63 items (Stegastes partitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000030043	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (384 aa)
	LOC103357680	Uncharacterized protein. (411 aa)
	LOC103369401	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (181 aa)
	LOC103364879	Coenzyme Q8B. (635 aa)
	LOC103369991	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
	sirt6	Sirtuin 6. (349 aa)
	srd5a1	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
	LOC103367215	Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (516 aa)
	tpi1	Triosephosphate isomerase. (235 aa)
	hsd17b3	Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
	kmo	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (471 aa)
	aadat	Aminoadipate aminotransferase. (425 aa)
	coq9	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (336 aa)
	kyat1	Kynurenine aminotransferase 1. (445 aa)
	vkorc1	Vitamin K epoxide reductase complex, subunit 1. (167 aa)
	tdo2	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (399 aa)
	hsd17b10	Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
	pdss1	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (357 aa)
	pnkd	PNKD metallo-beta-lactamase domain containing. (359 aa)
	ENSSPAP00000009637	Flavodoxin_2 domain-containing protein. (134 aa)
	ndufa9	NADH:ubiquinone oxidoreductase subunit A9a. (381 aa)
	park7	Parkinson protein 7. (189 aa)
	ubiad1	UbiA prenyltransferase domain containing 1. (350 aa)
	srd5a2	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
	LOC103352943	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (436 aa)
	aifm2	Apoptosis inducing factor mitochondria associated 2. (372 aa)
	coq4	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (289 aa)
	got2	Aspartate aminotransferase. (428 aa)
	kyat3	Kynurenine aminotransferase 3. (409 aa)
	coq6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (483 aa)
	HAGHL	Hydroxyacylglutathione hydrolase like. (277 aa)
	hagh	Hydroxyacylglutathione hydrolase. (309 aa)
	coq10b	Coenzyme Q10B. (238 aa)
	GLO1	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
	afmid	Arylformamidase. (293 aa)
	LOC103362327	Indoleamine 2,3-dioxygenase 1. (414 aa)
	gatd1	Glutamine amidotransferase like class 1 domain containing 1. (218 aa)
	LOC103366846	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (414 aa)
	aldh8a1	Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
	coq8a	ABC1 domain-containing protein. (655 aa)
	coq2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (369 aa)
	LOC103356835	Triosephosphate isomerase. (248 aa)
	LOC103361881	Flavodoxin_2 domain-containing protein. (278 aa)
	ENSSPAP00000021279	Uncharacterized protein. (164 aa)
	LOC103357432	Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4. (489 aa)
	coq5	Coenzyme Q5, methyltransferase. (288 aa)
	coq7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (222 aa)
	LOC103365267	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (515 aa)
	vkorc1l1	Vitamin K epoxide reductase complex, subunit 1-like 1. (186 aa)
	hsd11b2	Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (405 aa)
	LOC103364192	Coenzyme Q8A, genome duplicate b. (599 aa)
	coq10a	Coenzyme Q10A. (249 aa)
	coq3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (338 aa)
	LOC103368151	Si:ch73-141c7.1. (232 aa)
	LOC103354354	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (419 aa)
	glod4	Glyoxalase domain containing 4. (298 aa)
	cryzl1	Crystallin, zeta (quinone reductase)-like 1. (358 aa)
	ENSSPAP00000030049	Carbonyl reductase 1. (297 aa)
	LOC103370935	Uncharacterized protein. (220 aa)
	LOC103370934	Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
	kdsr	3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000009637	kyat1	ENSSPAP00000009637	ENSSPAP00000007724	Flavodoxin_2 domain-containing protein.	Kynurenine aminotransferase 1.	0.521
ENSSPAP00000009637	kyat3	ENSSPAP00000009637	ENSSPAP00000012404	Flavodoxin_2 domain-containing protein.	Kynurenine aminotransferase 3.	0.521
ENSSPAP00000009637	ndufa9	ENSSPAP00000009637	ENSSPAP00000009693	Flavodoxin_2 domain-containing protein.	NADH:ubiquinone oxidoreductase subunit A9a.	0.667
ENSSPAP00000009637	ubiad1	ENSSPAP00000009637	ENSSPAP00000010093	Flavodoxin_2 domain-containing protein.	UbiA prenyltransferase domain containing 1.	0.839
ENSSPAP00000009637	vkorc1	ENSSPAP00000009637	ENSSPAP00000007754	Flavodoxin_2 domain-containing protein.	Vitamin K epoxide reductase complex, subunit 1.	0.875
ENSSPAP00000009637	vkorc1l1	ENSSPAP00000009637	ENSSPAP00000023951	Flavodoxin_2 domain-containing protein.	Vitamin K epoxide reductase complex, subunit 1-like 1.	0.859
ENSSPAP00000021279	ENSSPAP00000030043	ENSSPAP00000021279	ENSSPAP00000030043	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.426
ENSSPAP00000021279	ENSSPAP00000030049	ENSSPAP00000021279	ENSSPAP00000030049	Uncharacterized protein.	Carbonyl reductase 1.	0.426
ENSSPAP00000021279	LOC103356835	ENSSPAP00000021279	ENSSPAP00000018380	Uncharacterized protein.	Triosephosphate isomerase.	0.412
ENSSPAP00000021279	LOC103364192	ENSSPAP00000021279	ENSSPAP00000024617	Uncharacterized protein.	Coenzyme Q8A, genome duplicate b.	0.410
ENSSPAP00000021279	LOC103364879	ENSSPAP00000021279	ENSSPAP00000001032	Uncharacterized protein.	Coenzyme Q8B.	0.531
ENSSPAP00000021279	LOC103368151	ENSSPAP00000021279	ENSSPAP00000027581	Uncharacterized protein.	Si:ch73-141c7.1.	0.504
ENSSPAP00000021279	LOC103370934	ENSSPAP00000021279	ENSSPAP00000030063	Uncharacterized protein.	Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.426
ENSSPAP00000021279	LOC103370935	ENSSPAP00000021279	ENSSPAP00000030053	Uncharacterized protein.	Uncharacterized protein.	0.426
ENSSPAP00000021279	coq10a	ENSSPAP00000021279	ENSSPAP00000026052	Uncharacterized protein.	Coenzyme Q10A.	0.402
ENSSPAP00000021279	coq10b	ENSSPAP00000021279	ENSSPAP00000013779	Uncharacterized protein.	Coenzyme Q10B.	0.402
ENSSPAP00000021279	coq3	ENSSPAP00000021279	ENSSPAP00000026645	Uncharacterized protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.944
ENSSPAP00000021279	coq4	ENSSPAP00000021279	ENSSPAP00000012011	Uncharacterized protein.	Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.511
ENSSPAP00000021279	coq5	ENSSPAP00000021279	ENSSPAP00000021748	Uncharacterized protein.	Coenzyme Q5, methyltransferase.	0.928
ENSSPAP00000021279	coq6	ENSSPAP00000021279	ENSSPAP00000013443	Uncharacterized protein.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.904