(15 nodes) Regulation of hippo signaling network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ajuba	Ajuba LIM protein. (730 aa)
	wtip	Uncharacterized protein. (616 aa)
	LOC103368777	Vestigial-like family member 4a. (261 aa)
	ENSSPAP00000026008	PDZ domain-containing protein. (225 aa)
	LOC103358706	Coronin; Belongs to the WD repeat coronin family. (930 aa)
	LOC103369863	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1983 aa)
	ENSSPAP00000022145	FERM_f0 domain-containing protein. (131 aa)
	LOC103370367	Neurofibromin 2b (merlin). (589 aa)
	ENSSPAP00000021286	FERM domain-containing protein. (84 aa)
	LOC103366906	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1956 aa)
	LOC103369651	SCHIP-1 domain-containing protein. (507 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2028 aa)
	LOC103358998	Citron rho-interacting serine/threonine kinase b. (1599 aa)
	vgll4	Vestigial-like family member 4b. (318 aa)
	LOC103374096	WT1 interacting protein. (679 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000021286	LOC103369651	ENSSPAP00000021286	ENSSPAP00000016429	FERM domain-containing protein.	SCHIP-1 domain-containing protein.	0.466
ENSSPAP00000021286	LOC103370367	ENSSPAP00000021286	ENSSPAP00000021848	FERM domain-containing protein.	Neurofibromin 2b (merlin).	0.832
ENSSPAP00000022145	ENSSPAP00000026008	ENSSPAP00000022145	ENSSPAP00000026008	FERM_f0 domain-containing protein.	PDZ domain-containing protein.	0.881
ENSSPAP00000022145	LOC103358998	ENSSPAP00000022145	ENSSPAP00000010962	FERM_f0 domain-containing protein.	Citron rho-interacting serine/threonine kinase b.	0.404
ENSSPAP00000022145	LOC103366906	ENSSPAP00000022145	ENSSPAP00000017628	FERM_f0 domain-containing protein.	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.404
ENSSPAP00000022145	LOC103369863	ENSSPAP00000022145	ENSSPAP00000024797	FERM_f0 domain-containing protein.	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	0.703
ENSSPAP00000022145	dlg5	ENSSPAP00000022145	ENSSPAP00000011567	FERM_f0 domain-containing protein.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.703
ENSSPAP00000026008	ENSSPAP00000022145	ENSSPAP00000026008	ENSSPAP00000022145	PDZ domain-containing protein.	FERM_f0 domain-containing protein.	0.881
ENSSPAP00000026008	LOC103369863	ENSSPAP00000026008	ENSSPAP00000024797	PDZ domain-containing protein.	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	0.485
ENSSPAP00000026008	dlg5	ENSSPAP00000026008	ENSSPAP00000011567	PDZ domain-containing protein.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.485
LOC103358998	ENSSPAP00000022145	ENSSPAP00000010962	ENSSPAP00000022145	Citron rho-interacting serine/threonine kinase b.	FERM_f0 domain-containing protein.	0.404
LOC103358998	LOC103369863	ENSSPAP00000010962	ENSSPAP00000024797	Citron rho-interacting serine/threonine kinase b.	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	0.464
LOC103358998	dlg5	ENSSPAP00000010962	ENSSPAP00000011567	Citron rho-interacting serine/threonine kinase b.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.464
LOC103366906	ENSSPAP00000022145	ENSSPAP00000017628	ENSSPAP00000022145	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	FERM_f0 domain-containing protein.	0.404
LOC103366906	LOC103369863	ENSSPAP00000017628	ENSSPAP00000024797	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	0.464
LOC103366906	dlg5	ENSSPAP00000017628	ENSSPAP00000011567	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.464
LOC103369651	ENSSPAP00000021286	ENSSPAP00000016429	ENSSPAP00000021286	SCHIP-1 domain-containing protein.	FERM domain-containing protein.	0.466
LOC103369651	LOC103370367	ENSSPAP00000016429	ENSSPAP00000021848	SCHIP-1 domain-containing protein.	Neurofibromin 2b (merlin).	0.466
LOC103369863	ENSSPAP00000022145	ENSSPAP00000024797	ENSSPAP00000022145	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	FERM_f0 domain-containing protein.	0.703
LOC103369863	ENSSPAP00000026008	ENSSPAP00000024797	ENSSPAP00000026008	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family.	PDZ domain-containing protein.	0.485