(23 nodes) Positive regulation of heart contraction network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103375280	Transforming growth factor beta; Belongs to the TGF-beta family. (333 aa)
	LOC103358784	Endothelin 2. (162 aa)
	LOC103366682	Uncharacterized protein. (169 aa)
	adra1a	Adrenoceptor alpha 1Aa. (461 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (202 aa)
	ENSSPAP00000006281	Apelin receptor early endogenous ligand. (55 aa)
	LOC103374198	Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
	nkx2-5	NK2 homeobox 5. (318 aa)
	ADM2	Uncharacterized protein. (171 aa)
	ENSSPAP00000012557	Apelin. (77 aa)
	ENSSPAP00000012636	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	gch1	GTP cyclohydrolase 1. (320 aa)
	ENSSPAP00000012851	Uncharacterized protein. (127 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (630 aa)
	LOC103360796	GTP_cyclohydroI domain-containing protein. (246 aa)
	adm	Adrenomedullin a. (174 aa)
	LOC103366884	Ion_trans domain-containing protein; Belongs to the potassium channel family. (500 aa)
	adra1d	Adrenoceptor alpha 1D. (500 aa)
	adra1b	Adrenoceptor alpha 1Bb. (505 aa)
	tgfb2	Transforming growth factor, beta 2. (144 aa)
	LOC103373802	GTP cyclohydrolase 2. (226 aa)
	ENSSPAP00000025220	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (445 aa)
	ucn	Urotensin 1. (148 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADM2	LOC103366682	ENSSPAP00000012049	ENSSPAP00000000367	Uncharacterized protein.	Uncharacterized protein.	0.632
ADM2	adm	ENSSPAP00000012049	ENSSPAP00000016374	Uncharacterized protein.	Adrenomedullin a.	0.700
ENSSPAP00000006281	ENSSPAP00000012557	ENSSPAP00000006281	ENSSPAP00000012557	Apelin receptor early endogenous ligand.	Apelin.	0.575
ENSSPAP00000012557	ENSSPAP00000006281	ENSSPAP00000012557	ENSSPAP00000006281	Apelin.	Apelin receptor early endogenous ligand.	0.575
ENSSPAP00000012636	ENSSPAP00000012851	ENSSPAP00000012636	ENSSPAP00000012851	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.793
ENSSPAP00000012636	ENSSPAP00000025220	ENSSPAP00000012636	ENSSPAP00000025220	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.763
ENSSPAP00000012636	LOC103358784	ENSSPAP00000012636	ENSSPAP00000000111	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.483
ENSSPAP00000012636	adra1b	ENSSPAP00000012636	ENSSPAP00000018622	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor alpha 1Bb.	0.759
ENSSPAP00000012636	adra1d	ENSSPAP00000012636	ENSSPAP00000017621	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor alpha 1D.	0.757
ENSSPAP00000012851	ENSSPAP00000012636	ENSSPAP00000012851	ENSSPAP00000012636	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.793
ENSSPAP00000012851	ENSSPAP00000025220	ENSSPAP00000012851	ENSSPAP00000025220	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.770
ENSSPAP00000012851	LOC103358784	ENSSPAP00000012851	ENSSPAP00000000111	Uncharacterized protein.	Endothelin 2.	0.864
ENSSPAP00000012851	adra1a	ENSSPAP00000012851	ENSSPAP00000002916	Uncharacterized protein.	Adrenoceptor alpha 1Aa.	0.793
ENSSPAP00000012851	adra1b	ENSSPAP00000012851	ENSSPAP00000018622	Uncharacterized protein.	Adrenoceptor alpha 1Bb.	0.770
ENSSPAP00000012851	adra1d	ENSSPAP00000012851	ENSSPAP00000017621	Uncharacterized protein.	Adrenoceptor alpha 1D.	0.770
ENSSPAP00000012851	tgfb2	ENSSPAP00000012851	ENSSPAP00000021337	Uncharacterized protein.	Transforming growth factor, beta 2.	0.502
ENSSPAP00000025220	ENSSPAP00000012636	ENSSPAP00000025220	ENSSPAP00000012636	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.763
ENSSPAP00000025220	ENSSPAP00000012851	ENSSPAP00000025220	ENSSPAP00000012851	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.770
ENSSPAP00000025220	LOC103358784	ENSSPAP00000025220	ENSSPAP00000000111	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.463
ENSSPAP00000025220	adra1a	ENSSPAP00000025220	ENSSPAP00000002916	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor alpha 1Aa.	0.761