(21 nodes) Mesodermal cell differentiation network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	itgb4	Integrin beta. (1992 aa)
	bmp2	Bone morphogenetic protein 2b. (416 aa)
	LOC103363029	Lysine (K)-specific demethylase 6B, b. (1760 aa)
	taf10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
	LOC103371952	Uncharacterized protein. (341 aa)
	lclat1	Lysocardiolipin acyltransferase 1. (385 aa)
	kdm6a	Lysine (K)-specific demethylase 6A. (1461 aa)
	LOC103363664	Lysine (K)-specific demethylase 6A, like. (1499 aa)
	ENSSPAP00000021526	BHLH domain-containing protein. (108 aa)
	LOC103365158	T-cell acute lymphocytic leukemia 1. (388 aa)
	ENSSPAP00000018240	Uncharacterized protein. (124 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	kdm6b	Lysine (K)-specific demethylase 6B, a. (2264 aa)
	msgn1	Mesogenin 1. (146 aa)
	foxh1	Forkhead box H1. (520 aa)
	LOC103362742	Uncharacterized protein. (120 aa)
	LOC103372955	Integrin, alpha 3b; Belongs to the integrin alpha chain family. (1056 aa)
	ENSSPAP00000011206	High mobility group AT-hook 2. (108 aa)
	LOC103355704	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	LOC103369576	Visual system homeobox 1 homolog, chx10-like. (351 aa)
	LOC103355705	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000018240	bmp2	ENSSPAP00000018240	ENSSPAP00000015145	Uncharacterized protein.	Bone morphogenetic protein 2b.	0.417
ENSSPAP00000018240	itgb4	ENSSPAP00000018240	ENSSPAP00000015101	Uncharacterized protein.	Integrin beta.	0.930
LOC103355704	LOC103371952	ENSSPAP00000012022	ENSSPAP00000026984	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.875
LOC103355704	bmp2	ENSSPAP00000012022	ENSSPAP00000015145	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 2b.	0.440
LOC103355704	sfrp2	ENSSPAP00000012022	ENSSPAP00000015452	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.847
LOC103355705	LOC103371952	ENSSPAP00000012070	ENSSPAP00000026984	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.847
LOC103355705	bmp2	ENSSPAP00000012070	ENSSPAP00000015145	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 2b.	0.440
LOC103355705	sfrp2	ENSSPAP00000012070	ENSSPAP00000015452	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.847
LOC103363029	LOC103363664	ENSSPAP00000028525	ENSSPAP00000022874	Lysine (K)-specific demethylase 6B, b.	Lysine (K)-specific demethylase 6A, like.	0.795
LOC103363029	kdm6a	ENSSPAP00000028525	ENSSPAP00000023742	Lysine (K)-specific demethylase 6B, b.	Lysine (K)-specific demethylase 6A.	0.786
LOC103363029	kdm6b	ENSSPAP00000028525	ENSSPAP00000000058	Lysine (K)-specific demethylase 6B, b.	Lysine (K)-specific demethylase 6B, a.	0.786
LOC103363664	LOC103363029	ENSSPAP00000022874	ENSSPAP00000028525	Lysine (K)-specific demethylase 6A, like.	Lysine (K)-specific demethylase 6B, b.	0.795
LOC103363664	kdm6a	ENSSPAP00000022874	ENSSPAP00000023742	Lysine (K)-specific demethylase 6A, like.	Lysine (K)-specific demethylase 6A.	0.789
LOC103363664	kdm6b	ENSSPAP00000022874	ENSSPAP00000000058	Lysine (K)-specific demethylase 6A, like.	Lysine (K)-specific demethylase 6B, a.	0.786
LOC103371952	LOC103355704	ENSSPAP00000026984	ENSSPAP00000012022	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.875
LOC103371952	LOC103355705	ENSSPAP00000026984	ENSSPAP00000012070	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.847
LOC103372955	bmp2	ENSSPAP00000010763	ENSSPAP00000015145	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Bone morphogenetic protein 2b.	0.417
LOC103372955	itgb4	ENSSPAP00000010763	ENSSPAP00000015101	Integrin, alpha 3b; Belongs to the integrin alpha chain family.	Integrin beta.	0.953
bmp2	ENSSPAP00000018240	ENSSPAP00000015145	ENSSPAP00000018240	Bone morphogenetic protein 2b.	Uncharacterized protein.	0.417
bmp2	LOC103355704	ENSSPAP00000015145	ENSSPAP00000012022	Bone morphogenetic protein 2b.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.440