(69 nodes) Negative regulation of inflammatory response network (Stegastes partitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103356527	Uncharacterized protein. (1928 aa)
	LOC103353922	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (477 aa)
	LOC103359906	Leucine rich repeat and fibronectin type III domain containing 5b. (788 aa)
	rabgef1	Uncharacterized protein. (512 aa)
	LOC103366615	Motilin_assoc domain-containing protein. (106 aa)
	LOC103358823	Cylindromatosis (turban tumor syndrome), b. (681 aa)
	LOC103360505	Phospholipase A(2). (153 aa)
	LOC103356052	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	ENSSPAP00000003583	Ig-like domain-containing protein. (129 aa)
	LOC103375162	Nuclear receptor subfamily 1, group D, member 2a. (601 aa)
	LOC103367698	Uncharacterized protein. (443 aa)
	ENSSPAP00000004244	Fibronectin type-III domain-containing protein. (217 aa)
	LOC103356322	Ash1 (absent, small, or homeotic)-like (Drosophila). (2963 aa)
	NT5E	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (549 aa)
	LOC103363855	OTU deubiquitinase with linear linkage specificity a. (750 aa)
	LOC103373247	Suppressor of cytokine signaling 3a. (205 aa)
	lpcat3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (399 aa)
	rb1	Retinoblastoma 1. (909 aa)
	LOC103363373	Si:dkey-175m17.7. (872 aa)
	ffar4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (362 aa)
	CCN3	Cellular communication network factor 3. (378 aa)
	ENSSPAP00000008436	Fibronectin type III domain containing 4a. (220 aa)
	acod1	Aconitate decarboxylase 1. (474 aa)
	LOC103364465	Zgc:194281. (213 aa)
	wfdc1	WAP four-disulfide core domain 1. (218 aa)
	LOC103369526	Granulin b. (823 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (564 aa)
	metrnl	Meteorin like, glial cell differentiation regulator a. (286 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (756 aa)
	LOC103363496	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (765 aa)
	ENSSPAP00000014968	Ig-like domain-containing protein. (258 aa)
	ENSSPAP00000014949	Uncharacterized protein. (148 aa)
	il10	Interleukin 10. (194 aa)
	mfhas1	Malignant fibrous histiocytoma amplified sequence 1. (1038 aa)
	ENSSPAP00000011040	Nuclear receptor subfamily 1, group H, member 5. (378 aa)
	LOC103371850	Prostaglandin E receptor 4 (subtype EP4) b. (477 aa)
	LOC103357298	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (773 aa)
	ENSSPAP00000011743	Uncharacterized protein. (154 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (350 aa)
	LOC103357827	RAB guanine nucleotide exchange factor (GEF) 1, like. (507 aa)
	LOC103367366	Uncharacterized protein. (298 aa)
	LOC103370704	Uncharacterized protein. (218 aa)
	LOC103360740	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	ENSSPAP00000013674	GRANULINS domain-containing protein. (146 aa)
	ENSSPAP00000013738	GRANULINS domain-containing protein. (151 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	smpdl3b	Acid sphingomyelinase-like phosphodiesterase. (457 aa)
	LOC103359160	Immunoresponsive gene 1, like. (497 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (287 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (826 aa)
	nlrx1	NLR family member X1. (965 aa)
	dusp10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	gpr17	G protein-coupled receptor 17. (336 aa)
	LOC103360973	TAFA chemokine like family member 3. (128 aa)
	ENSSPAP00000024385	Tumor necrosis factor, alpha-induced protein 6. (229 aa)
	tnfaip6	Tumor necrosis factor, alpha-induced protein 6. (167 aa)
	LOC103365293	Tumor necrosis factor receptor superfamily, member 1a. (336 aa)
	nr1d2	Nuclear receptor subfamily 1, group D, member 2b. (594 aa)
