(49 nodes) Positive regulation of mitotic cell cycle network (Stegastes partitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdt1	Chromatin licensing and DNA replication factor 1. (595 aa)
	sass6	SAS-6 centriolar assembly protein. (583 aa)
	ttl	Uncharacterized protein. (383 aa)
	cdc7	Cell division cycle 7 homolog (S. cerevisiae). (617 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (605 aa)
	mtbp	MDM2 binding protein. (878 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (690 aa)
	LOC103360542	ADAM metallopeptidase domain 17a. (876 aa)
	mblac1	Metallo-beta-lactamase domain containing 1. (218 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (810 aa)
	rb1	Retinoblastoma 1. (909 aa)
	LOC103374609	Uncharacterized protein; Belongs to the cyclin family. (278 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (766 aa)
	mecp2	Methyl CpG binding protein 2. (974 aa)
	LOC103374064	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (296 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	rad51c	RAD51 paralog C. (338 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (340 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (121 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (857 aa)
	LOC103363473	Regulator of cell cycle. (126 aa)
	kmt2e	Lysine (K)-specific methyltransferase 2E. (1212 aa)
	ENSSPAP00000014994	MAD2L1 binding protein. (235 aa)
	LOC103362330	NK3 homeobox 1. (192 aa)
	cdc27	Cell division cycle 27. (803 aa)
	ENSSPAP00000017877	Uncharacterized protein. (1285 aa)
	anapc5	Anaphase promoting complex subunit 5. (773 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	CDC25B	Cell division cycle 25B. (573 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	lgmn	Legumain. (436 aa)
	LOC103376074	Cyclin D2, a; Belongs to the cyclin family. (383 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1255 aa)
	LOC103371395	ADAM metallopeptidase domain 17b. (836 aa)
	LOC103371396	Cleavage and polyadenylation specific factor 3. (686 aa)
	ccnd2	Cyclin D2, b; Belongs to the cyclin family. (294 aa)
	plrg1	Pleiotropic regulator 1. (513 aa)
	cul3	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	LOC103371455	Homeobox protein Nkx-3.1-like. (192 aa)
	ENSSPAP00000027283	Cell division cycle associated 5. (251 aa)
	ENSSPAP00000027748	MBD domain-containing protein. (314 aa)
	stox1	Storkhead box 1. (1103 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	ccnd1	Cyclin D1; Belongs to the cyclin family. (292 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
	stil	STIL centriolar assembly protein. (900 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (396 aa)
	ENSSPAP00000000551	Cell division cycle associated 5. (251 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC25B	CUL3	ENSSPAP00000019631	ENSSPAP00000019914	Cell division cycle 25B.	Cullin 3; Belongs to the cullin family.	0.453
CDC25B	LOC103374064	ENSSPAP00000019631	ENSSPAP00000007005	Cell division cycle 25B.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.775
CDC25B	LOC103374609	ENSSPAP00000019631	ENSSPAP00000006516	Cell division cycle 25B.	Uncharacterized protein; Belongs to the cyclin family.	0.775
CDC25B	LOC103376074	ENSSPAP00000019631	ENSSPAP00000021683	Cell division cycle 25B.	Cyclin D2, a; Belongs to the cyclin family.	0.775
CDC25B	ccnd1	ENSSPAP00000019631	ENSSPAP00000029133	Cell division cycle 25B.	Cyclin D1; Belongs to the cyclin family.	0.775
CDC25B	ccnd2	ENSSPAP00000019631	ENSSPAP00000025944	Cell division cycle 25B.	Cyclin D2, b; Belongs to the cyclin family.	0.775
CDC25B	cdc27	ENSSPAP00000019631	ENSSPAP00000015941	Cell division cycle 25B.	Cell division cycle 27.	0.544
CDC25B	cul3	ENSSPAP00000019631	ENSSPAP00000026553	Cell division cycle 25B.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.453
CPSF3	LOC103371396	ENSSPAP00000003801	ENSSPAP00000024576	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 3.	0.898
CPSF3	LSM10	ENSSPAP00000003801	ENSSPAP00000012154	Cleavage and polyadenylation specific factor 3.	LSM10, U7 small nuclear RNA associated.	0.912
CPSF3	cdc23	ENSSPAP00000003801	ENSSPAP00000003367	Cleavage and polyadenylation specific factor 3.	CDC23 (cell division cycle 23, yeast, homolog).	0.430
CPSF3	cdc27	ENSSPAP00000003801	ENSSPAP00000015941	Cleavage and polyadenylation specific factor 3.	Cell division cycle 27.	0.463
CPSF3	lsm11	ENSSPAP00000003801	ENSSPAP00000011526	Cleavage and polyadenylation specific factor 3.	LSM11, U7 small nuclear RNA associated.	0.584
CUL3	CDC25B	ENSSPAP00000019914	ENSSPAP00000019631	Cullin 3; Belongs to the cullin family.	Cell division cycle 25B.	0.453
CUL3	LOC103374064	ENSSPAP00000019914	ENSSPAP00000007005	Cullin 3; Belongs to the cullin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.703
CUL3	LOC103374609	ENSSPAP00000019914	ENSSPAP00000006516	Cullin 3; Belongs to the cullin family.	Uncharacterized protein; Belongs to the cyclin family.	0.703
CUL3	LOC103376074	ENSSPAP00000019914	ENSSPAP00000021683	Cullin 3; Belongs to the cullin family.	Cyclin D2, a; Belongs to the cyclin family.	0.703
CUL3	ccnd1	ENSSPAP00000019914	ENSSPAP00000029133	Cullin 3; Belongs to the cullin family.	Cyclin D1; Belongs to the cyclin family.	0.703
CUL3	ccnd2	ENSSPAP00000019914	ENSSPAP00000025944	Cullin 3; Belongs to the cullin family.	Cyclin D2, b; Belongs to the cyclin family.	0.703
CUL3	cdc27	ENSSPAP00000019914	ENSSPAP00000015941	Cullin 3; Belongs to the cullin family.	Cell division cycle 27.	0.508