(57 nodes) Polyol biosynthetic process network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103376306	6-pyruvoyltetrahydropterin synthase. (149 aa)
	LOC103376559	Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (510 aa)
	LOC103357664	Glutamic-oxaloacetic transaminase 1 like 1. (430 aa)
	ip6k2	Kinase; Belongs to the inositol phosphokinase (IPK) family. (516 aa)
	ENSSPAP00000000603	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha. (115 aa)
	LOC103368841	Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (521 aa)
	ENSSPAP00000003990	Si:dkey-91i10.3. (284 aa)
	ENSSPAP00000003997	Uncharacterized protein. (171 aa)
	ENSSPAP00000004425	Uncharacterized protein. (336 aa)
	itpka	Kinase; Belongs to the inositol phosphokinase (IPK) family. (451 aa)
	sphk1	DAGKc domain-containing protein. (357 aa)
	ENSSPAP00000004714	DAGKc domain-containing protein. (236 aa)
	ENSSPAP00000004718	Uncharacterized protein. (455 aa)
	LOC103356684	Inositol-1-monophosphatase. (272 aa)
	LOC103356683	Inositol-1-monophosphatase. (284 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (597 aa)
	impad1	Inositol monophosphatase domain containing 1. (344 aa)
	sptlc1	Serine palmitoyltransferase, long chain base subunit 1. (472 aa)
	ENSSPAP00000009652	Kinase; Belongs to the inositol phosphokinase (IPK) family. (280 aa)
	LOC103372280	Uncharacterized protein; Belongs to the cytochrome P450 family. (193 aa)
	ip6k1	Kinase; Belongs to the inositol phosphokinase (IPK) family. (475 aa)
	itpkc	Kinase; Belongs to the inositol phosphokinase (IPK) family. (684 aa)
	asah2	Neutral ceramidase. (511 aa)
	ENSSPAP00000012265	Uncharacterized protein. (181 aa)
	gch1	GTP cyclohydrolase 1. (320 aa)
	ENSSPAP00000012925	Kinase; Belongs to the inositol phosphokinase (IPK) family. (356 aa)
	LOC103363468	Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (514 aa)
	tmem130	Transmembrane protein 130. (305 aa)
	PTS	6-pyruvoyl tetrahydrobiopterin synthase-like. (149 aa)
	ipmk	Kinase; Belongs to the inositol phosphokinase (IPK) family. (496 aa)
	SPHK1	Sphingosine kinase 1. (380 aa)
	LOC103360796	GTP_cyclohydroI domain-containing protein. (246 aa)
	qdpr	Quinoid dihydropteridine reductase a. (236 aa)
	itpkb	Kinase; Belongs to the inositol phosphokinase (IPK) family. (444 aa)
	asah1	N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (392 aa)
	got1	Aspartate aminotransferase. (415 aa)
	LOC103366966	Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (541 aa)
	ENSSPAP00000022452	Ceramidse_alk_C domain-containing protein. (141 aa)
	ptafr	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
	acer3	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
	PCBD2	Pterin-4 alpha-carbinolamine dehydratase 2. (137 aa)
	LOC103373802	GTP cyclohydrolase 2. (226 aa)
	dhfr	Dihydrofolate reductase. (187 aa)
	LOC103358728	Kinase; Belongs to the inositol phosphokinase (IPK) family. (465 aa)
	ippk	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (480 aa)
	GOT1	Aspartate aminotransferase. (354 aa)
	LOC103366222	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1187 aa)
	acer1	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (282 aa)
	ISYNA1	Inositol-3-phosphate synthase 1. (552 aa)
	pck2	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (595 aa)
	gba	Glucosylceramidase. (411 aa)
	spr	Sepiapterin reductase b. (267 aa)
	ppip5k1	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1428 aa)
	LOC103360265	Inositol-1-monophosphatase. (275 aa)
	LOC103360266	Inositol-1-monophosphatase. (288 aa)
	LOC103371587	Dihydrofolate reductase. (177 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000000603	ENSSPAP00000012265	ENSSPAP00000000603	ENSSPAP00000012265	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Uncharacterized protein.	0.629
ENSSPAP00000000603	GOT1	ENSSPAP00000000603	ENSSPAP00000026519	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Aspartate aminotransferase.	0.583
ENSSPAP00000000603	LOC103357664	ENSSPAP00000000603	ENSSPAP00000000129	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Glutamic-oxaloacetic transaminase 1 like 1.	0.583
ENSSPAP00000000603	LOC103376306	ENSSPAP00000000603	ENSSPAP00000001719	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	6-pyruvoyltetrahydropterin synthase.	0.402
ENSSPAP00000000603	PCBD2	ENSSPAP00000000603	ENSSPAP00000023948	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Pterin-4 alpha-carbinolamine dehydratase 2.	0.836
ENSSPAP00000000603	PTS	ENSSPAP00000000603	ENSSPAP00000014268	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	6-pyruvoyl tetrahydrobiopterin synthase-like.	0.402
ENSSPAP00000000603	got1	ENSSPAP00000000603	ENSSPAP00000017865	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Aspartate aminotransferase.	0.583
ENSSPAP00000000603	qdpr	ENSSPAP00000000603	ENSSPAP00000016441	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Quinoid dihydropteridine reductase a.	0.914
ENSSPAP00000000603	spr	ENSSPAP00000000603	ENSSPAP00000030038	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.	Sepiapterin reductase b.	0.629
ENSSPAP00000003990	ENSSPAP00000003997	ENSSPAP00000003990	ENSSPAP00000003997	Si:dkey-91i10.3.	Uncharacterized protein.	0.723
ENSSPAP00000003990	ENSSPAP00000012265	ENSSPAP00000003990	ENSSPAP00000012265	Si:dkey-91i10.3.	Uncharacterized protein.	0.466
ENSSPAP00000003990	LOC103363468	ENSSPAP00000003990	ENSSPAP00000013214	Si:dkey-91i10.3.	Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family.	0.774
ENSSPAP00000003990	LOC103372280	ENSSPAP00000003990	ENSSPAP00000010114	Si:dkey-91i10.3.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.621
ENSSPAP00000003990	qdpr	ENSSPAP00000003990	ENSSPAP00000016441	Si:dkey-91i10.3.	Quinoid dihydropteridine reductase a.	0.490
ENSSPAP00000003990	spr	ENSSPAP00000003990	ENSSPAP00000030038	Si:dkey-91i10.3.	Sepiapterin reductase b.	0.466
ENSSPAP00000003997	ENSSPAP00000003990	ENSSPAP00000003997	ENSSPAP00000003990	Uncharacterized protein.	Si:dkey-91i10.3.	0.723
ENSSPAP00000003997	ENSSPAP00000012265	ENSSPAP00000003997	ENSSPAP00000012265	Uncharacterized protein.	Uncharacterized protein.	0.466
ENSSPAP00000003997	LOC103363468	ENSSPAP00000003997	ENSSPAP00000013214	Uncharacterized protein.	Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family.	0.774
ENSSPAP00000003997	qdpr	ENSSPAP00000003997	ENSSPAP00000016441	Uncharacterized protein.	Quinoid dihydropteridine reductase a.	0.490
ENSSPAP00000003997	spr	ENSSPAP00000003997	ENSSPAP00000030038	Uncharacterized protein.	Sepiapterin reductase b.	0.466