(56 nodes) Convergent extension network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	setdb2	Uncharacterized protein. (564 aa)
	invs	Inversin. (948 aa)
	adgra3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1352 aa)
	wnt5b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (758 aa)
	mcu	Mitochondrial calcium uniporter. (303 aa)
	LOC103368175	Uncharacterized protein. (184 aa)
	LOC103367097	Vang-like protein. (525 aa)
	LOC103371952	Uncharacterized protein. (341 aa)
	ENSSPAP00000026838	Protein kinase domain-containing protein. (75 aa)
	ENSSPAP00000026824	Protein kinase domain-containing protein. (77 aa)
	LOC103353777	Tyrosine-protein kinase. (538 aa)
	ENSSPAP00000026161	DUF862 domain-containing protein. (126 aa)
	ENSSPAP00000024810	Immediate early response 2b. (180 aa)
	LOC103365257	MCU domain-containing protein. (315 aa)
	amotl2	Angiomotin like 2a. (699 aa)
	LOC103374939	DUF862 domain-containing protein. (194 aa)
	LOC103373710	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (138 aa)
	LOC103369234	Vang-like protein. (526 aa)
	LOC103373678	BTB domain-containing protein. (514 aa)
	rap1a	Uncharacterized protein. (185 aa)
	tdp2	Tyrosyl-DNA phosphodiesterase 2b. (368 aa)
	LOC103376007	Protein phosphatase 1 regulatory subunit. (885 aa)
	LOC103354437	RAP1A, member of RAS oncogene family a. (231 aa)
	KLHL12	Kelch like family member 12. (598 aa)
	gdf3	Growth differentiation factor 3. (377 aa)
	scrib	Scribble planar cell polarity protein. (1689 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	bmp2	Bone morphogenetic protein 2b. (416 aa)
	YES1	Tyrosine-protein kinase. (552 aa)
	ENSSPAP00000014854	Transmembrane protein 237a. (198 aa)
	LOC103363483	Mothers against decapentaplegic homolog. (476 aa)
	LOC103358468	Mitochondrial calcium uniporter. (377 aa)
	LOC103360108	Angiomotin like 2b. (701 aa)
	ENSSPAP00000011873	Leucine rich repeat containing 6. (410 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (1081 aa)
	ofd1	OFD1 centriole and centriolar satellite protein. (1066 aa)
	def6	DEF6 guanine nucleotide exchange factor a. (619 aa)
	ENSSPAP00000009155	Mesoderm posterior ba. (132 aa)
	fibp	Fibroblast growth factor (acidic) intracellular binding protein a. (357 aa)
	LOC103360028	Transmembrane protein 237b. (408 aa)
	ENSSPAP00000008653	Dynein assembly factor 1, axonemal. (512 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa)
	lrrc1	Leucine rich repeat containing 1. (525 aa)
	ENSSPAP00000006047	SH2 domain-containing protein. (195 aa)
	LOC103367232	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	chrd	Chordin; Belongs to the chordin family. (953 aa)
	ENSSPAP00000002863	Uncharacterized protein. (149 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (333 aa)
	nphp3	Nephronophthisis 3. (1306 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
	LOC103368849	T-box transcription factor Ta. (398 aa)
	LOC103361570	Tyrosine-protein kinase. (547 aa)
	ENSSPAP00000000647	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	LOC103355473	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (918 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC103355473	ENSSPAP00000001222	ENSSPAP00000000369	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.899
CDH2	ctnnb1	ENSSPAP00000001222	ENSSPAP00000015579	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Catenin (cadherin-associated protein), beta 1.	0.884
ENSSPAP00000000647	PTK7	ENSSPAP00000000647	ENSSPAP00000008528	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.425
ENSSPAP00000002863	ENSSPAP00000014854	ENSSPAP00000002863	ENSSPAP00000014854	Uncharacterized protein.	Transmembrane protein 237a.	0.419
ENSSPAP00000002863	LOC103360028	ENSSPAP00000002863	ENSSPAP00000008662	Uncharacterized protein.	Transmembrane protein 237b.	0.419
ENSSPAP00000002863	nphp3	ENSSPAP00000002863	ENSSPAP00000001894	Uncharacterized protein.	Nephronophthisis 3.	0.534
ENSSPAP00000002863	ofd1	ENSSPAP00000002863	ENSSPAP00000010303	Uncharacterized protein.	OFD1 centriole and centriolar satellite protein.	0.524
ENSSPAP00000006047	ENSSPAP00000026838	ENSSPAP00000006047	ENSSPAP00000026838	SH2 domain-containing protein.	Protein kinase domain-containing protein.	0.421
ENSSPAP00000006047	LOC103354437	ENSSPAP00000006047	ENSSPAP00000019043	SH2 domain-containing protein.	RAP1A, member of RAS oncogene family a.	0.626
ENSSPAP00000006047	LOC103361570	ENSSPAP00000006047	ENSSPAP00000000757	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.900
ENSSPAP00000006047	LOC103363483	ENSSPAP00000006047	ENSSPAP00000014003	SH2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.430
ENSSPAP00000006047	LOC103368175	ENSSPAP00000006047	ENSSPAP00000028612	SH2 domain-containing protein.	Uncharacterized protein.	0.626
ENSSPAP00000006047	PTK7	ENSSPAP00000006047	ENSSPAP00000008528	SH2 domain-containing protein.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.616
ENSSPAP00000006047	YES1	ENSSPAP00000006047	ENSSPAP00000015137	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.900
ENSSPAP00000006047	bmp2	ENSSPAP00000006047	ENSSPAP00000015145	SH2 domain-containing protein.	Bone morphogenetic protein 2b.	0.424
ENSSPAP00000006047	ctnnb1	ENSSPAP00000006047	ENSSPAP00000015579	SH2 domain-containing protein.	Catenin (cadherin-associated protein), beta 1.	0.894
ENSSPAP00000006047	gdf3	ENSSPAP00000006047	ENSSPAP00000016590	SH2 domain-containing protein.	Growth differentiation factor 3.	0.424
ENSSPAP00000006047	rap1a	ENSSPAP00000006047	ENSSPAP00000019988	SH2 domain-containing protein.	Uncharacterized protein.	0.626
ENSSPAP00000006047	tab2	ENSSPAP00000006047	ENSSPAP00000029955	SH2 domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.515
ENSSPAP00000008653	ENSSPAP00000011873	ENSSPAP00000008653	ENSSPAP00000011873	Dynein assembly factor 1, axonemal.	Leucine rich repeat containing 6.	0.511