(47 nodes) Regulation of carbohydrate biosynthetic process network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sirt7	Sirtuin 7. (407 aa)
	ppp1r3g	Si:ch211-152c8.5. (263 aa)
	igf2	Insulin-like growth factor 2b. (215 aa)
	sirt6	Sirtuin 6. (349 aa)
	ENSSPAP00000004940	Uncharacterized protein. (490 aa)
	LOC103373570	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
	ENSSPAP00000007645	Uncharacterized protein. (94 aa)
	gnmt	Glycine N-methyltransferase. (295 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	LOC103356172	Sphingomyelin phosphodiesterase 3, neutral. (516 aa)
	LOC103359525	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	ranbp2	RAN binding protein 2. (3063 aa)
	LOC103374137	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (384 aa)
	plek	Pleckstrin. (351 aa)
	LOC103357301	CBM21 domain-containing protein. (345 aa)
	ddb1	Damage-specific DNA binding protein 1. (1085 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1067 aa)
	ENSSPAP00000013416	Uncharacterized protein. (504 aa)
	ENSSPAP00000013615	Protein phosphatase 1, regulatory subunit 3Da. (294 aa)
	LOC103373573	Suppressor of glucose, autophagy associated 1. (1410 aa)
	ENSSPAP00000014362	Uncharacterized protein. (166 aa)
	LOC103355174	Family with sequence similarity 3 member C. (227 aa)
	ppp1r3b	Protein phosphatase 1 regulatory subunit. (266 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (365 aa)
	ENSSPAP00000017103	CBM21 domain-containing protein. (274 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	LOC103358541	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (520 aa)
	acadm	Uncharacterized protein. (422 aa)
	DGKQ	Diacylglycerol kinase theta. (678 aa)
	LOC103357653	Zgc:77112. (295 aa)
	LOC103371043	Uncharacterized protein. (161 aa)
	LOC103362117	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (476 aa)
	LOC103371563	E1A binding protein p300 a. (2869 aa)
	LOC103373263	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	ENSSPAP00000029022	Protein phosphatase 1, regulatory subunit 3Db. (265 aa)
	fam3a	Family with sequence similarity 3 member A. (228 aa)
	lepr	Leptin receptor. (1142 aa)
	ENSSPAP00000020318	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (450 aa)
	LOC103353121	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1684 aa)
	ENSSPAP00000021329	CBM21 domain-containing protein. (286 aa)
	ENSSPAP00000021681	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	ppp1r3c	Protein phosphatase 1 regulatory subunit. (346 aa)
	ep300	E1A binding protein p300 b. (2872 aa)
	pdgfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (569 aa)
	ENSSPAP00000026497	Ig-like domain-containing protein. (218 aa)
	LOC103371440	Protein phosphatase 1 regulatory subunit. (329 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004940	LOC103371563	ENSSPAP00000004940	ENSSPAP00000030493	Uncharacterized protein.	E1A binding protein p300 a.	0.418
ENSSPAP00000004940	ep300	ENSSPAP00000004940	ENSSPAP00000023258	Uncharacterized protein.	E1A binding protein p300 b.	0.418
ENSSPAP00000013416	LOC103371563	ENSSPAP00000013416	ENSSPAP00000030493	Uncharacterized protein.	E1A binding protein p300 a.	0.418
ENSSPAP00000013416	ep300	ENSSPAP00000013416	ENSSPAP00000023258	Uncharacterized protein.	E1A binding protein p300 b.	0.418
ENSSPAP00000013615	LOC103371440	ENSSPAP00000013615	ENSSPAP00000026774	Protein phosphatase 1, regulatory subunit 3Da.	Protein phosphatase 1 regulatory subunit.	0.545
ENSSPAP00000013615	ppp1r3b	ENSSPAP00000013615	ENSSPAP00000015821	Protein phosphatase 1, regulatory subunit 3Da.	Protein phosphatase 1 regulatory subunit.	0.677
ENSSPAP00000014362	LOC103373573	ENSSPAP00000014362	ENSSPAP00000014334	Uncharacterized protein.	Suppressor of glucose, autophagy associated 1.	0.900
ENSSPAP00000020318	LOC103373263	ENSSPAP00000020318	ENSSPAP00000030243	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.424
ENSSPAP00000020318	igf2	ENSSPAP00000020318	ENSSPAP00000002061	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Insulin-like growth factor 2b.	0.529
ENSSPAP00000020318	lepr	ENSSPAP00000020318	ENSSPAP00000020305	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Leptin receptor.	0.539
ENSSPAP00000020318	ogt	ENSSPAP00000020318	ENSSPAP00000013147	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1.	0.408
ENSSPAP00000026497	ddb1	ENSSPAP00000026497	ENSSPAP00000013106	Ig-like domain-containing protein.	Damage-specific DNA binding protein 1.	0.427
ENSSPAP00000026497	usp7	ENSSPAP00000026497	ENSSPAP00000017264	Ig-like domain-containing protein.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.438
ENSSPAP00000029022	LOC103371440	ENSSPAP00000029022	ENSSPAP00000026774	Protein phosphatase 1, regulatory subunit 3Db.	Protein phosphatase 1 regulatory subunit.	0.538
LOC103353121	LOC103359525	ENSSPAP00000021176	ENSSPAP00000010088	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.932
LOC103353121	LOC103373570	ENSSPAP00000021176	ENSSPAP00000006449	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.964
LOC103353121	cltc	ENSSPAP00000021176	ENSSPAP00000008062	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.932
LOC103353121	ranbp2	ENSSPAP00000021176	ENSSPAP00000010511	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	RAN binding protein 2.	0.562
LOC103356172	LOC103373570	ENSSPAP00000009180	ENSSPAP00000006449	Sphingomyelin phosphodiesterase 3, neutral.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.684
LOC103357301	LOC103371440	ENSSPAP00000011470	ENSSPAP00000026774	CBM21 domain-containing protein.	Protein phosphatase 1 regulatory subunit.	0.679