(20 nodes) Neuromast development network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	llgl2	LLGL scribble cell polarity complex component 2. (1004 aa)
	LOC103358343	Transmembrane protein 132E. (1078 aa)
	LOC103367232	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	LOC103356627	Transmembrane channel-like protein. (826 aa)
	ENSSPAP00000000647	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	LOC103368826	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	wnt5b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	LOC103353817	R-spondin 3. (340 aa)
	LOC103367097	Vang-like protein. (525 aa)
	LOC103372127	Transmembrane O-methyltransferase. (259 aa)
	znrf3	Zinc and ring finger 3. (896 aa)
	LOC103369234	Vang-like protein. (526 aa)
	slc44a4	Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (717 aa)
	scrib	Scribble planar cell polarity protein. (1689 aa)
	LOC103363483	Mothers against decapentaplegic homolog. (476 aa)
	LOC103373543	Neurogenin 1. (194 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
	neurod1	Neurogenic differentiation factor. (356 aa)
	abhd12	Abhydrolase domain containing 12. (318 aa)
	lrrc1	Leucine rich repeat containing 1. (525 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103353817	znrf3	ENSSPAP00000028891	ENSSPAP00000021717	R-spondin 3.	Zinc and ring finger 3.	0.968
LOC103363483	znrf3	ENSSPAP00000014003	ENSSPAP00000021717	Mothers against decapentaplegic homolog.	Zinc and ring finger 3.	0.443
LOC103367097	LOC103367232	ENSSPAP00000028012	ENSSPAP00000005834	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.518
LOC103367097	LOC103369234	ENSSPAP00000028012	ENSSPAP00000020873	Vang-like protein.	Vang-like protein.	0.898
LOC103367097	cav1	ENSSPAP00000028012	ENSSPAP00000011525	Vang-like protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.401
LOC103367097	lrrc1	ENSSPAP00000028012	ENSSPAP00000008227	Vang-like protein.	Leucine rich repeat containing 1.	0.686
LOC103367097	scrib	ENSSPAP00000028012	ENSSPAP00000016070	Vang-like protein.	Scribble planar cell polarity protein.	0.686
LOC103367097	wnt5b	ENSSPAP00000028012	ENSSPAP00000030765	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.518
LOC103367232	LOC103367097	ENSSPAP00000005834	ENSSPAP00000028012	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Vang-like protein.	0.518
LOC103367232	LOC103369234	ENSSPAP00000005834	ENSSPAP00000020873	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Vang-like protein.	0.518
LOC103367232	wnt5b	ENSSPAP00000005834	ENSSPAP00000030765	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.899
LOC103369234	LOC103367097	ENSSPAP00000020873	ENSSPAP00000028012	Vang-like protein.	Vang-like protein.	0.898
LOC103369234	LOC103367232	ENSSPAP00000020873	ENSSPAP00000005834	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.518
LOC103369234	cav1	ENSSPAP00000020873	ENSSPAP00000011525	Vang-like protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.401
LOC103369234	lrrc1	ENSSPAP00000020873	ENSSPAP00000008227	Vang-like protein.	Leucine rich repeat containing 1.	0.686
LOC103369234	scrib	ENSSPAP00000020873	ENSSPAP00000016070	Vang-like protein.	Scribble planar cell polarity protein.	0.686
LOC103369234	wnt5b	ENSSPAP00000020873	ENSSPAP00000030765	Vang-like protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.518
cav1	LOC103367097	ENSSPAP00000011525	ENSSPAP00000028012	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Vang-like protein.	0.401
cav1	LOC103369234	ENSSPAP00000011525	ENSSPAP00000020873	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Vang-like protein.	0.401
llgl2	lrrc1	ENSSPAP00000007963	ENSSPAP00000008227	LLGL scribble cell polarity complex component 2.	Leucine rich repeat containing 1.	0.845