(18 nodes) Low-density lipoprotein particle receptor binding network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSPAP00000030443	Vitellogenin domain-containing protein. (2395 aa)
	ankra2	Ankyrin repeat, family A (RFXANK-like), 2. (317 aa)
	hsp90b1	Heat shock protein 90, beta (grp94), member 1. (797 aa)
	LOC103373570	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	lrpap1	Low density lipoprotein receptor-related protein associated protein 1. (347 aa)
	LOC103359525	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	dkk1	Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
	apoe	Apolipoprotein Eb. (303 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9. (669 aa)
	LOC103353121	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1684 aa)
	mesd	Mesoderm development LRP chaperone. (217 aa)
	dab2	DAB adaptor protein 2. (787 aa)
	ENSSPAP00000030517	Vitellogenin domain-containing protein. (2328 aa)
	ENSSPAP00000030537	Vitellogenin domain-containing protein. (772 aa)
	ENSSPAP00000030547	Uncharacterized protein. (414 aa)
	LOC103371606	Apolipoprotein Ba. (4357 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000030443	ENSSPAP00000030547	ENSSPAP00000030443	ENSSPAP00000030547	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.464
ENSSPAP00000030443	apoe	ENSSPAP00000030443	ENSSPAP00000017611	Vitellogenin domain-containing protein.	Apolipoprotein Eb.	0.799
ENSSPAP00000030443	dab2	ENSSPAP00000030443	ENSSPAP00000029894	Vitellogenin domain-containing protein.	DAB adaptor protein 2.	0.606
ENSSPAP00000030443	hsp90b1	ENSSPAP00000030443	ENSSPAP00000006230	Vitellogenin domain-containing protein.	Heat shock protein 90, beta (grp94), member 1.	0.601
ENSSPAP00000030443	ldlrap1	ENSSPAP00000030443	ENSSPAP00000008792	Vitellogenin domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.689
ENSSPAP00000030517	apoe	ENSSPAP00000030517	ENSSPAP00000017611	Vitellogenin domain-containing protein.	Apolipoprotein Eb.	0.799
ENSSPAP00000030517	dab2	ENSSPAP00000030517	ENSSPAP00000029894	Vitellogenin domain-containing protein.	DAB adaptor protein 2.	0.606
ENSSPAP00000030517	hsp90b1	ENSSPAP00000030517	ENSSPAP00000006230	Vitellogenin domain-containing protein.	Heat shock protein 90, beta (grp94), member 1.	0.601
ENSSPAP00000030517	ldlrap1	ENSSPAP00000030517	ENSSPAP00000008792	Vitellogenin domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.689
ENSSPAP00000030537	ENSSPAP00000030547	ENSSPAP00000030537	ENSSPAP00000030547	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.837
ENSSPAP00000030537	apoe	ENSSPAP00000030537	ENSSPAP00000017611	Vitellogenin domain-containing protein.	Apolipoprotein Eb.	0.799
ENSSPAP00000030537	dab2	ENSSPAP00000030537	ENSSPAP00000029894	Vitellogenin domain-containing protein.	DAB adaptor protein 2.	0.606
ENSSPAP00000030537	hsp90b1	ENSSPAP00000030537	ENSSPAP00000006230	Vitellogenin domain-containing protein.	Heat shock protein 90, beta (grp94), member 1.	0.601
ENSSPAP00000030537	ldlrap1	ENSSPAP00000030537	ENSSPAP00000008792	Vitellogenin domain-containing protein.	Low density lipoprotein receptor adaptor protein 1b.	0.689
ENSSPAP00000030547	ENSSPAP00000030443	ENSSPAP00000030547	ENSSPAP00000030443	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.464
ENSSPAP00000030547	ENSSPAP00000030537	ENSSPAP00000030547	ENSSPAP00000030537	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.837
ENSSPAP00000030547	apoe	ENSSPAP00000030547	ENSSPAP00000017611	Uncharacterized protein.	Apolipoprotein Eb.	0.799
ENSSPAP00000030547	dab2	ENSSPAP00000030547	ENSSPAP00000029894	Uncharacterized protein.	DAB adaptor protein 2.	0.606
ENSSPAP00000030547	hsp90b1	ENSSPAP00000030547	ENSSPAP00000006230	Uncharacterized protein.	Heat shock protein 90, beta (grp94), member 1.	0.601
ENSSPAP00000030547	ldlrap1	ENSSPAP00000030547	ENSSPAP00000008792	Uncharacterized protein.	Low density lipoprotein receptor adaptor protein 1b.	0.689