(14 nodes) Embryonic retina morphogenesis in camera-type eye network (Stegastes partitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
	LOC103355473	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (918 aa)
	ENSSPAP00000009545	LIM zinc-binding domain-containing protein. (68 aa)
	lhx1	LIM homeobox 1a. (316 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
	LOC103354198	Forkhead box Q2. (221 aa)
	mpp5	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (650 aa)
	MPP5	Membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (629 aa)
	FOXC1	Forkhead box C1. (468 aa)
	gdf5	Growth differentiation factor 5. (462 aa)
	ENSSPAP00000024484	Forkhead box C1. (204 aa)
	gdf6	Growth differentiation factor 6a. (444 aa)

Your Current Organism:

Stegastes partitus

NCBI taxonomy Id: 144197
Other names: S. partitus, bicolor damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC103355473	ENSSPAP00000001222	ENSSPAP00000000369	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.899
LOC103355473	CDH2	ENSSPAP00000000369	ENSSPAP00000001222	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.899
MPP5	mpp5	ENSSPAP00000021854	ENSSPAP00000021298	Membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	0.900
fgf3	fgf8	ENSSPAP00000029108	ENSSPAP00000018468	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.818
fgf8	fgf3	ENSSPAP00000018468	ENSSPAP00000029108	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.818
mpp5	MPP5	ENSSPAP00000021298	ENSSPAP00000021854	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	Membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	0.900