(32 nodes) Main axon network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cldn5	Claudin 5. (215 aa)
	LOC103375507	Aldo_ket_red domain-containing protein. (236 aa)
	LOC103370362	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (248 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (287 aa)
	LOC103363681	Sodium channel, voltage-gated, type I, beta a. (224 aa)
	ENSSPAP00000023472	Uncharacterized protein. (92 aa)
	cntn2	Contactin 2. (1040 aa)
	dagla	Diacylglycerol lipase, alpha. (1084 aa)
	LOC103374421	Uncharacterized protein. (318 aa)
	c9orf72	Zgc:100846. (462 aa)
	LOC103371882	Par-3 family cell polarity regulator alpha, b. (952 aa)
	LOC103373135	Peptidase S72 domain-containing protein. (881 aa)
	crhbp	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
	slc1a2	Solute carrier family 1 member 2b. (558 aa)
	LOC103356881	Potassium voltage-gated channel, shaker-related subfamily, beta member 1 b. (412 aa)
	PARD3	Par-3 family cell polarity regulator. (1308 aa)
	kcnab2	Potassium voltage-gated channel, shaker-related subfamily, beta member 2 a. (402 aa)
	ENSSPAP00000011020	Par3_HAL_N_term domain-containing protein. (63 aa)
	LOC103354448	Peptidase S72 domain-containing protein. (910 aa)
	hapln2	Hyaluronan and proteoglycan link protein 2. (341 aa)
	NAV1	Neuron navigator 1. (2287 aa)
	LOC103371033	Dystroglycan 1. (891 aa)
	ucn	Urotensin 1. (148 aa)
	LOC103368189	Amino acid transporter. (667 aa)
	mbp	Myelin basic protein b. (137 aa)
	LOC103366006	Amino acid transporter. (572 aa)
	ENSSPAP00000000108	Claudin 5b. (107 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (380 aa)
	LOC103357131	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC103355819	Neuron navigator 1b. (1800 aa)
	LOC103371680	Sodium channel, voltage-gated, type I, beta b. (221 aa)
	KCNAB3	Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (417 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000000108	LOC103357131	ENSSPAP00000000108	ENSSPAP00000001121	Claudin 5b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.503
ENSSPAP00000000108	cldn5	ENSSPAP00000000108	ENSSPAP00000020839	Claudin 5b.	Claudin 5.	0.503
ENSSPAP00000023472	LOC103371680	ENSSPAP00000023472	ENSSPAP00000002683	Uncharacterized protein.	Sodium channel, voltage-gated, type I, beta b.	0.914
LOC103354448	LOC103371033	ENSSPAP00000003995	ENSSPAP00000031011	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.933
LOC103357131	ENSSPAP00000000108	ENSSPAP00000001121	ENSSPAP00000000108	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 5b.	0.503
LOC103363681	LOC103371680	ENSSPAP00000023455	ENSSPAP00000002683	Sodium channel, voltage-gated, type I, beta a.	Sodium channel, voltage-gated, type I, beta b.	0.913
LOC103371033	LOC103354448	ENSSPAP00000031011	ENSSPAP00000003995	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.933
LOC103371680	ENSSPAP00000023472	ENSSPAP00000002683	ENSSPAP00000023472	Sodium channel, voltage-gated, type I, beta b.	Uncharacterized protein.	0.914
LOC103371680	LOC103363681	ENSSPAP00000002683	ENSSPAP00000023455	Sodium channel, voltage-gated, type I, beta b.	Sodium channel, voltage-gated, type I, beta a.	0.913
LOC103371882	PARD3	ENSSPAP00000012672	ENSSPAP00000020764	Par-3 family cell polarity regulator alpha, b.	Par-3 family cell polarity regulator.	0.819
LOC103374421	ucn	ENSSPAP00000028185	ENSSPAP00000029579	Uncharacterized protein.	Urotensin 1.	0.793
PARD3	LOC103371882	ENSSPAP00000020764	ENSSPAP00000012672	Par-3 family cell polarity regulator.	Par-3 family cell polarity regulator alpha, b.	0.819
cldn5	ENSSPAP00000000108	ENSSPAP00000020839	ENSSPAP00000000108	Claudin 5.	Claudin 5b.	0.503
crhbp	ucn	ENSSPAP00000018604	ENSSPAP00000029579	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urotensin 1.	0.793
ucn	LOC103374421	ENSSPAP00000029579	ENSSPAP00000028185	Urotensin 1.	Uncharacterized protein.	0.793
ucn	crhbp	ENSSPAP00000029579	ENSSPAP00000018604	Urotensin 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.793