	NT5E-2	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (573 aa)
	nr1d1	Nuclear receptor subfamily 1, group d, member 1. (514 aa)
	ENSSPAP00000025275	Uncharacterized protein. (162 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (917 aa)
	LOC103376550	Leucine rich repeat and fibronectin type III domain containing 5a. (727 aa)
	ptger4	Prostaglandin E receptor 4. (477 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (473 aa)
	LOC103373233	SHANK-associated RH domain interacting protein. (323 aa)
	LOC103372658	Uncharacterized protein. (228 aa)
	LOC103362045	Nuclear receptor subfamily 1, group D, member 4a. (578 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000004244	LOC103357827	ENSSPAP00000004244	ENSSPAP00000012078	Fibronectin type-III domain-containing protein.	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.485
ENSSPAP00000004244	il10	ENSSPAP00000004244	ENSSPAP00000014937	Fibronectin type-III domain-containing protein.	Interleukin 10.	0.877
ENSSPAP00000004244	rabgef1	ENSSPAP00000004244	ENSSPAP00000001267	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.485
ENSSPAP00000011040	LOC103362045	ENSSPAP00000011040	ENSSPAP00000029729	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group D, member 4a.	0.852
ENSSPAP00000011040	LOC103375162	ENSSPAP00000011040	ENSSPAP00000003597	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group D, member 2a.	0.852
ENSSPAP00000011040	PPARA	ENSSPAP00000011040	ENSSPAP00000027380	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator-activated receptor alpha b.	0.476
ENSSPAP00000011040	PPARG	ENSSPAP00000011040	ENSSPAP00000010481	Nuclear receptor subfamily 1, group H, member 5.	Peroxisome proliferator activated receptor gamma.	0.476
ENSSPAP00000011040	nr1d1	ENSSPAP00000011040	ENSSPAP00000025193	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group d, member 1.	0.429
ENSSPAP00000011040	nr1d2	ENSSPAP00000011040	ENSSPAP00000024548	Nuclear receptor subfamily 1, group H, member 5.	Nuclear receptor subfamily 1, group D, member 2b.	0.852
ENSSPAP00000013674	LOC103365293	ENSSPAP00000013674	ENSSPAP00000024465	GRANULINS domain-containing protein.	Tumor necrosis factor receptor superfamily, member 1a.	0.415
ENSSPAP00000013738	LOC103365293	ENSSPAP00000013738	ENSSPAP00000024465	GRANULINS domain-containing protein.	Tumor necrosis factor receptor superfamily, member 1a.	0.415
ENSSPAP00000024385	il10	ENSSPAP00000024385	ENSSPAP00000014937	Tumor necrosis factor, alpha-induced protein 6.	Interleukin 10.	0.467
ENSSPAP00000024385	tnfaip6	ENSSPAP00000024385	ENSSPAP00000024442	Tumor necrosis factor, alpha-induced protein 6.	Tumor necrosis factor, alpha-induced protein 6.	0.899
LOC103353922	LOC103366615	ENSSPAP00000000444	ENSSPAP00000001389	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family.	Motilin_assoc domain-containing protein.	0.431
LOC103356052	LOC103366615	ENSSPAP00000002833	ENSSPAP00000001389	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	Motilin_assoc domain-containing protein.	0.990
LOC103356322	LOC103357827	ENSSPAP00000004428	ENSSPAP00000012078	Ash1 (absent, small, or homeotic)-like (Drosophila).	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.449
LOC103356322	il10	ENSSPAP00000004428	ENSSPAP00000014937	Ash1 (absent, small, or homeotic)-like (Drosophila).	Interleukin 10.	0.459
LOC103356322	rabgef1	ENSSPAP00000004428	ENSSPAP00000001267	Ash1 (absent, small, or homeotic)-like (Drosophila).	Uncharacterized protein.	0.449
LOC103356527	LOC103357827	ENSSPAP00000029906	ENSSPAP00000012078	Uncharacterized protein.	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.449
LOC103356527	il10	ENSSPAP00000029906	ENSSPAP00000014937	Uncharacterized protein.	Interleukin 10.	0.459