(17 nodes) Regulation of nitric-oxide synthase activity network (Stegastes partitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC103362576	Protein S100; Belongs to the S-100 family. (105 aa)
	LOC103371587	Dihydrofolate reductase. (177 aa)
	LOC103371043	Uncharacterized protein. (161 aa)
	LOC103373802	GTP cyclohydrolase 2. (226 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (473 aa)
	terf2	HTH myb-type domain-containing protein. (637 aa)
	ENSSPAP00000019170	Apolipoprotein Ea. (259 aa)
	apoe	Apolipoprotein Eb. (303 aa)
	npr3	Natriuretic peptide receptor 3. (501 aa)
	LOC103360796	GTP_cyclohydroI domain-containing protein. (246 aa)
	LOC103362339	Interleukin-1. (247 aa)
	gch1	GTP cyclohydrolase 1. (320 aa)
	ENSSPAP00000011064	S_100 domain-containing protein; Belongs to the S-100 family. (116 aa)
	LOC103368476	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (166 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (513 aa)
	dhfr	Dihydrofolate reductase. (187 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSPAP00000011064	scarb1	ENSSPAP00000011064	ENSSPAP00000003163	S_100 domain-containing protein; Belongs to the S-100 family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.443
ENSSPAP00000019170	LOC103362339	ENSSPAP00000019170	ENSSPAP00000015284	Apolipoprotein Ea.	Interleukin-1.	0.509
ENSSPAP00000019170	scarb1	ENSSPAP00000019170	ENSSPAP00000003163	Apolipoprotein Ea.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.414
LOC103360796	gch1	ENSSPAP00000016047	ENSSPAP00000012813	GTP_cyclohydroI domain-containing protein.	GTP cyclohydrolase 1.	0.868
LOC103362339	ENSSPAP00000019170	ENSSPAP00000015284	ENSSPAP00000019170	Interleukin-1.	Apolipoprotein Ea.	0.509
LOC103362339	LOC103371043	ENSSPAP00000015284	ENSSPAP00000031097	Interleukin-1.	Uncharacterized protein.	0.505
LOC103362339	apoe	ENSSPAP00000015284	ENSSPAP00000017611	Interleukin-1.	Apolipoprotein Eb.	0.409
LOC103362576	scarb1	ENSSPAP00000025942	ENSSPAP00000003163	Protein S100; Belongs to the S-100 family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.443
LOC103368476	cav3	ENSSPAP00000009514	ENSSPAP00000009502	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.931
LOC103371043	LOC103362339	ENSSPAP00000031097	ENSSPAP00000015284	Uncharacterized protein.	Interleukin-1.	0.505
LOC103373802	gch1	ENSSPAP00000024794	ENSSPAP00000012813	GTP cyclohydrolase 2.	GTP cyclohydrolase 1.	0.865
apoe	LOC103362339	ENSSPAP00000017611	ENSSPAP00000015284	Apolipoprotein Eb.	Interleukin-1.	0.409
apoe	scarb1	ENSSPAP00000017611	ENSSPAP00000003163	Apolipoprotein Eb.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.604
cav3	LOC103368476	ENSSPAP00000009502	ENSSPAP00000009514	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.931
cav3	scarb1	ENSSPAP00000009502	ENSSPAP00000003163	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.578
gch1	LOC103360796	ENSSPAP00000012813	ENSSPAP00000016047	GTP cyclohydrolase 1.	GTP_cyclohydroI domain-containing protein.	0.868
gch1	LOC103373802	ENSSPAP00000012813	ENSSPAP00000024794	GTP cyclohydrolase 1.	GTP cyclohydrolase 2.	0.865
scarb1	ENSSPAP00000011064	ENSSPAP00000003163	ENSSPAP00000011064	Scavenger receptor class B, member 1; Belongs to the CD36 family.	S_100 domain-containing protein; Belongs to the S-100 family.	0.443
scarb1	ENSSPAP00000019170	ENSSPAP00000003163	ENSSPAP00000019170	Scavenger receptor class B, member 1; Belongs to the CD36 family.	Apolipoprotein Ea.	0.414
scarb1	LOC103362576	ENSSPAP00000003163	ENSSPAP00000025942	Scavenger receptor class B, member 1; Belongs to the CD36 family.	Protein S100; Belongs to the S-100 family.	0.443