368738	ENSSPAP00000008856	ENSSPAP00000024677	Uncharacterized protein.	Ryanodine receptor 1b (skeletal).	0.755
ENSSPAP00000008856	ryr2	ENSSPAP00000008856	ENSSPAP00000019473	Uncharacterized protein.	Ryanodine receptor 2b (cardiac).	0.755
ENSSPAP00000008856	ryr3	ENSSPAP00000008856	ENSSPAP00000020928	Uncharacterized protein.	Ryanodine receptor 3.	0.755
ENSSPAP00000013840	ENSSPAP00000024801	ENSSPAP00000013840	ENSSPAP00000024801	Asp-B-Hydro_N domain-containing protein.	Uncharacterized protein.	0.690
ENSSPAP00000013840	ENSSPAP00000026177	ENSSPAP00000013840	ENSSPAP00000026177	Asp-B-Hydro_N domain-containing protein.	Uncharacterized protein.	0.721
ENSSPAP00000013840	LOC103368261	ENSSPAP00000013840	ENSSPAP00000030873	Asp-B-Hydro_N domain-containing protein.	Ryanodine receptor 1a (skeletal).	0.856
ENSSPAP00000013840	LOC103368738	ENSSPAP00000013840	ENSSPAP00000024677	Asp-B-Hydro_N domain-containing protein.	Ryanodine receptor 1b (skeletal).	0.856
ENSSPAP00000013840	ryr2	ENSSPAP00000013840	ENSSPAP00000019473	Asp-B-Hydro_N domain-containing protein.	Ryanodine receptor 2b (cardiac).	0.721
ENSSPAP00000013840	ryr3	ENSSPAP00000013840	ENSSPAP00000020928	Asp-B-Hydro_N domain-containing protein.	Ryanodine receptor 3.	0.856
ENSSPAP00000024801	ENSSPAP00000004815	ENSSPAP00000024801	ENSSPAP00000004815	Uncharacterized protein.	Uncharacterized protein.	0.464
ENSSPAP00000024801	ENSSPAP00000008856	ENSSPAP00000024801	ENSSPAP00000008856	Uncharacterized protein.	Uncharacterized protein.	0.755