(21 nodes) Regulation of tyrosine phosphorylation of STAT protein network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103372969	Uncharacterized protein. (896 aa)
	sh2b3	SH2B adaptor protein 3. (749 aa)
	LOC103361604	Interleukin 6 receptor. (579 aa)
	LOC103370039	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (432 aa)
	LOC103373247	Suppressor of cytokine signaling 3a. (205 aa)
	LOC103370062	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (356 aa)
	LOC103370644	CD40 molecule, TNF receptor superfamily member 5. (300 aa)
	arl2bp	ADP-ribosylation factor-like 2 binding protein. (177 aa)
	LOC103368476	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (166 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (350 aa)
	LOC103370704	Uncharacterized protein. (218 aa)
	LOC103356259	Poly [ADP-ribose] polymerase. (1774 aa)
	LOC103367871	Interleukin 19 like. (170 aa)
	socs1	Suppressor of cytokine signaling 1a. (204 aa)
	LOC103364670	Cytokine receptor-like factor 1a. (405 aa)
	ENSSPAP00000021286	FERM domain-containing protein. (84 aa)
	LOC103370367	Neurofibromin 2b (merlin). (589 aa)
	ENSSPAP00000021942	Cytokine receptor-like factor 1b. (429 aa)
	LOC103365293	Tumor necrosis factor receptor superfamily, member 1a. (336 aa)
	pibf1	Progesterone immunomodulatory binding factor 1. (765 aa)
	LOC103372658	Uncharacterized protein. (228 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000021286	LOC103370367	ENSSPAP00000021286	ENSSPAP00000021848	FERM domain-containing protein.	Neurofibromin 2b (merlin).	0.832
ENSSPAP00000021942	LOC103361604	ENSSPAP00000021942	ENSSPAP00000003759	Cytokine receptor-like factor 1b.	Interleukin 6 receptor.	0.603
ENSSPAP00000021942	LOC103372658	ENSSPAP00000021942	ENSSPAP00000029685	Cytokine receptor-like factor 1b.	Uncharacterized protein.	0.532
ENSSPAP00000021942	LOC103373247	ENSSPAP00000021942	ENSSPAP00000005259	Cytokine receptor-like factor 1b.	Suppressor of cytokine signaling 3a.	0.535
ENSSPAP00000021942	socs1	ENSSPAP00000021942	ENSSPAP00000020567	Cytokine receptor-like factor 1b.	Suppressor of cytokine signaling 1a.	0.520
LOC103361604	ENSSPAP00000021942	ENSSPAP00000003759	ENSSPAP00000021942	Interleukin 6 receptor.	Cytokine receptor-like factor 1b.	0.603
LOC103361604	LOC103364670	ENSSPAP00000003759	ENSSPAP00000020796	Interleukin 6 receptor.	Cytokine receptor-like factor 1a.	0.603
LOC103361604	LOC103365293	ENSSPAP00000003759	ENSSPAP00000024465	Interleukin 6 receptor.	Tumor necrosis factor receptor superfamily, member 1a.	0.525
LOC103361604	LOC103372658	ENSSPAP00000003759	ENSSPAP00000029685	Interleukin 6 receptor.	Uncharacterized protein.	0.723
LOC103361604	LOC103372969	ENSSPAP00000003759	ENSSPAP00000011218	Interleukin 6 receptor.	Uncharacterized protein.	0.994
LOC103361604	LOC103373247	ENSSPAP00000003759	ENSSPAP00000005259	Interleukin 6 receptor.	Suppressor of cytokine signaling 3a.	0.723
LOC103364670	LOC103361604	ENSSPAP00000020796	ENSSPAP00000003759	Cytokine receptor-like factor 1a.	Interleukin 6 receptor.	0.603
LOC103364670	LOC103372658	ENSSPAP00000020796	ENSSPAP00000029685	Cytokine receptor-like factor 1a.	Uncharacterized protein.	0.532
LOC103364670	LOC103373247	ENSSPAP00000020796	ENSSPAP00000005259	Cytokine receptor-like factor 1a.	Suppressor of cytokine signaling 3a.	0.535
LOC103364670	socs1	ENSSPAP00000020796	ENSSPAP00000020567	Cytokine receptor-like factor 1a.	Suppressor of cytokine signaling 1a.	0.520
LOC103365293	LOC103361604	ENSSPAP00000024465	ENSSPAP00000003759	Tumor necrosis factor receptor superfamily, member 1a.	Interleukin 6 receptor.	0.525
LOC103365293	LOC103370644	ENSSPAP00000024465	ENSSPAP00000008871	Tumor necrosis factor receptor superfamily, member 1a.	CD40 molecule, TNF receptor superfamily member 5.	0.561
LOC103367871	LOC103370704	ENSSPAP00000014756	ENSSPAP00000012426	Interleukin 19 like.	Uncharacterized protein.	0.863
LOC103370062	il12b	ENSSPAP00000005918	ENSSPAP00000011750	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.840
LOC103370367	ENSSPAP00000021286	ENSSPAP00000021848	ENSSPAP00000021286	Neurofibromin 2b (merlin).	FERM domain-containing protein.	0.832