(34 nodes) Negative regulation of protein secretion network (Stegastes partitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	LOC103374573	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (409 aa)
	ENSSPAP00000029295	Uncharacterized protein. (102 aa)
	LOC103370062	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (356 aa)
	LOC103373401	Uncharacterized protein. (313 aa)
	LOC103366615	Motilin_assoc domain-containing protein. (106 aa)
	kcnj8	Potassium inwardly-rectifying channel, subfamily J, member 8. (419 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (310 aa)
	rhbdf1	Rhomboid 5 homolog 1a (Drosophila). (858 aa)
	ENSSPAP00000019501	FIP-RBD domain-containing protein. (81 aa)
	ENSSPAP00000012421	Nas2_N domain-containing protein. (86 aa)
	ENSSPAP00000019170	Apolipoprotein Ea. (259 aa)
	RHBDF2	Rhomboid 5 homolog 2. (836 aa)
	LOC103366446	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (409 aa)
	pim3	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (329 aa)
	LOC103367454	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family. (439 aa)
	ENSSPAP00000018954	Uncharacterized protein. (320 aa)
	drd4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa)
	LOC103373576	3-hydroxy-3-methylglutaryl coenzyme A reductase. (941 aa)
	LOC103372331	Rhomboid 5 homolog 1b (Drosophila). (807 aa)
	prkn	RBR-type E3 ubiquitin transferase. (341 aa)
	klf7	Kruppel like factor 7. (315 aa)
	LOC103371153	Midnolin. (545 aa)
	LOC103359796	Uncharacterized protein. (160 aa)
	midn	Ubiquitin-like domain-containing protein. (478 aa)
	ENSSPAP00000029281	Protein kinase domain-containing protein. (357 aa)
	ndufaf2	NADH:ubiquinone oxidoreductase complex assembly factor 2. (159 aa)
	ENSSPAP00000012016	Uncharacterized protein. (253 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (350 aa)
	kcnj11	Potassium inwardly-rectifying channel, subfamily J, member 11. (386 aa)
	CCN3	Cellular communication network factor 3. (378 aa)
	sergef	Secretion regulating guanine nucleotide exchange factor. (407 aa)
	psmd9	Proteasome 26S subunit, non-ATPase 9. (213 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000012016	LOC103366615	ENSSPAP00000012016	ENSSPAP00000001389	Uncharacterized protein.	Motilin_assoc domain-containing protein.	0.525
ENSSPAP00000012421	prkn	ENSSPAP00000012421	ENSSPAP00000007653	Nas2_N domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.890
ENSSPAP00000029281	prkn	ENSSPAP00000029281	ENSSPAP00000007653	Protein kinase domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.559
ENSSPAP00000029295	prkn	ENSSPAP00000029295	ENSSPAP00000007653	Uncharacterized protein.	RBR-type E3 ubiquitin transferase.	0.559
LOC103366446	LOC103366615	ENSSPAP00000018981	ENSSPAP00000001389	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Motilin_assoc domain-containing protein.	0.823
LOC103366446	LOC103367454	ENSSPAP00000018981	ENSSPAP00000018355	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	0.525
LOC103366446	drd3	ENSSPAP00000018981	ENSSPAP00000005227	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.747
LOC103366615	ENSSPAP00000012016	ENSSPAP00000001389	ENSSPAP00000012016	Motilin_assoc domain-containing protein.	Uncharacterized protein.	0.525
LOC103366615	LOC103366446	ENSSPAP00000001389	ENSSPAP00000018981	Motilin_assoc domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.823
LOC103366615	LOC103367454	ENSSPAP00000001389	ENSSPAP00000018355	Motilin_assoc domain-containing protein.	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	0.496
LOC103366615	LOC103374573	ENSSPAP00000001389	ENSSPAP00000005299	Motilin_assoc domain-containing protein.	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	0.823
LOC103366615	drd3	ENSSPAP00000001389	ENSSPAP00000005227	Motilin_assoc domain-containing protein.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.911
LOC103366615	drd4	ENSSPAP00000001389	ENSSPAP00000012126	Motilin_assoc domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.823
LOC103367454	LOC103366446	ENSSPAP00000018355	ENSSPAP00000018981	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.525
LOC103367454	LOC103366615	ENSSPAP00000018355	ENSSPAP00000001389	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	Motilin_assoc domain-containing protein.	0.496
LOC103367454	LOC103374573	ENSSPAP00000018355	ENSSPAP00000005299	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family.	0.525
LOC103367454	drd3	ENSSPAP00000018355	ENSSPAP00000005227	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.532
LOC103367454	drd4	ENSSPAP00000018355	ENSSPAP00000012126	Si:dkey-163m14.2; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.525
LOC103370062	il12b	ENSSPAP00000005918	ENSSPAP00000011750	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.	0.840
LOC103373576	hmgcr	ENSSPAP00000014463	ENSSPAP00000023408	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.899