(51 nodes) Protein localization to chromosome network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wapl	WAPL cohesin release factor a. (1173 aa)
	LOC103376442	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (370 aa)
	bub3	BUB3 mitotic checkpoint protein. (326 aa)
	LOC103369208	Poly [ADP-ribose] polymerase. (1262 aa)
	LOC103368661	Uncharacterized protein. (507 aa)
	LOC103367279	Aurora kinase B; Belongs to the protein kinase superfamily. (332 aa)
	mtbp	MDM2 binding protein. (878 aa)
	LOC103354451	Transcription activation suppressor b. (1851 aa)
	ENSSPAP00000004083	Telo_bind domain-containing protein. (212 aa)
	znf827	Zinc finger protein 827. (1193 aa)
	LOC103363335	H2A histone family, member Y; Belongs to the histone H2A family. (363 aa)
	rb1	Retinoblastoma 1. (909 aa)
	ENSSPAP00000006493	Uncharacterized protein. (104 aa)
	LOC103361657	Nipped-B protein. (2568 aa)
	ENSSPAP00000006942	ANK_REP_REGION domain-containing protein. (352 aa)
	parp3	Poly [ADP-ribose] polymerase. (529 aa)
	LOC103361134	WAPL cohesin release factor b. (1241 aa)
	iffo2	Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (487 aa)
	LOC103358411	TERF1 (TRF1)-interacting nuclear factor 2. (492 aa)
	LOC103362938	Nipped-B protein. (2290 aa)
	LOC103366314	Uncharacterized protein. (1845 aa)
	LOC103365053	Poly [ADP-ribose] polymerase. (1086 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
	lrwd1	Leucine-rich repeats and WD repeat domain containing 1. (736 aa)
	LOC103362961	Uncharacterized protein. (280 aa)
	haspin	Si:dkeyp-26a9.2. (1330 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (597 aa)
	atrx	ATRX chromatin remodeler. (2096 aa)
	mis12	MIS12 kinetochore complex component. (231 aa)
	ENSSPAP00000017877	Uncharacterized protein. (1285 aa)
	LOC103355837	Uncharacterized protein. (1416 aa)
	LOC103357689	Poly [ADP-ribose] polymerase. (1052 aa)
	LOC103356841	Intermediate filament family orphan 1a; Belongs to the intermediate filament family. (641 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2496 aa)
	kntc1	Kinetochore associated 1. (2029 aa)
	LOC103357611	MAU2 sister chromatid cohesion factor. (598 aa)
	spdl1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (568 aa)
	zw10	Zw10 kinetochore protein. (767 aa)
	ENSSPAP00000028301	Telo_bind domain-containing protein. (326 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (411 aa)
	SPO11	Meiotic recombination protein SPO11-like. (381 aa)
	ttk	Ttk protein kinase. (998 aa)
	LOC103369363	X-ray repair complementing defective repair in Chinese hamster cells 4. (336 aa)
	LOC103370838	SPO11 initiator of meiotic double stranded breaks. (381 aa)
	zwilch	Zwilch kinetochore protein. (601 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (855 aa)
	iffo1	Intermediate filament family orphan 1b; Belongs to the intermediate filament family. (592 aa)
	MAU2	MAU2 sister chromatid cohesion factor. (598 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (358 aa)
	terf2	HTH myb-type domain-containing protein. (637 aa)
	acd	Uncharacterized protein. (471 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004083	LOC103358411	ENSSPAP00000004083	ENSSPAP00000011261	Telo_bind domain-containing protein.	TERF1 (TRF1)-interacting nuclear factor 2.	0.984
ENSSPAP00000004083	LOC103363335	ENSSPAP00000004083	ENSSPAP00000005231	Telo_bind domain-containing protein.	H2A histone family, member Y; Belongs to the histone H2A family.	0.657
ENSSPAP00000004083	LOC103366314	ENSSPAP00000004083	ENSSPAP00000013006	Telo_bind domain-containing protein.	Uncharacterized protein.	0.505
ENSSPAP00000004083	LOC103376442	ENSSPAP00000004083	ENSSPAP00000021230	Telo_bind domain-containing protein.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.657
ENSSPAP00000004083	RPA1	ENSSPAP00000004083	ENSSPAP00000014932	Telo_bind domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.584
ENSSPAP00000004083	acd	ENSSPAP00000004083	ENSSPAP00000022047	Telo_bind domain-containing protein.	Uncharacterized protein.	0.983
ENSSPAP00000004083	atrx	ENSSPAP00000004083	ENSSPAP00000016649	Telo_bind domain-containing protein.	ATRX chromatin remodeler.	0.505
ENSSPAP00000004083	rpa1	ENSSPAP00000004083	ENSSPAP00000013058	Telo_bind domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.584
ENSSPAP00000004083	terf2	ENSSPAP00000004083	ENSSPAP00000023503	Telo_bind domain-containing protein.	HTH myb-type domain-containing protein.	0.961
ENSSPAP00000004083	znf827	ENSSPAP00000004083	ENSSPAP00000004164	Telo_bind domain-containing protein.	Zinc finger protein 827.	0.406
ENSSPAP00000006493	LOC103354451	ENSSPAP00000006493	ENSSPAP00000004073	Uncharacterized protein.	Transcription activation suppressor b.	0.403
ENSSPAP00000006493	LOC103357611	ENSSPAP00000006493	ENSSPAP00000030740	Uncharacterized protein.	MAU2 sister chromatid cohesion factor.	0.884
ENSSPAP00000006493	LOC103361134	ENSSPAP00000006493	ENSSPAP00000009792	Uncharacterized protein.	WAPL cohesin release factor b.	0.820
ENSSPAP00000006493	LOC103361657	ENSSPAP00000006493	ENSSPAP00000006614	Uncharacterized protein.	Nipped-B protein.	0.900
ENSSPAP00000006493	LOC103366314	ENSSPAP00000006493	ENSSPAP00000013006	Uncharacterized protein.	Uncharacterized protein.	0.564
ENSSPAP00000006493	MAU2	ENSSPAP00000006493	ENSSPAP00000024193	Uncharacterized protein.	MAU2 sister chromatid cohesion factor.	0.884
ENSSPAP00000006493	atrx	ENSSPAP00000006493	ENSSPAP00000016649	Uncharacterized protein.	ATRX chromatin remodeler.	0.564
ENSSPAP00000006493	wapl	ENSSPAP00000006493	ENSSPAP00000022680	Uncharacterized protein.	WAPL cohesin release factor a.	0.820
ENSSPAP00000006942	ENSSPAP00000017877	ENSSPAP00000006942	ENSSPAP00000017877	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.819
ENSSPAP00000006942	LOC103363335	ENSSPAP00000006942	ENSSPAP00000005231	ANK_REP_REGION domain-containing protein.	H2A histone family, member Y; Belongs to the histone H2A family.	0.536