(13 nodes) Sympathetic nervous system development network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (451 aa)
	LOC103371090	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (805 aa)
	hand2	Heart and neural crest derivatives expressed 2. (218 aa)
	utp25	UTP25 small subunit processor component. (753 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	LOC103357368	Neuropilin; Belongs to the neuropilin family. (846 aa)
	LOC103362426	Endothelin receptor type Ab. (313 aa)
	LOC103368088	Neuropilin; Belongs to the neuropilin family. (932 aa)
	LOC103360486	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	phox2a	Paired like homeobox 2A. (301 aa)
	ENSSPAP00000004600	Achaete-scute family bHLH transcription factor 1a. (166 aa)
	nf1	Neurofibromin 1b. (2780 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004600	phox2a	ENSSPAP00000004600	ENSSPAP00000026758	Achaete-scute family bHLH transcription factor 1a.	Paired like homeobox 2A.	0.419
ENSSPAP00000004600	phox2b	ENSSPAP00000004600	ENSSPAP00000013919	Achaete-scute family bHLH transcription factor 1a.	Paired like homeobox 2Bb.	0.410
LOC103357368	LOC103360486	ENSSPAP00000017181	ENSSPAP00000026447	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.522
LOC103357368	LOC103371090	ENSSPAP00000017181	ENSSPAP00000001599	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.522
LOC103360486	LOC103357368	ENSSPAP00000026447	ENSSPAP00000017181	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.522
LOC103360486	LOC103368088	ENSSPAP00000026447	ENSSPAP00000024613	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.522
LOC103362426	ednra	ENSSPAP00000018883	ENSSPAP00000004293	Endothelin receptor type Ab.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.899
LOC103368088	LOC103360486	ENSSPAP00000024613	ENSSPAP00000026447	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.522
LOC103368088	LOC103371090	ENSSPAP00000024613	ENSSPAP00000001599	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.522
LOC103371090	LOC103357368	ENSSPAP00000001599	ENSSPAP00000017181	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.522
LOC103371090	LOC103368088	ENSSPAP00000001599	ENSSPAP00000024613	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.522
ednra	LOC103362426	ENSSPAP00000004293	ENSSPAP00000018883	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab.	0.899
gdnf	phox2b	ENSSPAP00000007887	ENSSPAP00000013919	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	Paired like homeobox 2Bb.	0.414
hand2	phox2a	ENSSPAP00000001453	ENSSPAP00000026758	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2A.	0.532
hand2	phox2b	ENSSPAP00000001453	ENSSPAP00000013919	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2Bb.	0.563
phox2a	ENSSPAP00000004600	ENSSPAP00000026758	ENSSPAP00000004600	Paired like homeobox 2A.	Achaete-scute family bHLH transcription factor 1a.	0.419
phox2a	hand2	ENSSPAP00000026758	ENSSPAP00000001453	Paired like homeobox 2A.	Heart and neural crest derivatives expressed 2.	0.532
phox2b	ENSSPAP00000004600	ENSSPAP00000013919	ENSSPAP00000004600	Paired like homeobox 2Bb.	Achaete-scute family bHLH transcription factor 1a.	0.410
phox2b	gdnf	ENSSPAP00000013919	ENSSPAP00000007887	Paired like homeobox 2Bb.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.414
phox2b	hand2	ENSSPAP00000013919	ENSSPAP00000001453	Paired like homeobox 2Bb.	Heart and neural crest derivatives expressed 2.	0.563